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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Researchers uncover new mechanism for designing antiviral drugs for dengue virus

A multidisciplinary team from The University of Texas Medical Branch at Galveston has uncovered a new mechanism for designing antiviral drugs for dengue virus. The study is currently available in Proceedings of the National Academy of Sciences.

14 Jul 2020

People with accelerated biological age at increased risk of COVID-19 symptom severity and mortality

Now, a new study published on the preprint server medRxiv in July 2020 discusses the explanation in terms of the biological aging markers in patients with severe disease, rather than the chronological age.

13 Jul 2020

New substance library established to accelerate the systematic development of drugs

In order to accelerate the systematic development of drugs, the MX team at the Helmholtz-Zentrum Berlin (HZB) and the Drug Design Group at the University of Marburg have established a new substance library.

13 Jul 2020

Altimmune announces positive preclinical results of intranasal COVID-19 vaccine candidate

Altimmune, Inc., a clinical-stage biopharmaceutical company, has announced positive results from the preclinical studies conducted in mice at the University of Alabama at Birmingham of its intranasal COVID-19 vaccine candidate, AdCOVID.

13 Jul 2020

COVID-19 – researchers sum up the “Tsunami” of information

The severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) infection leading to COVID-19 is a raging pandemic across the world at present. It has infected 13 million and killed 571,000 individuals around the world as of today. The infection was first reported in Wuhan, Hubei Province of China in late December 2019.

13 Jul 2020

Scientists discover common molecular feature found in SARS-CoV-2 neutralizing antibodies

A team led by scientists at Scripps Research has discovered a common molecular feature found in many of the human antibodies that neutralize SARS-CoV-2, the coronavirus that causes COVID-19.

13 Jul 2020

Study identifies three novel broad-spectrum SARS-CoV-2 cell entry inhibitors

Researchers from the National Institutes of Health (NIH) and Cornell University in the U.S. just described several new inhibitors of human coronavirus spike proteins by screening a library of approved drugs with SARS-S and MERS-S pseudotyped particle entry assays. Their exciting findings are currently available on the bioRxiv preprint server.

13 Jul 2020

New method can enhance the effectiveness of bacteria used in biotechnological applications

Scientists have developed a new computational technique that can be used to enhance the effectiveness of bacteria used in biotechnological applications.

13 Jul 2020

Serology distinguishes children with MIS-C associated with COVID-19

Researchers in the United States say that measuring antibody titers against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may help to distinguish between multisystem inflammatory syndrome in children (MIS-C) and other clinically similar syndromes.

13 Jul 2020

New chemical could potentially lead to a cure for neglected tropical diseases

Scientists say they are a step closer to developing a drug to kill the trypanosome parasite that causes human African trypanosomiasis, otherwise known as sleeping sickness, paving the way for a potential cure.

13 Jul 2020

Long-studied protein can be used as biomarker for traumatic brain injury

Scientists at the Walter Reed Army Institute for Research have recently demonstrated that cathepsin B, a well-studied protein important to brain development and function, can be used as biomarker, or indicator of severity, for traumatic brain injury.

13 Jul 2020

New radiotracer can directly measure synaptic changes following stroke

A new radiotracer, 18F-SynVesT-2, can directly assess synaptic density changes in the brain, providing an objective and quantitative measure of disease progression after stroke.

13 Jul 2020

Novel drug could enable the immune system to attack ovarian cancer

A drug known as SP-2577 could help enable the body's own immune system to attack ovarian cancer, according to a study led by the Translational Genomics Research Institute, an affiliate of City of Hope.

13 Jul 2020

Breakthrough discovery could lead to ‘kinder’ treatments for childhood bone cancer

Researchers at the University of East Anglia and University of Manchester have made an important breakthrough that could lead to ‘kinder’ treatments for children with bone cancer, and save lives.

13 Jul 2020

Researchers develop COVID-19 mortality risk calculator

A new study published in July 2020 on the preprint server medRxiv describes the use of machine learning to provide a better understanding of the risk factors in large and mixed groups. The use of algorithms can help objectively evaluate these factors and perhaps capture interactions that could be missed in a purely observational study.

13 Jul 2020

Dysfunctional T cells present at high levels in severe COVID-19

Now, a new study by researchers at Saarland University, Germany, and published on the preprint server medRxiv in July 2020 shows that there are higher levels of anti-SARS-CoV-2 T cells, which show significant alterations in the phenotype and function.

12 Jul 2020

No unique viral sequences found in pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2

In contrast to previous hypotheses, researchers from the University College London and Great Ormond Street Hospital for Children NHS Foundation Trust found no evidence of unique viral sequences from patients with pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS). Their study is published on the medRxiv* preprint server.

12 Jul 2020

New mutation in common subtype of influenza virus helps evade immune response

Strains of a common subtype of influenza virus, H3N2, have almost universally acquired a mutation that effectively blocks antibodies from binding to a key viral protein, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

12 Jul 2020

Study documents intrauterine transmission of SARS-CoV-2 infection during pregnancy

A baby girl in Texas - born prematurely to a mother with COVID-19 - is the strongest evidence to date that intrauterine (in the womb) transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can occur, reports The Pediatric Infectious Disease Journal, the official journal of The European Society for Paediatric Infectious Diseases.

12 Jul 2020

Fat cell hormone enhances therapeutic potential of MSC therapy

Mesenchymal stem cells (MSCs) have the potential to differentiate into a range of different cell types, including bone, fat, and muscle cells.

12 Jul 2020

Protein News and Research

Further Reading

Researchers uncover new mechanism for designing antiviral drugs for dengue virus

People with accelerated biological age at increased risk of COVID-19 symptom severity and mortality

New substance library established to accelerate the systematic development of drugs

Altimmune announces positive preclinical results of intranasal COVID-19 vaccine candidate

COVID-19 – researchers sum up the “Tsunami” of information

Scientists discover common molecular feature found in SARS-CoV-2 neutralizing antibodies

Study identifies three novel broad-spectrum SARS-CoV-2 cell entry inhibitors

New method can enhance the effectiveness of bacteria used in biotechnological applications

Serology distinguishes children with MIS-C associated with COVID-19

New chemical could potentially lead to a cure for neglected tropical diseases

Long-studied protein can be used as biomarker for traumatic brain injury

New radiotracer can directly measure synaptic changes following stroke

Novel drug could enable the immune system to attack ovarian cancer

Breakthrough discovery could lead to ‘kinder’ treatments for childhood bone cancer

Researchers develop COVID-19 mortality risk calculator

Dysfunctional T cells present at high levels in severe COVID-19

No unique viral sequences found in pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2

New mutation in common subtype of influenza virus helps evade immune response

Study documents intrauterine transmission of SARS-CoV-2 infection during pregnancy

Fat cell hormone enhances therapeutic potential of MSC therapy

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