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RNA editing enzyme ADAR1 may play role in regeneration of leukemia stem cells

Cancer stem cells are like zombies — even after a tumor is destroyed, they can keep coming back. These cells have an unlimited capacity to regenerate themselves, making more cancer stem cells and more tumors.

10 Jun 2016

Utah researchers find way to use power of protease to destroy budding AIDS virus

When new AIDS virus particles bud from an infected cell, an enzyme named protease activates to help the viruses mature and infect more cells. That's why modern AIDS drugs control the disease by inhibiting protease.

10 Jun 2016

New study finds underutilization of PR therapy among older COPD patients

A new study from The University of Texas Medical Branch at Galveston investigating trends on the use of pulmonary rehabilitation therapy among older adults with chronic obstructive pulmonary disease found that this therapy was underutilized, despite its health benefits and cost effectiveness.

10 Jun 2016

Smoking, obesity lower chances of achieving sustained remission in early RA patients

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that the likelihood of achieving sustained remission in early rheumatoid arthritis (RA) is significantly lower in patients who smoke and who are obese.

10 Jun 2016

New RNA aptamer can prevent pathogenic protein misfolding

Several diseases occur when mutations cause misfolding of proteins. These include "serpinopathies" which is a group of rare heritable diseases. They are caused by mutations of so-called "serpin" inhibitors of proteolytic enzymes involved in blood coagulation, tissue remodeling, and other important physiological functions.

10 Jun 2016

Women with SLE may have increased cervical cancer risk

The results of a study presented today at the European League Against Rheumatism Annual Congress found a doubled risk of pre-malignant cervical changes, and potentially also an increased risk of cervical cancer, among women with Systemic Lupus Erythematosus (SLE) compared to the general female population.

10 Jun 2016

BNPs have potential to enable early diagnosis, long-term treatment of RA with minimal side effects

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that tiny particles made of a biodegradable polymer (BNPs -- biodegradable polymer nanoparticles) have the potential to enable early detection and efficient long-term treatment of rheumatoid arthritis (RA), with minimal side effects.

10 Jun 2016

Type 1 diabetes occurs more frequently in patients with JIA

The results of a study involving more than 9,000 patients, presented today at the European League Against Rheumatism Annual Congress showed that Type 1 diabetes occurs significantly more frequently in patients with Juvenile Inflammatory Arthritis (JIA) than in the general population.

10 Jun 2016

Air pollution exposure may have direct role in triggering lupus among children and adolescents

The results of a study presented today at the European League Against Rheumatism Annual Congress show for the first time that an individual's exposure to air pollution may have a direct role in triggering disease activity as well as airway inflammation in children and adolescents with Systemic Lupus Erythematosus (SLE).

10 Jun 2016

Childhood exposure to chronic parental domestic violence linked to suicide attempts among adults

A new study by the University of Toronto, found the lifetime prevalence of suicide attempts among adults who had been exposed to chronic parental domestic violence during childhood was 17.3% compared to 2.3% among those without this childhood adversity.

10 Jun 2016

New drug for chronic migraine may reduce headache hours in few days

A new drug to prevent migraine was associated with fewer headache hours for people with chronic migraine within three to seven days after the first injection, according to a study published in the June 8, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

9 Jun 2016

Standard and intensive blood pressure treatments equally effective in controlling acute intracerebral hemorrhage

An international stroke study found that standard and intensive blood pressure treatments were equally effective in the emergency treatment of acute intracerebral hemorrhage, a type of stroke caused by bleeding into the brain.

9 Jun 2016

Simple blood test can help track rising levels of eosinophils linked to regrowth of sinus polyps

In an effort to identify a simple, reliable way to track the course of nasal polyps in chronic sinus disease, Johns Hopkins Medicine researchers say they've linked rising levels of immune system white blood cells, called eosinophils, with regrowth of polyps removed by surgery.

9 Jun 2016

Chronic News and Research

RNA editing enzyme ADAR1 may play role in regeneration of leukemia stem cells

Utah researchers find way to use power of protease to destroy budding AIDS virus

New study finds underutilization of PR therapy among older COPD patients

Smoking, obesity lower chances of achieving sustained remission in early RA patients

New RNA aptamer can prevent pathogenic protein misfolding

Women with SLE may have increased cervical cancer risk

BNPs have potential to enable early diagnosis, long-term treatment of RA with minimal side effects

Type 1 diabetes occurs more frequently in patients with JIA

Air pollution exposure may have direct role in triggering lupus among children and adolescents

Childhood exposure to chronic parental domestic violence linked to suicide attempts among adults

New drug for chronic migraine may reduce headache hours in few days

Standard and intensive blood pressure treatments equally effective in controlling acute intracerebral hemorrhage

Simple blood test can help track rising levels of eosinophils linked to regrowth of sinus polyps

Metabolite of oral DMF drug for multiple sclerosis appears to slow onset of Parkinson's disease

Age may play major role in cell's ability to respond to physical exercise

Migraine drug has quick onset of action

Yale researchers identify mechanisms responsible for human egg aging

Study finds differences in hospitalization trends for gout and rheumatoid arthritis

Novel enzyme immunoassay helps diagnose HCV infection in one simple step

Chronic marijuana use can interrupt the brain's natural reward processes

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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