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Women who experience acute aortic dissection are more likely to die than men, shows study

Women who experience acute aortic dissection - a spontaneous and catastrophic tear in one of the body's main arteries - not only are older and have more advanced disease than men when they seek medical care, but they also are more likely to die, according to research published online today in The Annals of Thoracic Surgery.

2 Jun 2021

Researchers identify new approach to clear toxic Huntingtin protein

Researchers world-wide are focused on clearing the toxic mutant Huntingtin protein that leads to neuronal cell death and systemic dysfunction in Huntington's disease (HD), a devastating, incurable, progressive neurodegenerative genetic disorder.

2 Jun 2021

Natural Killer cells acts as a potential target of immunotherapy, shows study

Despite a name straight from a Tarantino movie, natural killer (NK) cells are your allies when it comes to fighting infections and cancer.

2 Jun 2021

Positive COVID-19 screening test helps monitor respiration rate, blood-oxygen saturation at home

Two easily measurable signs of health - respiration rate and blood-oxygen saturation - are distinctly predictive of higher mortality among patients hospitalized with COVID-19, according to a study examining the cases of inpatients with COVID-19 at Rush University Medical Center and University of Washington Medicine hospitals.

2 Jun 2021

Revolutionary material senses and powers itself, may lead to new generation of living structures

From the biggest bridges to the smallest medical implants, sensors are everywhere, and for good reason: The ability to sense and monitor changes before they become problems can be both cost-saving and life-saving.

2 Jun 2021

Scientists test antibody-based therapy to treat Crimean-Congo hemorrhagic fever virus

Army scientists working as part of an international consortium have developed and tested an antibody-based therapy to treat Crimean-Congo hemorrhagic fever virus (CCHFV), which is carried by ticks and kills up to 60 percent of those infected.

2 Jun 2021

Novel antibody engineering approach

Scientists from the Johns Hopkins University School of Medicine, USA, have recently developed an Antibody Display technology by grafting the second extracellular domain of tetraspanin12 (Tspan12EC2) and the receptor-binding domain (RBD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein on the heavy chain complementarity-determining region 3 (CDR3).

2 Jun 2021

Researchers find natural metabolites help SARS-CoV-2 escape antibodies

An international team of scientists has identified a human molecule — biliverdin — as a potential severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) target. The binding of the heme metabolite to the N-terminal domain of SARS-CoV-2 is associated with the virus’s ability to dodge the immune system by suppressing antibody binding to the spike protein.

2 Jun 2021

Nanoscale coordination polymers show promise for efficient dopamine delivery in Parkinson's treatment

Parkinson's disease (PD) is a common neurodegenerative disorder caused by the death of dopaminergic neurons in a part of the brain (known as substantia nigra pars compacta), which leads to a deficit of dopamine (DA), one of the main neurotransmitters active in the central nervous system.

1 Jun 2021

Direct action of SARS-CoV-2 on organs may lead to exacerbated inflammatory response in pediatric patients

Besides common symptoms such as fever, cough and respiratory distress, some children have an atypical form of COVID-19 known as multisystem inflammatory syndrome in children (MIS-C), characterized by persistent fever and inflammation of several organs, such as the heart and intestines, as well as the lungs to a lesser extent.

1 Jun 2021

NIH launches first-in-human, Phase 1 trial assessing investigational nanoparticle influenza vaccine

A first-in-human, Phase 1 trial assessing the safety and immunogenicity of an investigational nanoparticle influenza vaccine designed to provide long-lasting protection against multiple flu virus strains has begun at the National Institutes of Health Clinical Center in Bethesda, Maryland.

1 Jun 2021

Small chip inserted under the skin may help predict the likelihood of recurrent stroke

For patients who have experienced certain common types of stroke, a small chip inserted under the skin may help physicians predict their likelihood of experiencing a second stroke, and therefore their likelihood of benefiting from preventive therapy.

