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Scientists discover promising new target to fight a class of viruses

Scientists at the Morgridge Institute for Research have discovered a promising new target to fight a class of viruses responsible for health threats such as Zika, polio, dengue, SARS and hepatitis C.

25 Jan 2018

Researchers identify promising new drug target for Ewing sarcoma

Screening a class of recently-developed drug compounds -- so-called "CDK inhibitors" capable of blocking CDK7/12/13 proteins -- against hundreds of different human cancer cell lines, researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center have found that CDK12 inhibitors pack a particularly lethal punch to Ewing sarcoma, a rare cancer typically affecting children and young adults.

25 Jan 2018

Biologists discover new genetic pathway for injured nerve regeneration

On the hunt for genes involved in regenerating critical nerve fibers called axons, biologists at the University of California San Diego came away with a surprise: The discovery of a new genetic pathway that carries hope for victims of traumatic injuries - from stroke to spinal cord damage.

25 Jan 2018

American Pain Society's 2018 conference aims to deepen understanding of pain mechanisms

The American Pain Society, www.americanpainsociety.org, has changed the format for its 2018 conference to a Scientific Summit titled "Understanding Pain Mechanisms." The event is March 4-6 at the Disneyland Hotel in Anaheim.

25 Jan 2018

New test predicts which BRCA2 gene mutations lead to breast, ovarian cancers

A new test developed by researchers at Mayo Clinic shows which mutations in the BRCA2 gene make women susceptible to developing breast or ovarian cancers. The research behind the test was published today in the American Journal of Human Genetics.

25 Jan 2018

Researchers find new method to overcome major challenge of stem cell therapy

Researchers have discovered a new technique that overcomes one of the major challenges of stem cell therapy.

25 Jan 2018

Repurposed drug effectively protects against Zika virus in mouse models

In both cell cultures and mouse models, a drug used to treat Hepatitis C effectively protected and rescued neural cells infected by the Zika virus -- and blocked transmission of the virus to mouse fetuses.

25 Jan 2018

UTokyo enters into agreement for developing personalized cancer vaccine

The University of Tokyo entered an agreement for developing a personalized cancer vaccine using a novel method involving the body's immune response.

25 Jan 2018

Enhanced lifestyle counseling prevents cognitive decline even in genetically susceptible people

Enhanced lifestyle counseling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer's disease, according to a new study published in JAMA Neurology.

25 Jan 2018

Researchers find link between genetic molecules in mosquitos and dengue fever

Researchers at the University of Missouri have found a link between genetic molecules in mosquitos and dengue fever.

25 Jan 2018

Researchers uncover molecular roots of genetic lung disease

Respiratory infections peak during the winter months, and most people recover within a few weeks. But for those with a rare genetic lung disease, the sniffling, coughing and congestion never end.

24 Jan 2018

Valproic acid exposure results in characteristics linked to autism, zebrafish study shows

Exposure to a compound used to treat migraines and seizures causes characteristics associated with autism, groundbreaking research with zebrafish has demonstrated.

24 Jan 2018

Peripheral nerve cells play key role in wound healing process, research shows

Nerve cells in the skin help wounds to heal. When an injury occurs, cells known as glial cells change into repair cells and disseminate into the wound, where they help the skin to regenerate, researchers from the University of Zurich have shown.

24 Jan 2018

Researchers grow human trophoblast stem cells for the first time

In a milestone achievement for better understanding the development and function of the human placenta, scientists have derived and grown trophoblast stem cells for the first time.

24 Jan 2018

UCSF researchers find new way to attack common drivers of 'undruggable' cancers

Cancer researchers have made great strides in developing targeted therapies that treat the specific genetic mutations underlying a patient's cancer.

24 Jan 2018

Leading medical societies update molecular testing guideline for lung cancer

Rapid advancements in the molecular diagnostic testing of lung cancer have led to new treatments and greater hope for patients battling lung cancer, the most common cause of cancer death worldwide.

24 Jan 2018

Scientists aim to decipher language of DNA

Yes, DNA has its own language and scientists want to understand it to apply personalized therapeutic solutions based on the analysis of the individual's genomic biomarkers and their regulation.

24 Jan 2018

Scientists elucidate surprising dual function of ceramide synthase

Scientists at the University of Bonn have clarified a surprising dual function of ceramide synthase. The enzyme not only catalyzes a central step of the production of vital lipids. It also has the ability to turn genes involved in lipid metabolism on or off. The study is being published in the renowned journal Cell Reports.

24 Jan 2018

Genome analysis reveals leprosy's origin and drug resistance

Leprosy is an infectious disease with gruesome symptoms. It damages the skin, peripheral nerves, the upper respiratory tract, and the eyes.

24 Jan 2018

Study shows link between epilepsy and structural differences in grey matter

Research carried out by researchers at RCSI in partnership with UCL and the Keck School of Medicine of USC has revealed an association between epilepsy and the thickness and volume differences in the grey matter of several brain regions. The research is published today in Brain.

24 Jan 2018