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FDA grants Orphan Drug Designation to Myelo001 for treatment of Acute Radiation Syndrome

Myelo Therapeutics GmbH announced today that the US Food and Drug Administration has granted an Orphan Drug Designation to its orally applied new chemical entity Myelo001 for the treatment of Acute Radiation Syndrome.

25 Sep 2018

5 things to know about Trump’s new ‘public charge’ immigration proposal

A proposed rule from the White House would make it harder for legal immigrants to get green cards if they have received certain kinds of public assistance — including Medicaid, food stamps and housing subsidies. Green cards allow them to live and work permanently in the United States.

25 Sep 2018

Genervon reports new findings that drug candidate GM6 attenuates Alzheimer's disease in mice model

Following the closure of several research programs for Alzheimer's disease, in early 2018 the FDA issued a release entitled "Draft Guidance for Industry: Early Alzheimer's Disease: Developing Drugs for Treatment." Encouraged by the proposed changes in the new guidance, Genervon's research team reported new findings that its drug candidate GM6 attenuates Alzheimer's disease in an early AD transgenic APP mice model.

25 Sep 2018

Physical activity may have beneficial effects for people with rare Alzheimer's disease

For individuals carrying a genetic mutation that causes Alzheimer's disease, engaging in at least 2.5 hours of physical activity per week may have beneficial effects on markers of Alzheimer's disease brain changes and may delay cognitive decline, according to a new study available online by Alzheimer's & Dementia: The Journal of the Alzheimer's Association as an article in press, corrected proof.

25 Sep 2018

Benefit and harm of new screening program for depression still remain unclear

Almost 12% of all adults in Germany are diagnosed with depression at some point in their lives. The German Institute for Quality and Efficiency in Health Care investigated whether participants in a screening programme could have advantages or disadvantages if their general practitioner, for example, offers regular tests based on a questionnaire that can reveal signs of depression.

25 Sep 2018

Organs actively fighting back against autoimmune diseases, finds study

Organs affected by autoimmune disease could be fighting back by "exhausting" immune cells that cause damage using methods similar to those used by cancer cells to escape detection, according to a study by researchers at the University of Pittsburgh School of Medicine published today in the Journal of Clinical Investigation.

25 Sep 2018

Hybrid theranostic complex shows high therapeutic efficacy against tumor cells

Emerging cancer nanotechnology enables target-delivery of substantial payloads of drugs to cancer sites with concomitant reduction of side-effects due to the lesser accumulation in the critical organs.

25 Sep 2018

Study: Women with non-small cell lung cancers live longer than their male counterparts

Women diagnosed with non-small cell lung cancers live longer than their male counterparts, according to results of a SWOG study presented today by Kathy Albain, MD, the Huizenga Family Endowed Chair in Oncology Research at Loyola University Chicago Stritch School of Medicine, at the International Association for the Study of Lung Cancer's 19th World Conference on Lung Cancer in Toronto, Ontario, Canada.

25 Sep 2018

Common painkiller not effective in controlling chronic pain after traumatic nerve injury

A new study out today in the Journal of Neurology finds that pregabalin is not effective in controlling the chronic pain that sometimes develops following traumatic nerve injury.

25 Sep 2018

Researchers reassess negative pressure wound therapy as its benefit and harm remain unclear

About one decade after its first benefit assessment of negative pressure wound therapy, the German Institute for Quality and Efficiency in Health Care is reassessing this treatment method. However, then as now, its benefit and harm are unclear.

25 Sep 2018

Genomic ‘islands’ evolved from viruses can be converted into ‘anti-bacterial drones’

Genomic "islands" that evolved from viruses can be converted into "drones" that disable Staphylococcus aureus, bacteria that are often resistant to antibiotics and pose a threat to safe hospital care, a new study finds.

25 Sep 2018

Phase 1 and 2 clinical trials of entrectinib drug in ROS1-positive NSCLC show promising results

Results of phase 1 and phase 2 clinical trials of the drug entrectinib in ROS1-positive non-small cell lung cancer presented on the press program of the International Association for the Study of Lung Cancer 19th World Conference on Lung Cancer show a response rate of 77.4 percent for 53 patients evaluable for response, with median duration of response of 24.6 months.

