Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

New PET radiotracer effectively detects early and advanced stages of prostate cancer

In the featured article from the February 2017 issue of the Journal of Nuclear Medicine, researchers document the first-in-human application of a new imaging agent to help find prostate cancer in both early and advanced stages and plan treatment.

1 Feb 2017

Research provides insight into how melanoma and other cancers spread from solid tumors

In a second human case, a Yale-led research team has found that a melanoma cell and a white blood cell can fuse to form a hybrid with the ability to metastasize. The finding provides further insight into how melanoma and other cancers spread from solid tumors with implications for future treatment.

30 Jan 2017

Breast conserving therapy better than mastectomy in early-stage breast cancer patients

Breast conserving therapy (BCT, breast conserving surgery combined with radiation therapy) is superior to mastectomy in certain types of breast cancer patients, according to results from the largest study to date, to be presented to the European Cancer Congress 2017 today.

30 Jan 2017

Hypoxia in primary tumors influences dormant DTCs that evade cancer therapy, study shows

In a first of its kind study, Mount Sinai researchers have discovered the conditions by which specific signals in primary tumors of head and neck and breast cancers, pre-program cancer cells to become dormant and evade chemotherapy after spreading.

28 Jan 2017

Study shows how microRNA molecule promotes prostate cancer metastasis

RAISED levels of a tiny molecule in the bloodstream have been linked with prostate cancer metastasis, potentially helping researchers detect the spread of the disease sooner.

27 Jan 2017

Adelaide researchers uncover new pathway that regulates spread of prostate cancer

University of Adelaide researchers have uncovered a new pathway which regulates the spread of prostate cancer around the body.

26 Jan 2017

Natural compound could reduce risk of developing triple-negative breast cancer metastasis

More than 100 women die from breast cancer every day in the United States. Triple-negative breast cancers, which comprise 15 to 20 percent of all breast tumors, are a particularly deadly type of breast disease that often metastasize to distant sites.

24 Jan 2017

Researchers investigate influence of surrounding tissue on formation and growth of tumor cells

Malignant melanoma is the fastest-growing type of cancer and the most fatal skin disease.

23 Jan 2017

RIT research explores impact of shear stress on cells moving through blood vessels

How do cells and protein molecules respond to stress as they travel through blood vessels? Could resulting changes to these biological components impact how diseases are spread?

19 Jan 2017

Researchers uncover structure of cancer cell receptor protein that paves way for drug development

A team of researchers from Case Western Reserve University School of Medicine has helped uncover the elusive structure of a cancer cell receptor protein that can be leveraged to fight disease progression.

19 Jan 2017

Stem cell research offers alternative view of cancer metastasis

Stem cells are among the most energetically activated, migratory and proliferative sub-populations of tumour cells, according to observations by scholars at the Biomedical Research Centre at the University of Salford.

18 Jan 2017

Protein involved in pancreatic cancer development plays more complicated role, study finds

A protein thought to fuel pancreatic cancer development plays a much more complicated role, a new study finds.

18 Jan 2017

Chemotherapy-induced senescent cells promote side effects and cancer relapse

Standard chemotherapy is a blunt force instrument against cancer - and it's a rare cancer patient who escapes debilitating side effects from systemic treatments that mostly affect dividing cells, both malignant and healthy, throughout the body.

17 Jan 2017

Epigenetic changes drive successful metastases of pancreatic cancer cells

A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells.

17 Jan 2017

Ludwig study uncovers ancient cellular response that underlies spread of aggressive skin cancer

Each day, more than 1,600 people die from cancer in the US, and 450 in the UK, mostly because the disease has spread beyond a stage when surgery is an effective cure and has become resistant to therapy. Despite decades of research, understanding why cancer cells become invasive has remained shrouded in mystery.

17 Jan 2017

MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

Massachusetts General Hospital investigators have identified a protein that may play an essential role in maintaining a population of tumor-initiating cells (TICs) -- treatment-resistant cells responsible for cancer recurrence and metastasis -- in breast cancer, as well as a compound that appears to reduce the molecule's ability to protect TICs from the effects of chemotherapy.

17 Jan 2017

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Metastatic pancreatic cancer -- cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths -- changes its metabolism and is "reprogrammed" for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics.

16 Jan 2017

Metastasis News and Research

Further Reading

New PET radiotracer effectively detects early and advanced stages of prostate cancer

Research provides insight into how melanoma and other cancers spread from solid tumors

Breast conserving therapy better than mastectomy in early-stage breast cancer patients

Hypoxia in primary tumors influences dormant DTCs that evade cancer therapy, study shows

Study shows how microRNA molecule promotes prostate cancer metastasis

Adelaide researchers uncover new pathway that regulates spread of prostate cancer

Natural compound could reduce risk of developing triple-negative breast cancer metastasis

Researchers investigate influence of surrounding tissue on formation and growth of tumor cells

RIT research explores impact of shear stress on cells moving through blood vessels

Researchers uncover structure of cancer cell receptor protein that paves way for drug development

Stem cell research offers alternative view of cancer metastasis

Protein involved in pancreatic cancer development plays more complicated role, study finds

Chemotherapy-induced senescent cells promote side effects and cancer relapse

Epigenetic changes drive successful metastases of pancreatic cancer cells

Ludwig study uncovers ancient cellular response that underlies spread of aggressive skin cancer

MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

MUSC scientists design novel antibody-based therapy to fight against cancer

Roswell Park researchers identify gene signatures that may help predict fatal prostate cancers

Research findings may provide new treatment for prevention of cancer metastasis

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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