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Nonhuman primate study helps explain how stem cell transplantation can kill HIV virus

New animal research is helping explain why at least five people have become HIV-free after receiving a stem cell transplant.

25 May 2023

First-in-human nanoparticle HIV vaccine induces broad and publicly targeted helper T cell responses

Researchers from Fred Hutchinson Cancer Center in Seattle, Scripps Research in La Jolla, California, IAVI and other collaborating institutions have characterized robust T-cell responses in volunteers participating in the IAVI G001 Phase 1 clinical trial to test the safety and immune response of a self-assembling nanoparticle HIV vaccine.

25 May 2023

$Is prediabetes associated with increased fracture risk among midlife women?$

Is prediabetes associated with increased fracture risk among midlife women?

Studying the correlation between prediabetes before the menopause and increased fracture risk.

25 May 2023

Precision nutrition and the gut microbiome: the impact of blueberries

Researchers explored the impacts of precision nutrition on gut microbiome variation.

25 May 2023

Looking at cancer drugs to help put the brakes on classic indicators of aging

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

Scientists to discuss the latest cancer therapies, advances in PSMA PET scans and many more at ASCO

Physicians and scientists from the UCLA Jonsson Comprehensive Cancer Center will discuss the latest research and clinical trial results on combination therapies for breast cancer, a potential new treatment for patients with recurrent glioma, and advances in PSMA PET guided radiotherapy for patients with prostate cancer, among other topics, at the American Society of Clinical Oncology's annual meeting.

23 May 2023

$OST performs better than FRAX in determining osteoporotic fracture risk in younger postmenopausal women$

OST performs better than FRAX in determining osteoporotic fracture risk in younger postmenopausal women

The commonly used Fracture Risk Assessment Tool (FRAX), which includes self-identified race and ethnicity information, and the Osteoporosis Self-Assessment Tool (OST), which does not, had suboptimal performance in determining major osteoporotic fracture risk across racial/ethnic categories in younger postmenopausal women.

22 May 2023

Women who experience adverse pregnancy outcomes have higher stroke risk

Investigators from the Smidt Heart Institute at Cedars-Sinai found that women who experience an adverse pregnancy outcome - such as gestational hypertension, preeclampsia or preterm birth - have a higher risk of developing stroke in their lifetime, and at a younger age.

22 May 2023

Researchers receive $2.3 million to continue development of a new ‘glyco-immune’ checkpoint inhibitor

Researchers from Rice University and Baylor College of Medicine are hoping a first-of-its-kind "glyco-immune" checkpoint inhibitor could be the key to stopping bone cancer metastasis for breast cancer survivors.

19 May 2023

NYU Grossman School of Medicine celebrates achievements of new doctors at 2023 graduation ceremony

NYU Grossman School of Medicine celebrated the achievements of 111 new doctors at its graduation ceremony on Wednesday, May 17, at Lincoln Center's Alice Tully Hall.

18 May 2023

How the gut microbiome supports iron uptake by intestinal regulatory T-cells

Research paper discusses the relationship between iron deficiencies and immune tolerance in patients with inflammatory bowel disease. The study shows that high cellular iron levels fostered by pentanoate, a short-chain fatty acid produced by intestinal microbiota, are necessary for the homeostasis of regulatory T cells in the intestine, and iron deficiencies in Treg can result in lethal autoimmune disease.

17 May 2023

Amputations for combat-related injuries may negatively affect bone mass, study suggests

Combat-related injuries to bone are common in military personnel and can lead to pain and disability.

17 May 2023

$Bone breakthrough: Researchers develop 'skeletal age' tool to predict mortality risk after fractures$

Bone breakthrough: Researchers develop 'skeletal age' tool to predict mortality risk after fractures

Fragility fractures are tied to elevated mortality risk, yet often overlooked in doctor-patient discussions. A new concept of 'Skeletal Age' is proposed to convey both fracture risk and associated mortality for individuals.

17 May 2023

Mast cells play a crucial role in the development of chronic myeloid leukemia

Chronic myeloid leukemia (CML) is a type of blood cancer that arises from malignant changes in blood-forming cells of the bone marrow.

16 May 2023

Young adult cancer survivors at higher risk of heart failure when treated with anthracyclines

Imagine surviving cancer only to learn the drug that saved your life has introduced a completely different health risk: heart failure.

16 May 2023

Researchers report the role of RNA-binding protein Msi 1 to maintain breast cancer stem cells

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 9, entitled, "Increased expression of musashi 1 on breast cancer cells has implication to understand dormancy and survival in bone marrow."

16 May 2023

Cancer patients can initiate SARS-CoV-2 vaccination three months after bone marrow transplant

Patients with cancer whose immune systems are being supported or rebuilt by bone marrow transplantation should begin receiving vaccines for protection against SARS-CoV-2 three months post-transplant, according to a large, prospective, observational study led collaboratively by the Center for International Blood and Marrow Transplant Research, the Blood & Marrow Transplant Clinical Trials Network and Fred Hutchinson Cancer Center.

16 May 2023

Injectable fatty acid copolymer ARA 3000 BETA shows therapeutic potential in treating osteoarthritis

Researchers examined the therapeutic potential of ARA 3,000 BETA for treating osteoarthritis.

16 May 2023

Obesity strongly associated with clonal hematopoiesis of indeterminate potential

Indiana University School of Medicine researchers studying clonal hematopoiesis of indeterminate potential (CHIP), a blood condition that may increase the risk of blood cancer, discovered that obesity was strongly associated with the condition.

16 May 2023

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Researchers at Baylor College of Medicine/Texas Children's Cancer Center and collaborating institutions report interim results from a first-in-human phase 1 clinical trial evaluating the safety, antitumor activity and immunological characteristics of a genetically engineered natural killer T (NKT) cell immunotherapy for neuroblastoma, a childhood tumor that most commonly arises in the adrenal gland.

15 May 2023

Bone News and Research

Nonhuman primate study helps explain how stem cell transplantation can kill HIV virus

First-in-human nanoparticle HIV vaccine induces broad and publicly targeted helper T cell responses

Is prediabetes associated with increased fracture risk among midlife women?

Precision nutrition and the gut microbiome: the impact of blueberries

Looking at cancer drugs to help put the brakes on classic indicators of aging

Scientists to discuss the latest cancer therapies, advances in PSMA PET scans and many more at ASCO

OST performs better than FRAX in determining osteoporotic fracture risk in younger postmenopausal women

Women who experience adverse pregnancy outcomes have higher stroke risk

Researchers receive $2.3 million to continue development of a new ‘glyco-immune’ checkpoint inhibitor

NYU Grossman School of Medicine celebrates achievements of new doctors at 2023 graduation ceremony

How the gut microbiome supports iron uptake by intestinal regulatory T-cells

Amputations for combat-related injuries may negatively affect bone mass, study suggests

Bone breakthrough: Researchers develop 'skeletal age' tool to predict mortality risk after fractures

Mast cells play a crucial role in the development of chronic myeloid leukemia

Young adult cancer survivors at higher risk of heart failure when treated with anthracyclines

Researchers report the role of RNA-binding protein Msi 1 to maintain breast cancer stem cells

Cancer patients can initiate SARS-CoV-2 vaccination three months after bone marrow transplant

Injectable fatty acid copolymer ARA 3000 BETA shows therapeutic potential in treating osteoarthritis

Obesity strongly associated with clonal hematopoiesis of indeterminate potential

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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