Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

FAU study uses Raman spectroscopy and AI to detect skin cancer

Skin cancer is the most common cancer in the United States and among the most common worldwide. Nearly 1.5 million new cases were diagnosed globally in 2024, including nearly 340,000 melanomas.

1 Oct 2026

Highlight Therapeutics presents positive Phase 2b topline results of intralesional BO‑112 in localized basal cell carcinoma as a late-breaker at EADV

Highlight Therapeutics, a clinical‑stage biotechnology company developing immune activators to transform the treatment of skin tumors, today announced positive results from the multicenter, single-arm Phase 2b SPOTLIGHT‑204 clinical trial evaluating BO‑112, a novel dsRNA-based intralesional treatment for patients with resectable primary low‑ and high‑risk basal cell carcinoma (BCC).

1 Oct 2026

Esophageal cancer leaves a distinct metabolic signature in the gut

The study uncovers gut microbial and metabolic signatures in esophageal cancer, emphasizing lipid dysregulation and its potential role in disease progression.

1 Oct 2026

Novel surgical technique restores clitoral sensation using buccal mucosa graft

For women who lose part of their clitoris because of vulvar cancer, a clitoral reconstruction procedure has now been developed for the first time. This comes forty years after the first penile reconstruction surgery. Results in the initial group of patients are encouraging.

1 Oct 2026

Weekly cisplatin fails to reduce acute toxicity in advanced head and neck cancer

Physicians typically use either a higher dose of cisplatin given every three weeks or a lower dose given weekly in combination with radiation to treat locally advanced head and neck cancer.

29 Sep 2026

Review highlights how altered metabolism drives kidney cancer growth

Clear cell renal cell carcinoma (ccRCC), the most common subtype of kidney cancer, is increasingly understood as a malignancy shaped by profound changes in cellular metabolism.

24 Sep 2026

Blood test detects more cancers when added to standard screening

A single blood draw that screens for more than 50 cancers substantially increased cancer detection when added to standard screening, identifying cancers that otherwise might have gone undetected until later stages, according to a new study from the Oregon Health & Science University Knight Cancer Institute.

22 Sep 2026

New scanning method detects basal cell carcinoma early using AI

Researchers at FAU combine optical diagnosis method with AI-assisted image recognition.

22 Sep 2026

New spin-out launches technology to revolutionize hormone disorder diagnosis

The University of Birmingham and Imperial College London have announced the launch of Intelligent Mass Spec Solutions Ltd (IMS Solutions), a new spin-out that is set to revolutionize diagnosis of conditions featuring disordered steroid hormone metabolism.

22 Sep 2026

Study defines early-onset cirrhosis caused by fatty liver disease

Researchers at University of California San Diego School of Medicine have published the first study to define early-onset cirrhosis caused by metabolic dysfunction-associated steatotic liver disease (MASLD), a condition known as fatty liver disease.

16 Sep 2026

Study provides a clearer picture of the extent of overdiagnosis in breast cancer screening

When women take part in breast cancer screening, they are informed that screening may detect cancers that would never have caused symptoms or problems during their lifetime. This is known as overdiagnosis.

15 Sep 2026

Genomic profiling uncovers distinct TP53 and PI3K pathways across tumor budding grades

A newly proposed International Association for the Study of Lung Cancer (IASLC) tumor budding-based grading system successfully identified patients with resected lung squamous cell carcinoma (SqCC) at higher risk of poor outcomes and showed potential to help guide selection for adjuvant chemotherapy, according to research presented at the IASLC 2026 World Conference on Lung Cancer on Lung Cancer. (WCLC).

15 Sep 2026

Like your tea or coffee very hot? A study of nearly 1 million adults found a striking cancer link

In pooled prospective data from 977,282 UK adults, preferring tea or coffee “very hot” was associated with more than threefold higher risk of esophageal squamous cell carcinoma compared with preferring drinks “warm,” while drink temperature showed no material association with adenocarcinoma risk. Consuming six or more hot drinks daily was independently associated with higher squamous cell carcinoma risk, and modeling estimated that about 440 UK cases each year could be prevented by switching from “very hot” to “hot” drinks if the association is causal.

