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Novel treatment for hairy cell leukemia approved by FDA

The U.S. Food and Drug Administration today approved Lumoxiti (moxetumomab pasudotox-tdfk) injection for intravenous use for the treatment of adult patients with relapsed or refractory hairy cell leukemia (HCL) who have received at least two prior systemic therapies, including treatment with a purine nucleoside analog.

14 Sep 2018

Is ‘precision medicine’ the answer to cancer? Not precisely.

Facing incurable breast cancer at age 55, MaryAnne DiCanto put her faith in "precision medicine" — in which doctors try to match patients with drugs that target the genetic mutations in their tumors. She underwent repeated biopsies to identify therapies that might help.

13 Sep 2018

Study: Poor older Americans most likely to rely on prescription opioids

Among older Americans, the poorest are the most likely to have used prescription opioids, according to a University at Buffalo study providing new insights into unexplored contours of the opioid crisis.

12 Sep 2018

Study provides complete picture of HPV virus-head and neck cancer connections

Human papillomavirus is widely known to cause nearly all cases of cervical cancer. However, you might not know that HPV also causes 70 percent of oropharyngeal cancer, a subset of head and neck cancers that affect the mouth, tongue, and tonsils.

12 Sep 2018

Johns Hopkins scientists successfully perform 3D personalized virtual simulations of the heart

In a proof of concept study, scientists at Johns Hopkins report they have successfully performed 3D personalized virtual simulations of the heart to accurately identify where cardiac specialists should electrically destroy cardiac tissue to stop potentially fatal irregular and rapid heartbeats in patients with scarring in the heart.

12 Sep 2018

Sugar pills may help treat certain chronic pain patients

Someday doctors may prescribe sugar pills for certain chronic pain patients based on their brain anatomy and psychology. And the pills will reduce their pain as effectively as any powerful drug on the market, according to new research.

12 Sep 2018

Drug combination targets pre-leukemia stem cells

Your body's blood cells are manufactured by hematopoietic stem cells in bone marrow. But just as regular, mature cells can become cancerous, so too can stem cells.

12 Sep 2018

Screening does not reduce breast cancer mortality

Fewer and fewer women die from breast cancer in recent years but, surprisingly, the decline is just as large in the age groups that are not screened. The decline is therefore due to better treatment and not screening for breast cancer.

12 Sep 2018

Cocaine-addicted rats show long-lasting increases in number of orexin neurons

A study in cocaine-addicted rats reports long-lasting increases in the number of neurons that produce orexin—a chemical messenger important for sleep and appetite—that may be at the root of the addiction.

12 Sep 2018

Delayed childbearing plays role in increasing number of multiple births

Starting in the 1980s, the number of multiple births -- twins, triplets, quadruplets and quintuplets -- steadily increased from about 20 sets per 1,000 live births to almost 35 sets per 1,000 live births in the 2010s.

12 Sep 2018

Scientists identify how viral protein promotes fatal disease caused by Nipah and Hendra viruses

Researchers have identified how a viral protein, which plays a major role in causing deadly Nipah and Hendra virus infections, targets a critical function in human cells to suppress immune responses and promote fatal disease.

12 Sep 2018

Study uncovers four neuron types in the peripheral auditory system

Researchers at Karolinska Institutet have identified four types of neurons in the peripheral auditory system, three of which are new to science.

12 Sep 2018

Doctor to the stars disciplined over use of controversial menopause therapy

In a conversation with Sarah “Fergie” Ferguson, the Duchess of York, that aired on the Oprah Winfrey Network, Dr. Prudence Hall said age isn't what determines health and vitality.

12 Sep 2018

PAREXEL launches Patient Innovation Center to improve drug development process

PAREXEL International Corporation, a leading innovator of global biopharmaceutical services, today announced the launch of its Patient Innovation Center.

From Parexel 12 Sep 2018

Researchers design new medicine to treat highly aggressive pancreatic cancer

A treatment for highly aggressive and commonly fatal pancreatic cancer is being developed, reports a University of Houston researcher who has designed a new medicine that can inhibit two of the major pathways of the deadly disease.

12 Sep 2018

Researchers untangle mysteries of 'evil' protein in ER-positive breast cancer

Breast cancer is one of the most common cancers in the United States, striking 1 out of 8 women. About 80 percent of all breast cancers are estrogen receptor-positive, in which cancer growth is fueled by estrogen.

12 Sep 2018

Stimuli-responsive nanoparticles can specifically target infections to prevent spread of bacteria

Current WSU research shows stimuli-responsive nanoparticles can specifically target infections to simultaneously prevent the spread of bacteria and reduce the inflammation it causes.

12 Sep 2018

Clinical trial begins to find better treatment for chronic cases of PKDL in Africa

A clinical trial to find a better treatment for severe or chronic cases of post kala-azar dermal leishmaniasis (PKDL) in Africa has begun in Dooka, Sudan.

12 Sep 2018

Protein involved in milk production appears to stimulate growth and spread of breast cancer

VCU Massey Cancer Center researchers have identified a protein involved in milk production that stimulates the growth and spread of breast cancer and could ultimately serve as a target for novel therapies to treat breast cancer.

12 Sep 2018

Administering tPA depending on location of clot can be as effective as thrombectomy

There are two main treatments for stroke caused by a clot in a blood vessel in the brain. One treatment, mechanical thrombectomy, involves pulling the clot out with a specialized catheter that is inserted into the artery in the groin and guided by imaging to the clot.

12 Sep 2018