Microscopy News and Research

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Breakthrough discovery could pave the way for new non-opioid painkillers to treat neuropathic pain

Monash University researchers have made a breakthrough discovery that could pave the way for the development of novel non-opioid painkillers to safely and effectively treat neuropathic pain.

8 Sep 2021

Scientists model the process of capsid disassembly in hepatitis B virus at atomic level

With up to 2.4 million U.S. cases and over 250 million chronic cases globally, hepatitis B infection persists despite the availability of a vaccine.

8 Sep 2021

New imaging technique uses photonics for early diagnosis of bowel cancer

Early intervention could prevent many of the 160,000 deaths from colon cancer in Europe each year. Colonoscopies, the gold standard for spotting bowel cancer early, can still miss up to 20% of precancerous cells.

7 Sep 2021

Neuroscientists visualize ultrastructural changes to dendritic spines during structural plasticity

Researchers at the Max Planck Florida Institute for Neuroscience have developed a new imaging technique capable of visualizing the dynamically changing structure of dendritic spines with unprecedented resolution.

6 Sep 2021

Study identifies how immune sensors launch a multi-faceted innate immune response to infections

St. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and launch a multi-faceted innate immune response to infections with live viruses and bacteria. The discovery appears today in Nature.

2 Sep 2021

Uppsala researchers find solution to long-standing biological search enigma

How the cell can mend broken DNA using another DNA copy as template has puzzled researchers for years. How is it possible to find the correct sequences in the busy interior of the cell? Researchers from Uppsala university have now discovered the solution; it is easier to find a rope than a ball if you are blindfolded.

1 Sep 2021

Research offers insights to restore blood vessel integrity during sepsis, other conditions

Sepsis occurs when the body works so hard to fight an infection that the over-activated immune system harms a patient's own tissues as collateral damage.

31 Aug 2021

Development of extra protective broad-spectrum antimicrobial face shield

In a new study available on the preprint server Preprints*, researchers have innovated a transparent face shield with intrinsic antimicrobial activity.

30 Aug 2021

Study reveals how SARS-CoV-2 variants of concern modulate receptor and antibody binding

In a trailblazing engineering effort, Canadian and US researchers indicate that the emergence of novel variants of SARS-CoV-2 stems from the mutations of spike glycoprotein that confer either increased affinity for the host cell receptor or increased antibody evasion.

30 Aug 2021

New study maps the evolution of the SARS-CoV-2 delta and delta plus variants

The SARS-CoV-2 delta variant bears the D164G mutation, which is known to enhance viral fitness. However, a number of additional mutations are known to be common to the delta and delta plus lineages, at least 25 as identified in a study recently published in the Journal of Autoimmunity, mainly located on the spike protein of the virus.

30 Aug 2021

Olympus Announces First Organoid Conference to Support Stem Cell Research

Olympus is proud to announce its first Olympus Organoid Conference—Think Deep, See Deeper, which will be held virtually on Sept. 7–9, 2021.

From Evident Corporation - Life Sciences 27 Aug 2021

Brain refreshing takes place during the dream-active phase of sleep

Scientists have long wondered why almost all animals sleep, despite the disadvantages to survival of being unconscious.

25 Aug 2021

Study finds a new line of drugs to stimulate myelin repair in multiple sclerosis

In the nearly 1 million Americans living with multiple sclerosis, the fatty substance that insulates the nerves of the central nervous system—called myelin—is damaged.

24 Aug 2021

Atomic-level imaging of infectious prions reveals new therapeutic targets for untreatable diseases

The highest-ever resolution imaging of an infectious prion provides the first atomic-level data of how these abnormal proteins are assembled to cause fatal neurodegenerative diseases in people and animals - and how they can be potentially targeted by new therapies.

24 Aug 2021

Study suggests algorithm may help optimize future COVID-19 vaccine design

Scientists predict the COVID-19 pandemic is on its way to becoming endemic. The rising spread of COVID-19 variants such as Delta has helped infect unvaccinated and some vaccinated individuals. COVID-19 vaccines continue to be the best way to protect against severe illness and death, but there may be a need for vaccines to protect against a specific variant.

23 Aug 2021

New mathematical model can predict the optimum exercise regime for building muscle

Researchers have developed a mathematical model that can predict the optimum exercise regime for building muscle.

23 Aug 2021

New analytical method visualizes cell functions in vasculature-on-a-chip

A microphysiological system (MPS), also known as an organ-on-a-chip, is a 3D organ construct using human cells that help reveal how organs respond to drugs and environmental stimuli.

20 Aug 2021

Scientists identify the main components driving amyloid beta-associated synapse degeneration

Healthy adult brains are endowed with a vast number of synapses, structures that relay signals across nerve cells to enable communications, information processing and storage throughout the nervous system.

18 Aug 2021

Videos capture the inexorable spread of SARS-CoV-2 in live animals

Video images capture for the first time in live animals the inexorable spread of the COVID-19 virus, tracking the infection as it moved from the noses of mice to the lungs and other organs over the course of six days, in a new study led by researchers at Yale and Université de Montréal.

18 Aug 2021

How do glycans affect SARS-CoV-2 spike protein openings?

In a paper recently uploaded to the bioRxiv* preprint server, the role of glycan coating on the SARS-CoV-2 spike protein is further investigated by molecular dynamics simulations of the glycosylated and non-glycosylated protein, identifying several key glycans that play a role in stabilizing and protecting the RBD, and also encourage bonding with the ACE2 receptor.

18 Aug 2021

Microscopy News and Research

Breakthrough discovery could pave the way for new non-opioid painkillers to treat neuropathic pain

Scientists model the process of capsid disassembly in hepatitis B virus at atomic level

New imaging technique uses photonics for early diagnosis of bowel cancer

Neuroscientists visualize ultrastructural changes to dendritic spines during structural plasticity

Study identifies how immune sensors launch a multi-faceted innate immune response to infections

Uppsala researchers find solution to long-standing biological search enigma

Research offers insights to restore blood vessel integrity during sepsis, other conditions

Development of extra protective broad-spectrum antimicrobial face shield

Study reveals how SARS-CoV-2 variants of concern modulate receptor and antibody binding

New study maps the evolution of the SARS-CoV-2 delta and delta plus variants

Olympus Announces First Organoid Conference to Support Stem Cell Research

Brain refreshing takes place during the dream-active phase of sleep

Study finds a new line of drugs to stimulate myelin repair in multiple sclerosis

Atomic-level imaging of infectious prions reveals new therapeutic targets for untreatable diseases

Study suggests algorithm may help optimize future COVID-19 vaccine design

New mathematical model can predict the optimum exercise regime for building muscle

New analytical method visualizes cell functions in vasculature-on-a-chip

Scientists identify the main components driving amyloid beta-associated synapse degeneration

Videos capture the inexorable spread of SARS-CoV-2 in live animals

How do glycans affect SARS-CoV-2 spike protein openings?

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