Ductal Carcinoma News and Research

RSS

Obesity drives distinct molecular pathway toward invasive breast cancer

A novel study has found that obesity is associated with a distinct molecular program driving the transition from early-stage, premalignant breast lesions to invasive breast cancer.

30 Jun 2026

AI image-based risk scores enable dynamic breast cancer assessment

Using artificial intelligence (AI), researchers found that image-based risk scores for breast cancer derived from screening mammograms evolve over time and differ between women who develop cancer and those who do not, opening the door to a new era of dynamic breast cancer risk assessment.

23 Jun 2026

Obesity alters tumor environment promoting invasive breast cancer growth

Obesity may change how early-stage breast cancer becomes invasive, according to a study by University of Oklahoma researchers published in The American Journal of Pathology.

28 May 2026

Research identifies biomarkers in blood to fine-tune breast cancer interventions

Doctors may be able to spare patients unnecessarily aggressive breast cancer treatments by collecting and testing cancer cells in patients' blood, research from the University of Michigan and the University of Kansas suggests.

30 Oct 2025

Genetic risk score can help identify women at higher risk of invasive breast cancer

Studying a person's genetic makeup can predict if they will go on to develop invasive breast cancer after abnormal cells have been found in their breast tissue.

2 Oct 2025

Molecular breast imaging increases overall invasive cancer detection in women with dense breasts

Screening women with dense breasts with both molecular breast imaging (MBI) and digital breast tomosynthesis (DBT) increased overall invasive cancer detection while modestly increasing the recall rate compared with screening only with DBT, according to a new study published today in Radiology, a journal of the Radiological Society of North America.

23 Sep 2025

Hybrid reading strategy for screening mammography reduces radiologist workload

A hybrid reading strategy for screening mammography, developed by Dutch researchers and deployed retrospectively to more than 40,000 exams, reduced radiologist workload by 38% without changing recall or cancer detection rates.

19 Aug 2025

AI algorithm identifies one-third of missed breast cancers in DBT screenings

An AI algorithm for breast cancer screening has potential to enhance the performance of digital breast tomosynthesis (DBT), reducing interval cancers by up to one-third, according to a study published today in Radiology, a journal of the Radiological Society of North America.

29 Jul 2025

ATR FTIR spectroscopy shows high accuracy in breast tissue classification

Histopathology is the gold standard in cancer diagnosis. However, attenuated total reflectance (ATR)-Fourier transform infrared (FTIR) spectroscopy has shown diagnostic potential in other settings.

18 Jul 2025

Caltech researchers develop safer and smarter breast imaging technique

A Caltech-led team has developed a safe, effective, and painless breast imaging technique that incorporates machine learning to help differentiate between suspicious and healthy tissue.

30 Jun 2025

Tumor collagen structure may help explain racial disparities in cancer outcomes

In cancer care, accurate tools for predicting whether a tumor will spread (metastasize) can help patients receive the most appropriate treatments.

15 Jun 2025

New fluorescent tool tracks cancer cell movement in real time

Cancer cell movement during metastasis is a dynamic process regulated by several different signals. However, the way cells receive, process and respond to these signals has been extremely hard to detect, but is now made easier by a new visualisation tool.

2 Jun 2025

Late motherhood and weight gain greatly increase breast cancer risk

Women who experience significant weight gain after the age of 20 and either have their first child after the age of 30 or don't have children are almost three times more likely to develop breast cancer than those who give birth earlier and whose weight remains relatively stable, new research from the UK being presented at this year's European Congress on Obesity (ECO 2025) has found.

11 May 2025

UC San Diego researchers discover new way to predict breast cancer spread

By assessing how "sticky" tumor cells are, researchers at the University of California San Diego have found a potential way to predict whether a patient's early-stage breast cancer is likely to spread.

5 Mar 2025

AI boosts breast cancer detection rates while cutting radiologist workload

AI-supported mammography screening significantly increases breast cancer detection rates while maintaining comparable recall rates, offering a safer and more efficient solution to address radiologist workloads.

8 Jan 2025

Active monitoring for low-risk DCIS results in similar quality of life as standard treatment

Patients with low-risk ductal carcinoma in situ (DCIS) who underwent active monitoring reported comparable physical, emotional, and psychological outcomes to patients who received upfront treatment, according to results from the COMET clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

12 Dec 2024

COMET trial shows active monitoring is noninferior to standard treatment for low-risk DCIS

Among patients with hormone receptor (HR)-positive, HER2-negative, low-risk ductal carcinoma in situ (DCIS), those who underwent active monitoring had similar two-year invasive ipsilateral breast cancer recurrence rates as those who underwent guideline-concordant treatment, according to results from the COMET clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

12 Dec 2024

Tamoxifen lowers breast cancer recurrence in good-risk DCIS patients

For patients with "good-risk" ductal carcinoma in situ (DCIS) who underwent breast- conserving surgery and did not receive radiotherapy, tamoxifen significantly decreased the risk of recurrence in the same breast, according to results presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

12 Dec 2024

Normal breast tissue cells harbor cancer-like genetic abnormalities

A new study from researchers at The University of Texas MD Anderson Cancer Center finds that, in healthy women, some breast cells that otherwise appear normal may contain chromosome abnormalities typically associated with invasive breast cancer. The findings question conventional thinking on the genetic origins of breast cancer, which could influence early cancer detection methods.

20 Nov 2024

Researchers uncover key genes linked to DCIS progression

A team of researchers mapping a molecular atlas for ductal carcinoma in situ (DCIS) has made a major advance toward distinguishing whether the early pre-cancers in the breast will develop into invasive cancers or remain stable.

20 Nov 2024