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Pfizer starts Phase 1/2 study of RSV vaccine candidate in healthy adult volunteers

Pfizer Inc. today announced that it has started a Phase 1/2 trial of its respiratory syncytial virus (RSV) vaccine candidate in healthy adult volunteers. RSV is a common respiratory virus that affects the lungs and airways, with significant impact on young children and older adults.

22 May 2018

Researchers shed light on how androgen deprivation therapy increases risk for cardiovascular mortality

Prostate cancer is the most common cancer in men in the US. As the prostate is a testosterone-responsive gland, androgen deprivation therapy is the cornerstone of treatment in these men, with approximately 50 percent of prostate cancer patients starting ADT within a year of diagnosis.

22 May 2018

PCI along with prescribed drugs better than medication alone for treating for people with heart disease

A non-surgical procedure, called percutaneous coronary intervention, along with prescribed medication, is better than medication alone as initial treatment for people who have the most common form of heart disease, suggests an analysis of an international clinical trial co-led by St. Michael's Hospital.

22 May 2018

Scientists decipher workings of little-understood bacterial riboswitch

In a discovery that points to potential new antibiotic medicines, scientists from Rice University and the University of Michigan have deciphered the workings of a common but little-understood bacterial switch that cuts off protein production before it begins.

22 May 2018

Are you and your primary care doc ready to talk about your DNA?

If you have a genetic mutation that increases your risk for a treatable medical condition, would you want to know? For many people the answer is yes. But such information is not commonly part of routine primary care.

22 May 2018

Scientists reveal mechanisms that may help preterm infants extend nephron development window

Nephrons are the microscopic blood-filtering units inside our kidneys that convert waste products into urine, regulate our electrolyte levels and our blood pressure.

22 May 2018

Proteins moderating nicotine dependence may help fat cells burn energy

The same proteins that moderate nicotine dependence in the brain may be involved in regulating metabolism by acting directly on certain types of fat cells, new research from the University of Michigan Life Sciences Institute shows.

22 May 2018

PSCK9 inhibitors may provide benefit to atherosclerosis patients with high lipoprotein(a) levels

Lipoprotein(a) is a variant of LDL (low-density lipoprotein) cholesterol, and large amounts of data have shown that higher lipoprotein(a) levels are associated with an increased risk of cardiovascular events.

22 May 2018

Researchers uncover clues to early lung transplant failure

Among organ transplant patients, those receiving new lungs face a higher rate of organ failure and death compared with people undergoing heart, kidney and liver transplants. One of the culprits is inflammation that damages the newly transplanted lung.

22 May 2018

Combination of vascular risk and brain amyloid levels may accelerate age-related cognitive decline

Risk factors for heart disease and stroke appear to hasten the risk of cognitive decline in normal older individuals with evidence of very early Alzheimer's-disease-associated changes in the brain.

22 May 2018

Mediterranean diet may protect people from negative effects of air pollution

Eating a Mediterranean diet may protect people from some of the harm of long-term exposure to air pollution, and reduce their risk of dying from heart attacks, stroke and other causes of death, according to new research presented at the ATS 2018 International Conference.

21 May 2018

Flavonoid intake may reduce lung function decline that occurs with aging

A type of flavonoid found in dark-pigmented fruits like red grapes and blueberries may slow the lung function decline that occurs with aging, according to new research presented at the ATS 2018 International Conference.

21 May 2018

Study finds increase in number of calls to US Poison Control Centers about ADHD medication exposures

A new study conducted by the Center for Injury Research and Policy and the Central Ohio Poison Center at Nationwide Children's Hospital found that there were more than 156,000 calls to US Poison Control Centers regarding exposures to attention-deficit hyperactivity disorder medications among children and adolescents 19 years of age and younger from January 2000 through December 2014, averaging 200 calls each week or 29 calls per day.

21 May 2018

Study: Exercising for 4-5 days per week is needed to keep the heart young

Participating in exercise 4-5 days per week is necessary to keep your heart young, according to new research published in The Journal of Physiology.

21 May 2018

Researchers discover new disease mechanism in chronic tobacco smokers

Research published in the journal Clinical Science suggests that an immune signaling protein called interleukin-26 is increased among chronic smokers with lung disease and this involvement reveals disease mechanisms of interest for developing more effective therapy for these hard-to-treat patients.

21 May 2018

Study: Prediabetic patients with OSA could lower their resting heart rates by using CPAP

Patients with prediabetes who also have obstructive sleep apnea may improve their resting heart rate, an important measure of cardiovascular health, by using continuous positive airway pressure to treat their OSA, according to a randomized, controlled trial presented at the ATS 2018 International Conference.

21 May 2018

Intermittent fasting may increase diabetes risk, shows study

Fasting every other day to lose weight impairs the action of sugar-regulating hormone, insulin, which may increase diabetes risk, according to data presented in Barcelona at the European Society of Endocrinology annual meeting, ECE 2018.

21 May 2018

Reduction in heart disease risk factors could help prevent frailty among older adults

New research has shown that older people with very low heart disease risks also have very little frailty, raising the possibility that frailty could be prevented.

21 May 2018

New technique allows researchers to control heart cells growing in a dish

Researchers at University of California San Diego School of Medicine and their collaborators have developed a technique that allows them to speed up or slow down human heart cells growing in a dish on command - simply by shining a light on them and varying its intensity.

21 May 2018

Incorporation of AI could transform cancer diagnosis in UK - PM May

According to Prime Minister Theresa May, Artificial Intelligence (AI) is soon to change the scene in cancer and other disease diagnosis. She is to speak today in Macclesfield where she would acknowledge AI as a “new weapon” that is being used by the NHS and technology companies in research.

21 May 2018

Heart News and Research

Pfizer starts Phase 1/2 study of RSV vaccine candidate in healthy adult volunteers

Researchers shed light on how androgen deprivation therapy increases risk for cardiovascular mortality

PCI along with prescribed drugs better than medication alone for treating for people with heart disease

Scientists decipher workings of little-understood bacterial riboswitch

Are you and your primary care doc ready to talk about your DNA?

Scientists reveal mechanisms that may help preterm infants extend nephron development window

Proteins moderating nicotine dependence may help fat cells burn energy

PSCK9 inhibitors may provide benefit to atherosclerosis patients with high lipoprotein(a) levels

Researchers uncover clues to early lung transplant failure

Combination of vascular risk and brain amyloid levels may accelerate age-related cognitive decline

Mediterranean diet may protect people from negative effects of air pollution

Flavonoid intake may reduce lung function decline that occurs with aging

Study finds increase in number of calls to US Poison Control Centers about ADHD medication exposures

Study: Exercising for 4-5 days per week is needed to keep the heart young

Researchers discover new disease mechanism in chronic tobacco smokers

Study: Prediabetic patients with OSA could lower their resting heart rates by using CPAP

Intermittent fasting may increase diabetes risk, shows study

Reduction in heart disease risk factors could help prevent frailty among older adults

New technique allows researchers to control heart cells growing in a dish

Incorporation of AI could transform cancer diagnosis in UK - PM May

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