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CHOP researchers use machine-learning models for early detection of sepsis in NICU infants

Automated programs can identify which sick infants in a neonatal intensive care unit (NICU) have sepsis hours before clinicians recognize the life-threatening condition.

1 Mar 2019

U.S.-funded initiative associated with reductions in maternal and newborn mortality in Indonesia

A U.S.-funded initiative to improve quality of care and referrals during pregnancy and childbirth in Indonesia resulted in significant reductions in maternal and newborn mortality at participating hospitals, according to a new study led by scientists at the Johns Hopkins Bloomberg School of Public Health.

28 Feb 2019

Prenatal vitamins may reduce the risk of autism in high-risk families

Researchers have found that mothers of children with autism may be able to reduce the risk of autism in further offspring by taking prenatal vitamins.

28 Feb 2019

Lactose-free, reduced-carbohydrate milk does not improve outcomes in severely malnourished children

Treating hospitalized, severely malnourished children with a lactose-free, reduced-carbohydrate milk formula does not improve clinical outcomes, according to a study published February 26 in the open-access journal PLOS Medicine by Robert Bandsma of the Hospital for Sick Children in Toronto, Canada, James Berkley of the KEMRI/Wellcome Trust Research Programme in Kilifi, Kenya, and colleagues.

28 Feb 2019

Infants born with heart defects more likely to develop heart problems later in life

An infant born with a relatively simple heart defect is far more likely to develop heart problems as an adult, researchers at the Stanford University School of Medicine have discovered.

28 Feb 2019

Researchers are developing and testing novel gene therapy to cure Crigler-Najjar syndrome

Crigler-Najjar syndrome affects about one in a million people at birth. Because of a defective gene, these individuals lack an essential enzyme in their liver to eliminate bilirubin, a toxic bile pigment that accumulates in all body tissues causing jaundice and potentially leading to irreversible and lethal neurological damage.

28 Feb 2019

Persistant opioid use in the family may be risk factor for young adults after surgery

Having a family member with persistent opioid use may be a risk factor for young adults continuing prescriptions long after their own surgeries, a new Michigan Medicine study suggests.

28 Feb 2019

Study finds link between infant sleep duration and mother's level of education, prenatal depression

A new study analyzing data from Canadian parents has found that babies sleep less at three months of age if their mothers do not have a university degree, experienced depression during pregnancy or had an emergency cesarean-section delivery.

28 Feb 2019

Study examines if maternal prenatal vitamin use is linked to autism recurrence

This study examined whether prenatal vitamin use by mothers was associated with autism spectrum disorder recurrence in high-risk families.

28 Feb 2019

Detention centers in California lack oversight and proper care, reports find

Staff members at immigration detention centers in California delayed medical appointments for patients complaining of shortness of breath. They inadequately supervised suicidal youths. And in one case, they failed to refer a patient with dangerously low blood pressure to a physician.

28 Feb 2019

New model could help predict risk of suicidal behavior in at-risk young adults

Suicide is the second leading cause of death in the U.S. among those aged 15 to 34 years and yet, despite years of mental health research, our ability to predict suicidal behavior is only slightly better than chance.

27 Feb 2019

Researchers discover new mechanism of bone growth

In a paper published in the journal Nature, an international research team led by researchers at Karolinska Institutet in Sweden report that bone growth in mice takes place in accordance with the same principles as when new cells are constantly produced in blood, skin and other tissue.

27 Feb 2019

Study tracks drinking habits of new parents

Most women dramatically reduce their alcohol intake on learning they are pregnant, but by the time their child is five they are back to their pre-pregnancy drinking levels, a new international study has found.

27 Feb 2019

Study makes breakthrough in identifying cause of severe child speech impediment

An international study led by the Murdoch Children's Research Institute has made a breakthrough in identifying a potential cause of the most severe child speech impediment - apraxia.

27 Feb 2019

Almost half of all childhood cancer cases go undiagnosed

A new study estimates that almost half of all children in the world who have cancer are not diagnosed or treated, leaving them to “die at home.”

27 Feb 2019

Scientists develop tool to screen children for fetal alcohol spectrum disorder

Scientists at the University of Southern California, Queen's University and Duke University have developed a new tool that can screen children for fetal alcohol spectrum disorder quickly and affordably, making it accessible to more children in remote locations worldwide.

27 Feb 2019

Machine learning tool could prevent unnecessary treatments for kids with arthritis

Arthritis is not just an ailment of old age--it can affect children too, causing lifelong pain and disability in its most severe forms. Fortunately, some kids grow out of it. Knowing which patients will develop milder forms of disease could spare them unnecessary treatment and potential medication side effects but currently doctors have no way of predicting disease course or severity.

27 Feb 2019

Existing drug for rare kidney disease could benefit patients with mitochondrial disorders

New preclinical findings from extensive cell and animal studies suggest that a drug already used for a rare kidney disease could benefit patients with some mitochondrial disorders--complex conditions with severe energy deficiency for which no proven effective treatments exist.

27 Feb 2019

New study shows that people with dyslexia have structural dysfunction in subcortical region

Developmental dyslexia is one of the most widespread learning disabilities. Different therapeutic approaches and learning strategies are used to tackle the reading and writing difficulties associated with dyslexia, but to-date it is impossible to cure dyslexia.

27 Feb 2019

Brain response to mom's voice found to be greatly diminished in children with autism

For most children, the sound of their mother's voice triggers brain activity patterns distinct from those triggered by an unfamiliar voice. But the unique brain response to mom's voice is greatly diminished in children with autism, according to a new study from the Stanford University School of Medicine.

26 Feb 2019

Children News and Research

CHOP researchers use machine-learning models for early detection of sepsis in NICU infants

U.S.-funded initiative associated with reductions in maternal and newborn mortality in Indonesia

Prenatal vitamins may reduce the risk of autism in high-risk families

Lactose-free, reduced-carbohydrate milk does not improve outcomes in severely malnourished children

Infants born with heart defects more likely to develop heart problems later in life

Researchers are developing and testing novel gene therapy to cure Crigler-Najjar syndrome

Persistant opioid use in the family may be risk factor for young adults after surgery

Study finds link between infant sleep duration and mother's level of education, prenatal depression

Study examines if maternal prenatal vitamin use is linked to autism recurrence

Detention centers in California lack oversight and proper care, reports find

New model could help predict risk of suicidal behavior in at-risk young adults

Researchers discover new mechanism of bone growth

Study tracks drinking habits of new parents

Study makes breakthrough in identifying cause of severe child speech impediment

Almost half of all childhood cancer cases go undiagnosed

Scientists develop tool to screen children for fetal alcohol spectrum disorder

Machine learning tool could prevent unnecessary treatments for kids with arthritis

Existing drug for rare kidney disease could benefit patients with mitochondrial disorders

New study shows that people with dyslexia have structural dysfunction in subcortical region

Brain response to mom's voice found to be greatly diminished in children with autism

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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