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Maintenance TKI therapy 'feasible' for high-risk CML patients after allogeneic HSCT

Patients with high-risk chronic myeloid leukaemia who undergo allogeneic haematopoietic stem cell transplantation may benefit from continuing with tyrosine kinase inhibitor therapy, US clinicians believe.

15 Jun 2016

Long-term dasatinib findings support first-line use in CML

Final DASISION study findings confirm dasatinib to be an effective, long-term treatment for patients with a new diagnosis of chronic phase-chronic myeloid leukaemia.

15 Jun 2016

Researchers explore why women have ubiquitous survival advantage than men

Women live longer than men. This simple statement holds a tantalizing riddle that Steven Austad, Ph.D., and Kathleen Fischer, Ph.D., of the University of Alabama at Birmingham explore in a perspective piece published in Cell Metabolism on June 14.

15 Jun 2016

FDA approves novel stomach-draining device to treat obesity

The U.S. Food and Drug Administration today approved a new obesity treatment device that uses a surgically-placed tube to drain a portion of the stomach contents after every meal.

15 Jun 2016

Cranberries can reduce symptomatic UTIs and avoid chronic suppressive antibiotics

Today leading experts on infectious disease and urinary tract infections (UTIs) will gather in London to discuss the alarming state of antibiotic resistance, and present findings from a landmark study that conclusively shows that cranberries can be a nutritional approach to reducing symptomatic UTIs, and as a result, may be a useful strategy to decrease worldwide use of antibiotics.

15 Jun 2016

Mayo researchers develop extremely precise assay to measure age-associated changes in GDF11

Researchers at Mayo Clinic have developed an accurate way to measure a circulating factor, called GDF11, to better understand its potential impact on the aging process.

15 Jun 2016

MicroRNA plays role in blocking development of arterial thrombosis

The dangers of arterial thrombosis - the formation of blood clots that can block arteries and cause illness or death - can escalate through a vicious cycle of coagulation and inflammation.

15 Jun 2016

Blood pressure medications can lower stroke, heart attack risk in patients with end-stage renal disease

Two classes of blood pressure medications, angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs), are associated with a 16% lower risk of strokes, heart attacks and death in patients with end-stage renal disease who are undergoing peritoneal dialysis, a new study in the journal, Nephrology Dialysis Transplantation, reports.

15 Jun 2016

New technique may help replace brain cells, restore memory

Although brains—even adult brains—are far more malleable than we used to think, they are eventually subject to age-related illnesses, like dementia, and loss of cognitive function.

15 Jun 2016

Study characterizes benefits of over-the-counter sleep aid

New research shows that an over-the-counter sleep aid helps people suffering from occasional sleep difficulties fall asleep in less than 20 minutes, on average, and improves their reported quality of sleep.

15 Jun 2016

POLYCARE project aims to develop integrated home care model for older chronic patients

Fraunhofer FIT in St. Augustin and the University Hospital of Bonn are among the partners in the new European POLYCARE project, which is developing an integrated care system that will improve the care of chronic patients at home. The University Hospital of Bonn will be one of three pilot sites for the project.

15 Jun 2016

Primary care-based program can help improve assessment and treatment of asthma in children

An innovative primary care-based asthma program improves identification of poorly controlled asthma among children and enhances treatment plans, compared to care provided during routine office visits, according to research published in the current edition of the Journal of Asthma.

15 Jun 2016

CHLA study provides novel insights into the brain mechanisms linked to Prader-Willi syndrome

A study published in the journal Human Molecular Genetics by researchers at Children's Hospital Los Angeles provides novel insights into the brain mechanisms underlying the insatiable hunger and subsequent obesity in patients with Prader-Willi syndrome.

15 Jun 2016

New survey reveals more than half of patients prescribed opioids have leftover pills

In the midst of an epidemic of prescription painkiller addiction and overdose deaths, a new Johns Hopkins Bloomberg School of Public Health survey suggests that more than half of patients prescribed opioids have leftover pills -- and many save them to use later.

14 Jun 2016

Poor physical fitness, passive hobbies may increase pain conditions in children

Poor physical fitness and sedentary behaviour are linked to increased pain conditions in children as young as 6-8 years old, according to the Physical Activity and Nutrition in Children Study ongoing at the University of Eastern Finland. The findings were published in the Journal of Pain.

14 Jun 2016

Stroke can cause long-term damage to blood-spinal cord barrier, study finds

A team of researchers at the University of South Florida investigating the short and long-term effects of ischemic stroke in a rodent model has found that stroke can cause long-term damage to the blood-spinal cord barrier (BSCB), creating a "toxic environment" in the spinal cord that might leave stroke survivors susceptible to motor dysfunction and disease pathology.

14 Jun 2016

Young cancer survivors more likely to be current cigarette smokers

Researchers at The University of Texas Medical Branch at Galveston have found that cancer survivors who were diagnosed at adolescent and young adult ages are more likely to be current cigarette smokers than people who have not had cancer. The findings of this study are currently available in Cancer.

14 Jun 2016

Chronic sleep restriction may impair performance in healthy, elite atheletes

A new study found that chronic sleep restriction negatively affects athletic performance.

14 Jun 2016

Clinical trial to test efficacy of new drug for chronic cough

The National Institute for Health Research has today announced its participation in a clinical trial to test a promising new treatment for chronic cough. If approved, this would be the first new cough drug in 50 years and offer hope to the millions of people living with chronic cough for whom few, if any, effective treatments exist.

14 Jun 2016

GPCR-Gβγ inhibition therapy could prevent chronic and acute kidney damage in heart failure patients

A study in the Journal of the American Society of Nephrology suggests a new therapeutic approach to treat the development of chronic kidney disease secondary to chronic heart failure, known as cardiorenal syndrome type 2.

14 Jun 2016

Chronic News and Research

Maintenance TKI therapy 'feasible' for high-risk CML patients after allogeneic HSCT

Long-term dasatinib findings support first-line use in CML

Researchers explore why women have ubiquitous survival advantage than men

FDA approves novel stomach-draining device to treat obesity

Cranberries can reduce symptomatic UTIs and avoid chronic suppressive antibiotics

Mayo researchers develop extremely precise assay to measure age-associated changes in GDF11

MicroRNA plays role in blocking development of arterial thrombosis

Blood pressure medications can lower stroke, heart attack risk in patients with end-stage renal disease

New technique may help replace brain cells, restore memory

Study characterizes benefits of over-the-counter sleep aid

POLYCARE project aims to develop integrated home care model for older chronic patients

Primary care-based program can help improve assessment and treatment of asthma in children

CHLA study provides novel insights into the brain mechanisms linked to Prader-Willi syndrome

New survey reveals more than half of patients prescribed opioids have leftover pills

Poor physical fitness, passive hobbies may increase pain conditions in children

Stroke can cause long-term damage to blood-spinal cord barrier, study finds

Young cancer survivors more likely to be current cigarette smokers

Chronic sleep restriction may impair performance in healthy, elite atheletes

Clinical trial to test efficacy of new drug for chronic cough

GPCR-Gβγ inhibition therapy could prevent chronic and acute kidney damage in heart failure patients

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