14 Sep 2026

New treatment approach preserves organs, improves survival in head and neck cancer patients

Patients with locally advanced head and neck squamous cell carcinoma (HNSCC) whose tumors responded to neoadjuvant immunochemotherapy (ICT) and who underwent less extensive surgery had high disease-free survival and organ preservation rates.

10 Sep 2026

New integrated framework advances precision surgery for liver cancer

Hepatocellular carcinoma is the sixth most common malignancy and the third leading cause of cancer-related death globally.

9 Sep 2026

Alcohol-related liver cancer deaths were falling. Then the trend reversed during the COVID-19 pandemic

A global analysis of GBD 2023 data found that alcohol-attributable liver cancer mortality increased modestly from 1990 to 2023, while mortality from alcohol-attributable cirrhosis, alcoholic cardiomyopathy, and alcohol use disorders declined. Liver cancer mortality shifted from a pre-pandemic decline to an increase during 2020–2023, particularly among women, although the researchers cautioned that the ecological analysis cannot establish that pandemic-related changes caused the reversal.

1 Sep 2026

Study identifies KRAS G12C as a precision-medicine target in genitourinary cancers

A new research paper was published in Volume 17 of Oncotarget on August 19, 2026, titled "Incidence of KRAS G12C mutations in genitourinary malignancies; emerging target in precision medicine."

28 Aug 2026

Newly developed radiotheranostic pair identifies and treats renal tumors

A newly developed radiotheranostic pair, 68Ga/177Lu-NYM096, can identify tumors and effectively deliver targeted radiotherapy to patients with metastatic clear cell renal cell carcinoma (ccRCC).

28 Aug 2026

New review examines oral cancer drug delivery barriers and strategies

Delivering drugs directly to oral tumor sites remains challenging. A recent review involving researchers from Hasanuddin University examines barriers to local drug delivery and analyses strategies for targeting oral cancer lesions.

26 Aug 2026

NIH grants support research on whether PFAS exposure increases risk of liver and endometrial cancers

Researchers at the Keck School of Medicine of USC and USC Norris Comprehensive Cancer Center have received two grants from the National Institutes of Health (NIH) totaling $7.5 million to study whether exposure to per- and polyfluoroalkyl substances (PFAS), the synthetic compounds known as "forever chemicals," increases the risk of liver cancer and endometrial cancer.

25 Aug 2026

Carcinoma News and Research

Further Reading

FAU study uses Raman spectroscopy and AI to detect skin cancer

Highlight Therapeutics presents positive Phase 2b topline results of intralesional BO‑112 in localized basal cell carcinoma as a late-breaker at EADV

Esophageal cancer leaves a distinct metabolic signature in the gut

Novel surgical technique restores clitoral sensation using buccal mucosa graft

Weekly cisplatin fails to reduce acute toxicity in advanced head and neck cancer

Review highlights how altered metabolism drives kidney cancer growth

Blood test detects more cancers when added to standard screening

New scanning method detects basal cell carcinoma early using AI

New spin-out launches technology to revolutionize hormone disorder diagnosis

Study defines early-onset cirrhosis caused by fatty liver disease

Study provides a clearer picture of the extent of overdiagnosis in breast cancer screening

Genomic profiling uncovers distinct TP53 and PI3K pathways across tumor budding grades

Like your tea or coffee very hot? A study of nearly 1 million adults found a striking cancer link

New treatment approach preserves organs, improves survival in head and neck cancer patients

New integrated framework advances precision surgery for liver cancer

Alcohol-related liver cancer deaths were falling. Then the trend reversed during the COVID-19 pandemic

Study identifies KRAS G12C as a precision-medicine target in genitourinary cancers

Newly developed radiotheranostic pair identifies and treats renal tumors

New review examines oral cancer drug delivery barriers and strategies

NIH grants support research on whether PFAS exposure increases risk of liver and endometrial cancers

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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