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First U.S. patient treated with innovative gene therapy at Bascom Palmer Eye Institute

A Puerto Rican patient with X-linked retinitis pigmentosa (XLRP) is hoping to save his vision after an innovative gene therapy procedure at Bascom Palmer Eye Institute at the University of Miami Miller School of Medicine.

19 Sep 2018

Addition of CTLA4 targeted therapy to PD-1 targeted therapy may benefit patients with ovarian cancer

An analysis of the NRG Oncology clinical trial NRG-GY003 suggests that adding ipilimumab, a monoclonal antibody that targets the protein receptor CTLA-4, to a regimen with the checkpoint inhibitor nivolumab could improve the proportion with tumor response and progression-free survival hazard rates for women with recurrent epithelial ovarian cancer.

19 Sep 2018

More doctor visits can lower risk of suicide attempts in fibromyalgia patients

Fibromyalgia patients who regularly visit their physicians are much less likely to attempt suicide than those who do not, according to a new Vanderbilt University Medical Center study published in Arthritis Care & Research.

19 Sep 2018

Researchers use larval zebrafish model to reveal role of locus coeruleus in anesthesia

The application of general anesthesia in clinical therapy has been an indispensable part of modern medicine for more than a century. However, due to the complexity of the brain and the extensive actions of general anesthetic drugs, neural mechanisms underlying general anesthesia have remained a mystery.

19 Sep 2018

Home-based video game exercises can reduce chronic low back pain in older people, study finds

New research from University of Sydney has found home-based video-game exercises can reduce chronic low back pain in older people by 27 percent, which is comparable to benefits gained under programs supervised by a physiotherapist.

19 Sep 2018

Ipsen receives approval from Health Canada for CABOMETYX tablets for treating renal cell carcinoma

Exelixis, Inc. today announced that its partner Ipsen Biopharmaceuticals Canada Inc. received approval from Health Canada of CABOMETYX® tablets for the treatment of adults with advanced renal cell carcinoma who have received prior vascular endothelial growth factor targeted therapy.

19 Sep 2018

AmpliPhi receives positive feedback from FDA for its AB-PA01 product targeting P.aeruginosa infections

AmpliPhi Biosciences Corporation, a clinical-stage biotechnology company focused on precisely targeted bacteriophage therapeutics for antibiotic-resistant infections, today announced that the company has received positive feedback, via written response, from the U.S. Food and Drug Administration regarding its development plans for AB-PA01, without the need for a Type B Pre-IND meeting.

19 Sep 2018

Surprising research showing peptide adaptability may pave way to develop immunotherapies

The body's immune system is a valiant weapon against disease, and harnessing its power through a technique called immunotherapy is at the forefront of current research to treat cancer and other diseases.

19 Sep 2018

Researchers use CRISPR screen to reveal new targets in squamous cell carcinomas

A little p63 goes a long way in embryonic development - and flaws in p63 can result in birth defects like cleft palette, fused fingers or even missing limbs.

18 Sep 2018

Use of transcranial electrical stimulation to bolster creativity has far-reaching implications

What is creativity, and can it be enhanced -- safely -- in a person who needs a boost of imagination? Georgetown experts debate the growing use of electrical devices that stimulate brain tissue, and conclude there is potential value in the technique. However, use of these machines also raises neuro-ethical, legal, and social issues that must now be addressed.

18 Sep 2018

Microbiota in the intestines and cell stress cause colon cancer

"With our study we originally wanted to study the role of bacteria in the intestines in the development of intestinal inflammation," explains Professor Dirk Haller from the Department of Nutrition and Immunology at the Weihenstephan Science Centre of the TUM.

18 Sep 2018

Human brains may be wired to prefer lying on the couch, suggests research

If getting to the gym seems like a struggle, a University of British Columbia researcher wants you to know this: the struggle is real, and it's happening inside your brain.

18 Sep 2018

Logos Biosystems releases new electrophoretic tissue clearing system with twice the features in half the space

Logos Biosystems has released the latest system for electrophoretic tissue clearing, the X-CLARITY™ Tissue Clearing System II. The new system has been upgraded with new features that make it streamlined, easier to use and more intuitive.

From Logos Biosystems 18 Sep 2018

Purifying Proteins from Mammalian Cell Culture

In many cases mammalian cells are the only option to produce recombinant proteins with correct post-translational modifications, e.g. glycosylation, which are required for proper function of the therapeutic protein.

From Sartorius 18 Sep 2018

Outcome of ACL reconstruction related to the way you move post-surgery

A third of people who undergo ACL reconstruction surgery will have osteoarthritis in their injured knee within 10 years. Within two decades, nearly 50 percent will -- terrible odds for getting a debilitating condition with no known cure.

18 Sep 2018

Targeted Lung Denervation procedure significantly reduces COPD problems

First results from a clinical trial of a procedure to open obstructed airways in patients with chronic obstructive pulmonary disease have shown that it significantly reduces problems associated with the disease and is safe.

18 Sep 2018

More women veterans with chronic pain use CIH therapies than men

A recent major shift in practice by the Veterans Health Administration now means that complementary and integrative health therapies such as meditation, yoga and acupuncture are increasingly being offered to VA patients as non-drug approaches for pain management and related conditions, says Elizabeth Evans, an epidemiology researcher in the School of Public Health and Health Sciences at the University of Massachusetts Amherst.

18 Sep 2018

Sleep apnea, congenital heart disease in hospitalized infants strongly associated with death

Infants often aren't screened for sleep apnea, but a new study suggests the disorder may be tied to an increased risk of death in infants with congenital heart disease.

17 Sep 2018

People battling substance use disorders may benefit from meth-relapse prevention compound

New research raises the possibility that a wider group of people battling substance use disorders may benefit from a Scripps Research-developed relapse-prevention compound than previously thought.

17 Sep 2018

Concussion symptoms last for longer time in kids than adults

Concussion symptoms for children under 13 years old typically last three times longer than they do for older teens and adults, but keeping them out of the classroom during recovery is not necessarily the preferred treatment, according to a comprehensive research review in The Journal of the American Osteopathic Association.

17 Sep 2018

Therapy News and Research

First U.S. patient treated with innovative gene therapy at Bascom Palmer Eye Institute

Addition of CTLA4 targeted therapy to PD-1 targeted therapy may benefit patients with ovarian cancer

More doctor visits can lower risk of suicide attempts in fibromyalgia patients

Researchers use larval zebrafish model to reveal role of locus coeruleus in anesthesia

Home-based video game exercises can reduce chronic low back pain in older people, study finds

Ipsen receives approval from Health Canada for CABOMETYX tablets for treating renal cell carcinoma

AmpliPhi receives positive feedback from FDA for its AB-PA01 product targeting P.aeruginosa infections

Surprising research showing peptide adaptability may pave way to develop immunotherapies

Researchers use CRISPR screen to reveal new targets in squamous cell carcinomas

Use of transcranial electrical stimulation to bolster creativity has far-reaching implications

Microbiota in the intestines and cell stress cause colon cancer

Human brains may be wired to prefer lying on the couch, suggests research

Logos Biosystems releases new electrophoretic tissue clearing system with twice the features in half the space

Purifying Proteins from Mammalian Cell Culture

Outcome of ACL reconstruction related to the way you move post-surgery

Targeted Lung Denervation procedure significantly reduces COPD problems

More women veterans with chronic pain use CIH therapies than men

Sleep apnea, congenital heart disease in hospitalized infants strongly associated with death

People battling substance use disorders may benefit from meth-relapse prevention compound

Concussion symptoms last for longer time in kids than adults

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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