Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Drug that improves blood flow in damaged heart may be possible treatment option for TNBC

Researchers are looking at a drug once used to improve blood flow in damaged hearts in thousands of patients as a possible treatment option for triple negative breast cancer (TNBC).

6 Jan 2017

Targeting Legumain could be promising strategy for treatment of cancer

Legumain (LGMN), or asparaginyl endopeptidase, is a newly identified lysosomal cysteine protease.

3 Jan 2017

Columbia University Medical Center to evaluate Biocept's Target Selector platform to diagnose LM in breast cancer patients

Biocept, Inc., a leading commercial provider of clinically actionable liquid biopsy tests designed to improve the outcomes of cancer patients, announces that Columbia University Medical Center will conduct a study to evaluate the clinical utility of the Company's Target Selector™ platform to diagnose leptomeningeal metastases (LM) in patients with breast cancer.

30 Dec 2016

IQWiG investigates benefit of biomarker tests to support decision on adjuvant chemotherapy

The German Institute for Quality and Efficiency in Health Care (IQWiG) investigated the benefit of biomarker tests to support the decision for or against adjuvant systemic chemotherapy in certain breast cancer patients, that is, women with primary hormone receptor-positive, HER2-negative breast cancer and up to 3 affected lymph nodes.

30 Dec 2016

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutchinson Cancer Research Center announced its first-ever grants from its newly established Evergreen Fund to spur researchers' efforts to advance bold ideas toward creating or partnering with a commercial entity.

28 Dec 2016

New discovery could lead to effective drugs to prevent excessive lymphatic growth in cancer

Cancer cells spread to other sites in the body through promoting the growth of new 'roads' to travel on.

27 Dec 2016

Special Issue on digestive cancers offers five articles from experts in Latin America

ecancermedicalscience has published a new Special Issue on digestive cancers in Latin America, bringing together five articles from experts in the region.

21 Dec 2016

Researcher develops new method to accurately identify elusive molecules

Among the most important molecules in the living world are sugars or carbohydrates, which play a vital role in life processes. Sugars provide the main source of fuel for the body, protect muscles from damage and contribute to the immune response.

21 Dec 2016

Research sheds new light on key drivers of cancer metastasis

Latest research from New Zealand's University of Otago is shedding new light on why and how cancer cells spread from primary tumours to other parts of the body. This phenomenon - known as metastasis - causes about 90 per cent of all cancer deaths.

21 Dec 2016

Scientists unveil role of NOX4 protein as inhibitor of invasion and metastasis of liver tumor cells

Researchers of the TGF-beta and Cancer group of Bellvitge Biomedical Research Institute, in collaboration with King's College London, have unveiled the role of NADPH oxidase NOX4 as an inhibitor of the epithelial-amoeboid transition, a process that contributes to the migration and invasion of tumor cells.

20 Dec 2016

CNIC scientists reveal fundamental role of hypoxia response in correct formation of the heart

Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III have demonstrated the fundamental role of the hypoxia response in the correct formation of the heart ventricles.

19 Dec 2016

Scientists identify novel protein pathway across cancer types that fuels tumor progression

Scientists at The Wistar Institute have identified a novel protein pathway across several types of cancer that controls how tumor cells acquire the energy necessary for movement, invasion and metastasis.

19 Dec 2016

Researchers identify attractive drug candidate to target glioma tumors

In a paper published today in Cancer Research, researchers: 1) identify a biomarker enzyme associated with aggressive glioma brain tumors, 2) reveal the regulatory mechanism for that enzyme, and 3) demonstrate potent efficacy, using a mouse model of glioma, for a small molecule inhibitor they have developed.

16 Dec 2016

WPI researchers develop chip to trap and identify metastatic cancer cells in blood

A chip developed by mechanical engineers at Worcester Polytechnic Institute can trap and identify metastatic cancer cells in a small amount of blood drawn from a cancer patient.

16 Dec 2016

Calcium channel blockers may be effective drugs against cancer metastasis

Researchers at the University of Turku, Finland have identified a new way of blocking the spread of cancer. Calcium channel blockers, which are used to lower blood pressure, block breast and pancreatic cancer invasion by inhibiting cellular structures.

16 Dec 2016

Research findings could offer novel approach for cancer prevention in women with BRCA1 mutations

Women with inherited mutations in the BRCA1 or BRCA2 genes are at substantially higher risk of breast cancer. For these women, effective prevention strategies are their best hope to reduce their breast cancer risk.

16 Dec 2016

Image-guided percutaneous needle biopsies after NST identify breast cancer patients who achieve pCR

In a pilot study conducted at The University of Texas MD Anderson Cancer Center, image-guided biopsies identified select breast cancer patients who achieved pathologic complete response (pCR) after chemotherapy and/or targeted therapy, neoadjuvant systemic therapy (NST).

9 Dec 2016

Human migration study reveals new insights into cancer metastasis

What could cancer cells and drug-resistant bacteria possibly have in common with Stone Age settlers of the Americas? They're all migratory, and at one time or other, each finds the going a bit easier in a specific direction.

9 Dec 2016

Scientists discover truncated p53 proteins that promote cancer growth and metastasis

Discovered in the 1970s, tumor suppressors are among the most important proteins in the body.

8 Dec 2016

Brain metastasis persists in women with HER2-positive breast cancer despite new targeted therapies

While new targeted treatments developed across the past two decades have led to dramatic survival improvements for women with HER2-positive metastatic breast cancer, University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators report that rates of breast cancer brain metastasis for women with this disease have not substantially declined.

7 Dec 2016

Metastasis News and Research

Further Reading

Drug that improves blood flow in damaged heart may be possible treatment option for TNBC

Targeting Legumain could be promising strategy for treatment of cancer

Columbia University Medical Center to evaluate Biocept's Target Selector platform to diagnose LM in breast cancer patients

IQWiG investigates benefit of biomarker tests to support decision on adjuvant chemotherapy

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

New discovery could lead to effective drugs to prevent excessive lymphatic growth in cancer

Special Issue on digestive cancers offers five articles from experts in Latin America

Researcher develops new method to accurately identify elusive molecules

Research sheds new light on key drivers of cancer metastasis

Scientists unveil role of NOX4 protein as inhibitor of invasion and metastasis of liver tumor cells

CNIC scientists reveal fundamental role of hypoxia response in correct formation of the heart

Scientists identify novel protein pathway across cancer types that fuels tumor progression

Researchers identify attractive drug candidate to target glioma tumors

WPI researchers develop chip to trap and identify metastatic cancer cells in blood

Calcium channel blockers may be effective drugs against cancer metastasis

Research findings could offer novel approach for cancer prevention in women with BRCA1 mutations

Image-guided percutaneous needle biopsies after NST identify breast cancer patients who achieve pCR

Human migration study reveals new insights into cancer metastasis

Scientists discover truncated p53 proteins that promote cancer growth and metastasis

Brain metastasis persists in women with HER2-positive breast cancer despite new targeted therapies

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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