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Updated recommendations for HIV prevention and treatment in adults

The International Antiviral Society-USA Panel has released updated recommendations for the treatment and prevention of HIV infection in adults, published in the Journal of the American Medical Association. Michael Saag, M.D., director of the University of Alabama at Birmingham's Center for AIDS Research, served as the article's lead author.

24 Jul 2018

New applications for high-throughput flow cytometry in drug discovery

A new special issue of SLAS Discovery reflects examples of the recent groundswell of creative new applications for high-throughput flow cytometry in drug discovery.

24 Jul 2018

Researchers report first randomized trial results of 'kick and kill' approach to treat HIV

Researchers have reported the results of the first randomized clinical trial to test a novel strategy involving waking up and then killing the 'sleeping' HIV that is hiding in the body using an experimental approach known as 'kick and kill'.

24 Jul 2018

'Hijacked' cell response to stress reveals potential therapeutic targets for leukemia

A signaling pathway that helps promote normal cell growth worsens a form of leukemia by taking control of another pathway better known for protecting cells from biological stress, a new study shows.

24 Jul 2018

Mutated gene linked to 3-year-old girl's severe neurological symptoms

A young girl with severe neurological symptoms finally has a diagnosis, following the discovery by the Translational Genomics Research Institute of a genetic mutation that likely caused the girl to experience a cascade of symptoms.

24 Jul 2018

Promising approach to stem cell therapy for treating Parkinson's disease

A major factor underlying Parkinson's Disease pathology is the loss of dopamine neurons in the substantia nigra, and thus current therapies often aim to restore dopamine signaling. However, these treatments are not curative.

24 Jul 2018

Alzheimer’s disease greater in females, researchers speculate

This week, at the Alzheimer's Association International Conference in Chicago, a group of researchers presented reserch findings on the gender differences in Alzheimer’s causation. They speculated that women might be getting Alzheimer’s and dementia more commonly than men and the reason behind this has not been clearly understood. Estrogen or the female hormone could be the key, the researchers state.

23 Jul 2018

Researchers shed light on risks presented by residual disease for younger breast cancer patients

A new study from the Stanford Cancer Institute finds that young women who are treated with chemotherapy for breast cancer but have residual tumor in either the breast or lymph nodes have higher chances of recurrence compared to those with no evidence of any residual invasive tumor (pathologic complete response).

23 Jul 2018

Scientists find key link between viruses and inflammatory bowel diseases

A study led by a researcher at the University of Colorado Anschutz Medical Campus reveals a key connection between viruses and inflammatory bowel diseases like ulcerative colitis and Crohn's disease.

23 Jul 2018

Virtual reality may improve empathy and understanding for older adults with dementia

Virtual reality technology gives high school students greater insight into what it's like to be Alfred -- a 74-year-old African American man with suspected mild cognitive impairment, plus age-related vision and hearing loss, or Beatriz, a middle-aged Latina, as she progresses through the continuum of Alzheimer's disease.

23 Jul 2018

Long-term use of cannabis or cannabis-based drugs can impair memory, shows study

Long-term use of either cannabis or cannabis-based drugs impairs memory say researchers. The study has implications for both recreational users and people who use the drug to combat epilepsy, multiple sclerosis and chronic pain.

23 Jul 2018

Psychologists devise new intervention to address anxiety symptoms in bipolar disorder patients

Psychologists at Lancaster University have devised a novel psychological intervention to address Anxiety in Bipolar Disorder.

23 Jul 2018

Pfizer announces FDA approval of biosimilar to Neupogen

Pfizer Inc. today announced that the United States Food and Drug Administration has approved NIVESTYM (filgrastim-aafi), a biosimilar to Neupogen (filgrastim), for all eligible indications of the reference product.

23 Jul 2018

Australian-led global guidelines for diagnosis and treatment of women with PCOS

Australian led global guidelines for the diagnosis and treatment of the primary cause of infertility in women will be published simultaneously in three international journals, supported by a suite of health professional and patient resources to improve health outcomes for women with PCOS.

23 Jul 2018

Researchers study efficacy and safety of new treatment for OUD

Better delivery of medications to treat opioid use disorder is key to addressing the opioid crisis and helping the 2.6 million Americans affected by the disease.

20 Jul 2018

UC San Diego researchers awarded two grants for investigating stem cell-based therapies

The governing board of the California Institute for Regenerative Medicine unanimously approved this week two grants worth more than $2.2 million to University of California San Diego School of Medicine researchers investigating stem cell-based therapies for a rare genetic disorder that affects the heart and a chronic, progressive affliction of the lungs.

20 Jul 2018

FDA approves first drug for treatment of adult AML patients with specific genetic mutation

The U.S. Food and Drug Administration today approved Tibsovo (ivosidenib) tablets for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) who have a specific genetic mutation.

20 Jul 2018

Karius Test accurately detects invasive fungal infections, shows study

Karius, a life sciences company transforming infectious disease diagnostics with genomics and data through the innovative use of next-generation sequencing to analyze microbial cell-free DNA, announced today the positive results of a clinical study using blood samples from patients with confirmed invasive fungal infections.

20 Jul 2018

Researchers present evidence of phage cooperation when attacking CRISPR-containing bacteria

CRISPR, or clustered regularly interspaced short palindromic repeats, are an essential part of bacterial immunity designed to defend against foreign DNA. In bacteria, CRISPR acts just like it does in human cells as a pair of scissors, in their case with the goal of cutting strands of infecting DNA.

20 Jul 2018

Drug in clinical trials for Parkinson's disease offers hope for treating heart failure

A drug currently in clinical trials for treating symptoms of Parkinson's disease may someday have value for treating heart failure, according to results of early animal studies by Johns Hopkins Medicine researchers.

20 Jul 2018

Therapy News and Research

Updated recommendations for HIV prevention and treatment in adults

New applications for high-throughput flow cytometry in drug discovery

Researchers report first randomized trial results of 'kick and kill' approach to treat HIV

'Hijacked' cell response to stress reveals potential therapeutic targets for leukemia

Mutated gene linked to 3-year-old girl's severe neurological symptoms

Promising approach to stem cell therapy for treating Parkinson's disease

Alzheimer’s disease greater in females, researchers speculate

Researchers shed light on risks presented by residual disease for younger breast cancer patients

Scientists find key link between viruses and inflammatory bowel diseases

Virtual reality may improve empathy and understanding for older adults with dementia

Long-term use of cannabis or cannabis-based drugs can impair memory, shows study

Psychologists devise new intervention to address anxiety symptoms in bipolar disorder patients

Pfizer announces FDA approval of biosimilar to Neupogen

Australian-led global guidelines for diagnosis and treatment of women with PCOS

Researchers study efficacy and safety of new treatment for OUD

UC San Diego researchers awarded two grants for investigating stem cell-based therapies

FDA approves first drug for treatment of adult AML patients with specific genetic mutation

Karius Test accurately detects invasive fungal infections, shows study

Researchers present evidence of phage cooperation when attacking CRISPR-containing bacteria

Drug in clinical trials for Parkinson's disease offers hope for treating heart failure

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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