Coronary Artery Bypass Surgery News and Research

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Coronary Artery Bypass is surgery in which a healthy blood vessel taken from another part of the body is used to make a new path for blood around a blocked artery leading to the heart. This restores the flow of oxygen and nutrients to the heart. Also called aortocoronary bypass and CAB.

Major cardiac societies develop and publish a universal definition of myocardial infarction

When a myocardial infarction, such as a heart attack, occurs, being able to classify its type can improve diagnosis and treatment.

28 Aug 2026

AI-based tool matches standard method for coronary blood flow assessment

A novel, minimally invasive computer software-based method that uses artificial intelligence to determine whether plaques in a coronary artery are restricting blood flow to the patient's heart performed similarly to the standard, more invasive wire-based procedure, according to a large international randomized trial presented at the American College of Cardiology's Annual Scientific Session (ACC.26).

29 Mar 2026

Angioplasty improves symptoms in chronic total coronary occlusion patients

In what is believed to be the first randomized placebo-controlled trial of its kind, patients with a chronic total blockage of a coronary artery who received a nonsurgical procedure to reopen the artery showed statistically significant reductions in chest pain and improvements in quality of life compared with patients who received a placebo procedure.

29 Mar 2026

Landmark trial shows drug-eluting balloon as effective option for in-stent restenosis

Results from the first randomized clinical trial in the United States to compare a sirolimus-eluting balloon (DEB) to control group consisting of drug-eluting stent (DES) and balloon angioplasty (BA) for the treatment of bare-metal and DES in-stent restenosis (ISR) deemed DEB to be noninferior to conventional therapies.

28 Oct 2025

Cleveland Clinic study shows lasting benefits of weight-loss surgery over GLP-1 medicines

A large Cleveland Clinic study has found that people with obesity and type 2 diabetes who undergo weight-loss surgery live longer and face fewer serious health problems compared with those treated with GLP-1 receptor agonist medicines alone.

16 Sep 2025

Evolocumab fails to reduce vein graft disease after coronary artery bypass surgery

After coronary artery bypass grafting (CABG), evolocumab did not reduce saphenous vein graft disease rates at 2 years compared with placebo, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in Lancet.

3 Sep 2025

Real-world study finds lower weight loss with GLP-1 drugs due to early discontinuation

A Cleveland Clinic study shows that semaglutide and tirzepatide – injectable GLP-1 drugs for obesity – produce smaller weight loss in a real-world setting because patients discontinue treatment or use lower maintenance dosages.

10 Jun 2025

Tolebrutinib shows promise for treating non-relapsing secondary progressive multiple sclerosis

A Cleveland Clinic-led clinical trial of tolebrutinib, an investigational oral Bruton's tyrosine kinase inhibitor, a group of drugs originally developed to treat lymphomas and related blood disorders, demonstrated a 31% delay in the onset of six-month confirmed disability progression (CDP) in patients with non-relapsing secondary progressive multiple sclerosis (SPMS).

8 Apr 2025

Bariatric surgery reduces liver complications in obese patients with cirrhosis

A Cleveland Clinic study shows that patients with obesity and fatty liver-related cirrhosis who had bariatric (weight-loss) surgery significantly lowered their future risk of developing serious liver complications compared with patients who received medical therapy alone.

27 Jan 2025

Virtual yoga program shows promise for chronic low back pain relief

Cleveland Clinic researchers found that a 12-week therapeutic virtual yoga program for chronic low back pain can be a feasible, safe and effective treatment option. The findings are published in JAMA Network Open.

1 Nov 2024

Black patients face higher risks following coronary artery bypass grafting

Despite advances in cardiovascular medicine, Black patients are 22% more likely than white patients to die in the hospital after coronary artery bypass grafting (CABG) surgery, according to a study of more than 1 million patients presented at the ANESTHESIOLOGY 2024 annual meeting.

21 Oct 2024

Cleveland Clinic integrates AI-powered platform to enhance digestive disease care

To expand access to care for patients, Cleveland Clinic has added Ayble Health, an AI-enabled digital care platform, to its multidisciplinary care model for the treatment of chronic digestive diseases.

20 Oct 2024

New method aims to improve lung transplant access for hard-to-match candidates

Researchers at Cleveland Clinic and Case Western Reserve University (CWRU) have developed a new method that could potentially help provide better access to lung transplant for transplant candidates who are hard to match because of their blood type or height.

15 Oct 2024

Bariatric surgery outperforms GLP-1 medications in protecting kidney function

A Cleveland Clinic study showed that in patients with type 2 diabetes, obesity, and chronic kidney disease, bariatric surgery was associated with a significant decrease in the progression of chronic kidney disease compared to those who received GLP-1 diabetes medications. The paper was published in Annals of Surgery.

20 Sep 2024

Real-world data reveals factors associated with long-term weight loss in obesity

A Cleveland Clinic study identified key factors that can impact the long-term weight loss of patients with obesity who were prescribed injectable semaglutide or liraglutide for the treatment of type 2 diabetes or obesity. The study was published in JAMA Network Open.

14 Sep 2024

Cleveland Clinic and FitNow launch comprehensive diet and health app

Cleveland Clinic and app developer FitNow, Inc.  have launched the Cleveland Clinic Diet app, which offers health and diet advice built upon evidence-based nutrition science and clinical success, paired with a comprehensive food and fitness tracker.

28 Jun 2024

Researchers win $2.78 million grant to harness AI for precision treatment in rectal cancer

With a new five-year, $2.78 million grant from the National Institutes of Health and National Cancer Institute, researchers at Case Western Reserve University(CWRU), Cleveland Clinic and University Hospitals (UH) will use artificial intelligence (AI) to better treat rectal cancer patients.

24 Jun 2024

Bariatric surgery lowers heart risks and death rates in obese patients with sleep apnea

A Cleveland Clinic study shows that bariatric surgery performed in patients with obesity and moderate to severe obstructive sleep apnea is associated with a significantly lower risk of death and major adverse cardiovascular events, compared with patients who did not have the surgery.

21 Jun 2024

Xylitol linked to higher risk of cardiovascular events, Cleveland Clinic study finds

Cleveland Clinic researchers found higher amounts of the sugar alcohol xylitol are associated with increased risk of cardiovascular events like heart attack and stroke.

7 Jun 2024

Higher amounts of sugar alcohol xylitol associated with increased risk of cardiovascular events