1 Jun 2021

New project aims to develop technologies for quantifying cancer and viral biomarkers

Liquid biopsy, the detection of circulating disease biomarkers in bodily fluids such as blood, is a non-invasive method, alternative to tissue removal, which has taken important strides toward the implementation of personalized medicine, especially in the case of tumors and RNA-viruses.

1 Jun 2021

Malaria parasites may survive, replicate within the spleen of asymptomatic individuals, study suggests

Malaria, a disease caused mainly by the parasites Plasmodium falciparum and Plasmodium vivax, (P. vivax) is associated with over 400,000 deaths each year.

1 Jun 2021

Glycosylated hemoglobin can provide a useful estimate of atherosclerosis and cardiovascular events

The routine use of the glycosylated hemoglobin test to track blood sugar levels in the general population can identify individuals with more advanced atherosclerotic disease.

1 Jun 2021

Implantable device more effective at detecting atrial fibrillation than standard of care

A clinical trial examining the efficacy of two devices to monitor and detect atrial fibrillation (AF), or an irregular heartbeat, in ischemic stroke patients--one an implantable device that monitors over 12 months, the other an external device that monitors over a 30-day period--found the implantable device is more than three times more effective in detecting AF, and both are a significant improvement over the current standard of care in Alberta, Canada.

1 Jun 2021

Moffitt Cancer Center presents new data from dozens of clinical research studies at ASCO

Moffitt Cancer Center, a national leader in cancer care and research and the only National Cancer Institute-designated Comprehensive Cancer Center based in Florida, is presenting new data from dozens of clinical research studies at this year's American Society of Clinical Oncology (ASCO) Annual Meeting, the world's largest clinical cancer research meeting.

1 Jun 2021

NIH starts Phase 1/2 clinical trial evaluating mixed COVID-19 vaccine schedules

The National Institutes of Health has started a Phase 1/2 clinical trial in which adult volunteers who have been fully vaccinated against COVID-19 will receive booster doses of different COVID-19 vaccines to determine the safety and immunogenicity of mixed boosted regimens.

1 Jun 2021

The LUCA device shows high accuracy in thyroid cancer screening

Thyroid nodules are a common pathology having a prevalence of 19-76% when screened with ultrasound, with higher frequencies in women.

1 Jun 2021

Researchers receive $5 million NIH grant to reduce childhood obesity disparities

A research team led by the University of Minnesota Medical School has been awarded a $5 million grant from the National Institute of Health to conduct a clinical trial that hopes to identify the most effective approach to reduce racial and ethnic disparities in childhood obesity.

1 Jun 2021

Blood News and Research

Women who experience acute aortic dissection are more likely to die than men, shows study

Researchers identify new approach to clear toxic Huntingtin protein

Natural Killer cells acts as a potential target of immunotherapy, shows study

Positive COVID-19 screening test helps monitor respiration rate, blood-oxygen saturation at home

Revolutionary material senses and powers itself, may lead to new generation of living structures

Scientists test antibody-based therapy to treat Crimean-Congo hemorrhagic fever virus

Novel antibody engineering approach

Researchers find natural metabolites help SARS-CoV-2 escape antibodies

Nanoscale coordination polymers show promise for efficient dopamine delivery in Parkinson's treatment

Direct action of SARS-CoV-2 on organs may lead to exacerbated inflammatory response in pediatric patients

NIH launches first-in-human, Phase 1 trial assessing investigational nanoparticle influenza vaccine

Small chip inserted under the skin may help predict the likelihood of recurrent stroke

New project aims to develop technologies for quantifying cancer and viral biomarkers

Malaria parasites may survive, replicate within the spleen of asymptomatic individuals, study suggests

Glycosylated hemoglobin can provide a useful estimate of atherosclerosis and cardiovascular events

Implantable device more effective at detecting atrial fibrillation than standard of care

Moffitt Cancer Center presents new data from dozens of clinical research studies at ASCO

NIH starts Phase 1/2 clinical trial evaluating mixed COVID-19 vaccine schedules

The LUCA device shows high accuracy in thyroid cancer screening

Researchers receive $5 million NIH grant to reduce childhood obesity disparities

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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