Cyclosporine News and Research

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Cyclosporine is a drug used to help reduce the risk of rejection of organ and bone marrow transplants by the body. It is also used in clinical trials to make cancer cells more sensitive to anticancer drugs.

Plant-based eye drops harness photosynthesis to heal dry eyes

What if your eyes could use light to heal themselves? Drawing inspiration from how plants harness sunlight, researchers at the National University of Singapore (NUS) are pioneering a revolutionary treatment for dry eye disease.

20 May 2026

Manuka honey eye drops outperform artificial tears for dry eye relief

A clinical study reveals Manuka honey eye drops significantly improve dry eye symptoms after cataract surgery, outperforming traditional treatments.

1 May 2026

Understanding immune drift in biologic therapy for inflammatory skin diseases

Immune-inflammatory skin diseases (e.g., psoriasis, atopic dermatitis) involve dysregulation of CD4+ T-cell subsets (Th1/Th2/Th17/Treg) and cytokine networks (IL-17/IL-23/IL-4).

28 Jul 2025

McMaster study identifies the most effective and safest treatments for chronic hives

A new international study led by researchers at McMaster University has identified the most effective and safest treatments for people suffering from chronic urticaria, more commonly known as chronic hives.

15 Jul 2025

Can natural supplements backfire? Review explains how and why

A new review uncovers how common natural supplements can both protect and endanger health, depending on dose, duration, and delivery—and points to next-gen technologies as the key to unlocking their full therapeutic power.

31 Mar 2025

Ursodeoxycholic acid shows promise in treating drug-induced liver injury

Drug-induced liver injury (DILI) is a significant concern in clinical practice, arising from medications, herbs, and dietary supplements.

28 Feb 2025

Grapefruit juice and its effects on prescription drugs

Grapefruit juice can interfere with how certain medications work by affecting drug metabolism and absorption, leading to either increased side effects or reduced effectiveness. The FDA requires warnings on some drugs due to these interactions, making it essential to check labels and consult healthcare providers.

28 Feb 2025

Emerging therapies transform autoimmune hepatitis treatment approaches

Autoimmune hepatitis (AIH) is a chronic, progressive liver disease caused by immune system dysregulation that targets the liver. If untreated, AIH can lead to severe complications, including cirrhosis and liver failure.

6 Nov 2024

Key triggers for food allergies in children after organ transplants

Study reviews transplant-acquired food allergies, focusing on pediatric patients, particularly liver transplant recipients. It explores immune system dysfunction, immunosuppressive agents, and gut microbiota changes as contributors to the rise of food allergies after organ transplants.

23 Sep 2024

Review highlights mitochondrial dysfunction in cholestatic liver injury

Bile acids are essential signaling molecules derived from cholesterol metabolism in the liver and are crucial for the digestion and absorption of fats.

16 Sep 2024

Revolutionary advances in psoriasis treatment: unveiling new therapeutic approaches

Psoriasis etiopathogenesis and treatment.

29 Nov 2023

New standard more effective at preventing graft-versus-host disease

Clinicians have a new standard for graft-versus-host disease (GVHD) prevention after allogeneic hematopoietic stem cell transplantation, according to results from a phase III study published June 22 in the New England Journal of Medicine.

22 Jun 2023

Does nirmatrelvir and ritonavir reduce the risk of hospitalization or death among outpatients with early COVID-19?

Researchers investigated the efficacy of ritonavir and nirmatrelvir combination treatment in reducing the risk of COVID-19 severity outcomes such as hospital admissions and deaths when administered during the initial period of SARS-CoV-2 infections.

16 Dec 2022

What is the role of cyclophilin-A in alleviating SARS-CoV-2 infections?

A new study aimed to analyze the molecular interactions between the hCypA protein and the SARS-CoV-2 variants to determine the impact of variants on the blocking and binding potential of the hCypA–S protein complex with the ACE2 receptor.

2 Nov 2022

UT Southwestern physicians outline the risks of pregnancy in women with rheumatic disease

Pregnant women with active rheumatic disease carry a higher risk of adverse outcomes than the general population including hypertension, preeclampsia, higher cesarean section rate, small for gestational aged infants, preterm delivery, and fetal loss. To

19 Jul 2022

Study finds traditional African drug inhibits growth of SARS-CoV-2 infection

Researchers evaluated the efficacy of PHELA, a traditional African drug, against SARS-CoV-2 in vitro.

21 Jun 2022

Efficacy and safety of mRNA-based SARS-CoV-2 vaccination in immuno-compromised subjects

A team of researchers assessed the immune response after administering a SARS-COV-2 vaccine in immuno-compromised subjects who are potentially at an increased risk to experience severe COVID-19 and inadequate response to SARS-CoV2 vaccination.

17 Jan 2022

Kidney transplant patients are more susceptible to harmless bacterium, finds study

It's a pervasive bacterium found in soil and water that rarely causes disease, but a new national review of nocardia infection in people who have had a kidney transplant shows that when it occurs it most commonly causes pneumonia and brain abscess, and reminds their physicians to stay on the lookout for it, investigators say

11 Oct 2021

Could a fungus-derived compound reduce hyperinflammation in severe COVID-19?

New research from scientists at the University of Pennsylvania, USA, demonstrates that cyclosporine A (CSA), a calcineurin inhibitor that modulates cytokine production, may have potential antiviral properties against coronaviruses.

18 Jun 2021

Scientists identify nine potential new COVID-19 treatments

A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has identified nine potential new COVID-19 treatments, including three that are already approved by the Food and Drug Administration (FDA) for treating other diseases.

2 Apr 2021