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Common overactive bladder drugs may not increase dementia risk

New research, published November 6th in JAMA Network Open, finds anticholinergic medications, commonly prescribe for overactive bladder (OAB), may not increase dementia risk after all compared to beta-3 agonists, the newer drug class that has been presumed to be safer for the brain.

6 Nov 2026

Light-powered reaction gives discarded drug compounds new potential

Throughout the drug development process, which can take a decade or more, tens of thousands of chemical compounds are produced that never go on to become medicines.

6 Nov 2026

Obesity drugs may help protect memory and cognitive abilities

Drugs used to treat obesity may also help protect the brain. In a review published in Science, researchers outline how a better understanding of these drugs' effects could lead to new treatments that protect memory and other important cognitive abilities.

6 Nov 2026

New microscopy technique reveals how drugs affect living cells

How do cells respond to drugs? A new microscopy technique could provide more precise answers to this question in the future.

5 Nov 2026

Review examines translational bottlenecks for plant-derived anti-inflammatory compounds

A review led by Professor Weidong Zhang at the School of Pharmacy, Naval Medical University, was published in Volume 2 of the journal Immunity & Inflammation on October 27, 2026. The article systematically examines the translational bottlenecks and potential solutions for plant-derived anti-inflammatory compounds.

5 Nov 2026

CIRM grant funds new stem cell therapy to heal hearts

A new $6.9 million grant from the California Institute for Regenerative Medicine (CIRM) will support preclinical development of an investigational cell therapy for the heart created by USC Stem Cell scientists.

5 Nov 2026

Study shows opposite synaptic mechanisms cause identical cognitive deficits

A research team led by Dr. SHENG Nengyin of the Kunming Institute of Zoology (KIZ) of the Chinese Academy of Sciences has reframed ZC4H2-associated rare disorder (ZARD)-a disorder marked by intellectual disability, developmental delays, muscle weakness, and other neurological or physical abnormalities-as a "disease spectrum" rather than a condition driven by a single mechanism.

5 Nov 2026

Vulnerable DNA sites make cancer cells sensitive to PARP inhibitors

A small subset of vulnerable DNA sites can make cancer cells highly sensitive to targeted drugs called PARP inhibitors, a new study shows.

5 Nov 2026

Delivering integrated HIV and substance use services through mobile units could save lives

Results from a clinical trial funded by the National Institutes of Health (NIH) in five major United States cities show that delivering integrated HIV and substance use disorder (SUD) services using peer navigation in mobile medical units reduced all-cause deaths by 71% compared to participants who received peer navigation to community-based services alone.

5 Nov 2026

Graded physical activity prescriptions improve functional outcomes in psychiatry

Most of us have heard the advice so often that it has worn smooth, like a stone in a river: get some exercise. A new peer-reviewed Viewpoint in Brain Health, drawing on randomized trials, meta-analyses, and cohort studies, argues that this familiar sentence has been doing the wrong job.

5 Nov 2026