25 Sep 2018

Clinical trial investigators found non-compliant with requirement to report results on EU register

According to EU legislation, clinical trials must be prospectively registered in the European Union Clinical Trials Register and the main results must be reported there one year after completion of the trial. This information is thus publicly available.

25 Sep 2018

Lung cancer patients treated with invasive surgery more likely to become chronic opioid users

Patients treated with more-invasive surgical techniques for a type of early-stage lung cancer are more likely to become chronic opioid users than patients treated with minimally invasive surgery, highlighting the need for additional research into how pain management after surgery might be a contributing factor to the opioid addiction crisis, according to a study published in JAMA Oncology in September.

24 Sep 2018

TU Wien develops new remedy for celiac disease

Celiac disease is a fairly common disease, affecting one to two percent of the European population. It is expressed as a hypersensitivity to gluten, a protein found in cereals such as wheat, barley or rye.

24 Sep 2018

Alexion announces positive results from Phase 3 PREVENT study of Soliris in patients with NMOSD

Alexion Pharmaceuticals, Inc. today announced positive topline results from the Phase 3 PREVENT study of Soliris in patients with anti-aquaporin-4 auto antibody-positive neuromyelitis optica spectrum disorder.

24 Sep 2018

Researchers analyze response to combination immunotherapy for patients with rare skin cancer

Harnessing the immune system to treat cancer shows great promise in some patients, but for many, the response does not last long-term.

24 Sep 2018

Columbia University announces winners of 2018 Louisa Gross Horwitz Prize

Columbia University has decided to award the Louisa Gross Horwitz Prize 2018.

24 Sep 2018

New nanoplatform technology may reverse drug-resistance in renal cell carcinoma

A research team led by Arun Iyer, Ph.D., assistant professor of pharmaceutical sciences in the Eugene Applebaum College of Pharmacy and Health Sciences at Wayne State University, has developed a nanoplatform technology that works in combination with existing chemotherapeutic drugs that may reverse drug-resistance in renal cell carcinoma.

24 Sep 2018

Children of mothers using cannabis may start using it at an earlier age, finds study

When mothers use marijuana during the first 12 years of their child's life, their cannabis-using children are more likely to start at an earlier age than children of non-using mothers, according to a new study from the Harvard T.H. Chan School of Public Health published in the American Journal of Preventive Medicine.

24 Sep 2018

Drugs News and Research

FDA grants Orphan Drug Designation to Myelo001 for treatment of Acute Radiation Syndrome

5 things to know about Trump’s new ‘public charge’ immigration proposal

Genervon reports new findings that drug candidate GM6 attenuates Alzheimer's disease in mice model

Physical activity may have beneficial effects for people with rare Alzheimer's disease

Benefit and harm of new screening program for depression still remain unclear

Organs actively fighting back against autoimmune diseases, finds study

Hybrid theranostic complex shows high therapeutic efficacy against tumor cells

Study: Women with non-small cell lung cancers live longer than their male counterparts

Common painkiller not effective in controlling chronic pain after traumatic nerve injury

Researchers reassess negative pressure wound therapy as its benefit and harm remain unclear

Genomic ‘islands’ evolved from viruses can be converted into ‘anti-bacterial drones’

Phase 1 and 2 clinical trials of entrectinib drug in ROS1-positive NSCLC show promising results

Clinical trial investigators found non-compliant with requirement to report results on EU register

Lung cancer patients treated with invasive surgery more likely to become chronic opioid users

TU Wien develops new remedy for celiac disease

Alexion announces positive results from Phase 3 PREVENT study of Soliris in patients with NMOSD

Researchers analyze response to combination immunotherapy for patients with rare skin cancer

Columbia University announces winners of 2018 Louisa Gross Horwitz Prize

New nanoplatform technology may reverse drug-resistance in renal cell carcinoma

Children of mothers using cannabis may start using it at an earlier age, finds study

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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