Cell Metabolism News and Research

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Key innate immune protein regulates cholesterol and influences cancer treatment resistance

Scientists at the University of North Carolina Lineberger Comprehensive Cancer Center have discovered an unexpected role for a key innate immune protein, revealing how it helps regulate cholesterol levels inside cells and influences tumor growth and treatment response.

3 Nov 2026

New international initiative explores how energy shapes brain function

Professor Tim Vogels from the Institute of Science and Technology Austria (ISTA) will receive $3 million as part of an ambitious new $80 million international research initiative exploring how energy shapes brain function.

2 Nov 2026

BioUK Awards 2026 celebrate outstanding achievement and breakthrough innovations from across the life sciences

BioUK, the not-for-profit membership organization focused on catalyzing success in UK life sciences, today announced the winners of the 18th annual BioUK Awards following a ceremony hosted at the Royal Lancaster Hotel, London.

From BioUK 23 Oct 2026

Altered fatty acid metabolism drives glioblastoma growth and treatment resistance

Glioma is the most common primary malignant brain tumor in adults, and glioblastoma (GBM), particularly IDH (Isocitrate dehydrogenase)-wildtype disease, has the poorest prognosis.

21 Oct 2026

UCLA scientist develops new way to map cellular metabolism

Nutrition advice is everywhere. Eat more protein. Cut back on sugar. Get more fiber. But beneath all that advice is a surprisingly basic gap in our understanding: Scientists still have a limited view of what happens when specific nutrients reach individual cells inside the body.

6 Oct 2026

Obesity disrupts ILC2 metabolism through increased fatty acid uptake

A group of innate immune cells, known as group 2 lymphoid cells (ILC2), are essential for maintaining a stable metabolism in adipose tissue. Obesity significantly impairs the number and function of ILC2 cells, leading to the progression of metabolism-related inflammation.

23 Sep 2026

Rituximab alters T-cell metabolism in patients with nephrotic syndrome

Nephrotic syndrome is caused when the filtering system in the kidneys is damaged, allowing large amounts of protein to leak into the urine.

10 Sep 2026

AI-designed drug candidate reverses biological age in clinical study

Insilico Medicine ("Insilico"), a clinical-stage company focused on generative AI-driven drug discovery and development, today announced the publication of a new study conducted in collaboration with an international team of scientists from Harvard Medical School, Stanford University, The Broad Institute, RWTH Aachen University, Peking University and Westlake University.

7 Sep 2026

MXene-based hydrogel offers dual-action treatment for periodontitis

Periodontitis is a highly prevalent chronic inflammatory disease worldwide. It leads to periodontal tissue destruction, alveolar bone resorption, and ultimately tooth loosening and loss, severely impacting patients' oral function and quality of life.

4 Sep 2026

New optical imaging reveals metabolic activity of individual immune cells

A routine blood sample contains a diverse collection of immune cells that can reveal important clues about health and disease.

2 Sep 2026

New nondestructive imaging technique tracks immune cell health

When a patient is facing certain cancers or an immune condition, clinicians turn to their white blood cells for clues about the progression of both diseases and their treatments.

1 Sep 2026

UNC researcher wins major grant to study the role of endoplasmic reticulum in T-cell metabolism

Jessica Thaxton, PhD, MsCR, associate professor in the Department of Cell Biology and Physiology at the UNC School of Medicine and co-leader of the Cancer Cell Biology Research Program at UNC Lineberger Comprehensive Cancer Center, has been awarded a prestigious $700,000 grant from the Mathers Foundation to support research into the role of the endoplasmic reticulum in T-cell metabolism and cancer development.

1 Sep 2026

The scale told a similar story across three diets. The liver told a different one

In a randomized controlled trial of people with metabolically unhealthy obesity, approximately 10% weight loss improved insulin sensitivity and several cardiometabolic measures across ketogenic, Mediterranean, and very-low-fat plant-forward diets. However, the very-low-carbohydrate ketogenic diet produced larger improvements in hepatic insulin sensitivity and greater reductions in liver fat and several glucose and insulin measures than the higher-carbohydrate diets.

31 Aug 2026

Study shows how cancer can act as a systemic disease

In their quest to understand how cancers take root, grow and spread, scientists have for the past half-century explored the genetic aberrations and microenvironmental peculiarities of tumors and their constituent cells.

28 Aug 2026

Ketogenic diet excels at reversing prediabetes and fatty liver

There is no shortage of popular diets to try, and they can generally produce weight loss if followed to the letter. But are all diet plans created equal in terms of reducing the cardiometabolic risks that come with obesity, such as Type 2 diabetes and liver disease?

27 Aug 2026

Ketogenic diet provides greatest health benefits for treating obesity

A diet that severely limits carbohydrates but is high in fat has the greatest health benefits for people with obesity compared to a Mediterranean diet or a low-fat diet, according to a clinical trial publishing August 27 in the Cell Press journal Cell Metabolism.

27 Aug 2026

Dexamethasone calms lung inflammation without weakening core immune responses

Researchers from Trinity College Dublin and St. James's Hospital have shown that dexamethasone, a commonly prescribed anti-inflammatory steroid, can reduce harmful inflammation triggered by Mycobacterium avium without weakening the ability of human immune cells to control the infection.

11 Aug 2026

Natural hormone activates brain-to-liver signaling pathway to suppress liver inflammation

Researchers at McMaster University have discovered that a naturally occurring hormone best known for suppressing appetite and promoting weight loss also helps protect the liver from inflammation through a previously unknown signalling pathway, opening new possibilities for treating advanced fatty liver disease.

10 Aug 2026

Thinning cancer cells' sugar coating could expose tumors to immune attack

Like spies evading detection through being masters of disguise, many cancer cells are adorned with a copious coat of sugar-derived molecules that throws the proverbial hounds of our immune systems off the scent.

7 Aug 2026

Study reports a counterintuitive new approach to treating mesothelioma

Mesothelioma is a rare but aggressive cancer, usually caused by exposure to asbestos. Inhaled asbestos fibers become lodged in the lungs, causing inflammation that can lead to tumor formation decades later. Worldwide, about 30,000 people are diagnosed with mesothelioma each year.

14 Jul 2026