Aspirin News and Research

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Aspirin also known as acetylsalicylic acid is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. Aspirin also has an antiplatelet, or "anti-clotting", effect and is used in long-term, low doses to prevent heart attacks, strokes and blood clot formation in people at high risk for developing blood clots. It has also been established that low doses of aspirin may be given immediately after a heart attack to reduce the risk of another heart attack or of the death of cardiac tissue.

Too little or too much testosterone may matter for heart rhythm

A review of clinical trials, observational studies, genetic analyses, and mechanistic research suggests that atrial fibrillation risk may follow a U-shaped relationship with testosterone, increasing at both low and high levels. Evidence on testosterone replacement therapy remains mixed, with researchers calling for prospective studies to determine whether mid-physiological testosterone targets and treatment formulation influence AF risk.

2 Sep 2026

Anticoagulation lowers subclinical leaflet thrombosis after TAVI procedure

After transcatheter aortic valve implantation (TAVI), anticoagulation reduced imaging signs of clot formation on the new valve compared with antiplatelet therapy, without compromising safety. This was the main finding of the ACASA-TAVI trial presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in JAMA.

31 Aug 2026

SWITCH SWEDEHEART trial shows prasugrel matches ticagrelor with less bleeding

Prasugrel reduced major cardiovascular events to the same extent as ticagrelor but with lower major bleeding after coronary stenting in patients with acute coronary syndromes, according to results from the SWITCH SWEDEHEART trial presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in the New England Journal of Medicine.

29 Aug 2026

Trial shows antiplatelet therapy needs personalization after stent implantation

Antiplatelet monotherapy reduced bleeding but dual therapy provided greater cardiovascular event protection in patients at high ischemic risk who had undergone stent implantation 12 months earlier.

29 Aug 2026

Trial findings do not support prasugrel monotherapy at the time of primary PCI for STEMI patients

Monotherapy using prasugrel failed to show noninferiority compared with potent antiplatelet therapy plus aspirin at the time of primary percutaneous coronary intervention for ST-segment elevation myocardial infarction.

29 Aug 2026

Potent antiplatelet therapy increases bleeding risk after heart attack in AF patients

Potent antiplatelet therapy increased bleeding without signs of benefit regarding cardiovascular events in patients with atrial fibrillation after a heart attack.

29 Aug 2026

New findings do not support the use of edoxaban in AF patients after intracranial hemorrhage

Edoxaban did not reduce stroke or systemic embolism but increased major bleeding in high-risk patients with atrial fibrillation who had had an intracranial hemorrhage, according to results presented in a Hot Line session today at ESC Congress 2026.

29 Aug 2026

Würzburg researchers discover alternative approach to preventing thrombosis

Glycoprotein VI, or GPVI for short, is a surface receptor found exclusively on platelets and their precursor cells, megakaryocytes in the bone marrow.

14 Aug 2026

Omega-3 and ASA combination shows promise for severe periodontitis

A combination of omega-3 and low-dose acetylsalicylic acid (ASA) produced results comparable to antibiotics in treating severe periodontitis.

6 Aug 2026

Spermidine boosts key cellular processes linked to aging in early research

This review finds that spermidine supports autophagy, mitochondrial function, and healthspan in experimental models, while observational studies link higher dietary intake to lower mortality. However, human trials have produced limited and mixed results, leaving its clinical role in healthy aging unresolved.

23 Jul 2026

Researchers identify immune cell receptor that drives organ aging process

We may age at different rates, but none of us escapes aging. A study in mice and in human cells by Stanford Medicine researchers pins much of the blame on a particular type of immune cell's increased inability, with advancing age, to gobble up another immune cell type.

16 Jul 2026

Lung tumors hack the nervous system to cause severe cachexia

Cachexia is a condition in which patients affected by cancer or other chronic diseases become sick and lose weight.

9 Jul 2026

Updated ABCs framework gives clinicians a clearer path to prevent heart disease

A 2026 State-of-the-Art review updates the ABCs of cardiovascular disease prevention to help clinicians apply contemporary risk assessment, lifestyle, pharmacologic, and cardiometabolic strategies in routine care. The framework emphasizes PREVENT™ risk equations, Life’s Essential 8, CKM syndrome, obesity care, lipid lowering, blood pressure control, healthy aging, heart failure prevention, and atrial fibrillation management.

7 Jul 2026

Lung tumors hijack nervous system to drive cancer-related cachexia

According to the Cleveland Clinic, a quarter of cancer deaths can be attributed to one source: cachexia. Cachexia is a syndrome that accompanies underlying chronic illness and causes unwanted muscle and fat loss, reducing quality of life and sometimes even limiting treatment options.

2 Jul 2026

Hyperemesis gravidarum increases risks for pregnancy and birth complications

Pregnant women with a severe form of nausea face increased risks for several pregnancy and birth complications, according to a new Stanford Medicine study of 2.5 million California births.

22 Jun 2026

New protein discovery could lead to safer antithrombotic therapies

Antiplatelet drugs are one of the main tools used to prevent thrombus formation in people who have had a heart attack or stroke or who have cardiovascular diseases with a high thrombotic risk.

17 Jun 2026

BU professor to examine the role of postpartum hypertension on recurrent HDP risk

Samantha Parker Kelleher, along with researchers at BU School of Public Health and Boston Medical Center, will examine the role of high blood pressure during the postpartum period on the risk of developing recurrent hypertensive disorders of pregnancy, such as preeclampsia and gestational hypertension.

11 Jun 2026

Aspirin use may help unmask early asymptomatic bladder cancer

The presence of blood cells in urine is a sign of bladder cancer. Because aspirin blocks platelets from forming harmful blood clots, the medication can cause mild bleeding or worsen existing bleeding in the urinary tract.

3 Jun 2026

Pregnancy magnifies heart risk, but age alone does not explain why

A large U.S. cohort-crossover study found that pregnancy and the postpartum period were linked to about a seven-fold higher relative risk of major adverse cardiovascular events compared with patients’ nonpregnant baseline risk. This relative risk increase did not vary by maternal age, suggesting pregnancy broadly amplifies existing cardiovascular risk rather than making older age itself the driver of pregnancy-specific cardiovascular complications.

20 May 2026

Icing injuries may delay healing and prolong pain recovery

Icing a sprained ankle or sore muscle, long used to reduce pain and swelling, may in the longer run delay recovery and prolong pain, new research suggests.

13 May 2026