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Study uses alternative splicing data to predict protein function

A single human gene can produce multiple protein isoforms through alternative splicing, greatly expanding the functional diversity of the proteome.

10 Aug 2026

Circular eccDNA shows potential to predict early-stage LUAD recurrence

LUAD is the most common histological subtype of lung cancer. Although surgery can be curative for patients diagnosed at an early stage, approximately 30%-50% develop recurrence or aggressive metastasis within five years.

10 Aug 2026

Noninvasive sequencing expands prenatal genetic screening capabilities

While non-invasive prenatal testing (NIPT) has revolutionised prenatal diagnostics by allowing the detection of a number of genetic problems in a fetus, it is currently limited and thus misses many genetic causes of abnormalities.

12 Jun 2026

Tracking the aging process across tens of millions of individual cells

While much is mysterious about the aging process, change over time remains its cornerstone. The biological shifts that accompany aging seemingly occur in many cells in the body.

13 May 2026

Study reveals genetic factors influencing SYNGAP1 encephalopathy disease severity

SYNGAP1 encephalopathy is a rare genetic disorder for which there is no treatment, causing epilepsy, intellectual disability, psychomotor delay and, frequently, autism.

22 Apr 2026

Eating peanuts while pregnant may influence how a child’s genes respond to breastfeeding

Maternal peanut and peanut butter consumption during pregnancy and breastfeeding shaped DNA methylation patterns in children, particularly in genes regulating neurodevelopment and inflammation. These findings suggest maternal diet can prime offspring epigenetic sensitivity to breastfeeding duration.

27 Oct 2025

McGill researchers create AI tool to detect hidden disease markers in single cells

McGill University researchers have developed an artificial intelligence tool that can detect previously invisible disease markers inside single cells.

2 Oct 2025

New method advances RNA velocity analysis with spatial and multi batch integration

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it will be and its function.

5 Sep 2025

Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors

A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that are missing in pediatric high-grade glioma tumors but not in normal brain tissues.

18 Aug 2025

New therapeutic approach targets PCSK9 to regulate blood cholesterol levels

When the amount of cholesterol in the blood is too high, hypercholesterolemia can develop, causing serious damage to the arteries and cardiovascular health.

11 Jun 2025

New approach to combat cancer by reactivating natural RNA kill switch

Alternative RNA splicing is like a movie editor cutting and rearranging scenes from the same footage to create different versions of a film.

14 Mar 2025

LUC7 proteins play crucial role in efficient RNA splicing

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut out and the coding portions are spliced back together.

21 Feb 2025

SPLICER shows promise in Alzheimer's and other diseases

A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of Alzheimer's disease, researchers at the University of Illinois Urbana-Champaign report.

23 Dec 2024

Scientists map cancer mutations in EGFR gene, revealing drug resistance paths

Researchers used base and prime editing to uncover new EGFR gene mutations that affect cancer progression and drug resistance, paving the way for personalized treatment strategies.

14 Nov 2024

New study reveals molecular mechanism in Alzheimer's disease

A research team at the Institute of Neurosciences of the University of Barcelona (UBneuro) has led a study describing a new molecular mechanism that affects RNA processing and alters the process of protein synthesis in the brains of Alzheimer's patients.

18 Oct 2024

Exons News and Research

Study uses alternative splicing data to predict protein function

Circular eccDNA shows potential to predict early-stage LUAD recurrence

Noninvasive sequencing expands prenatal genetic screening capabilities

Tracking the aging process across tens of millions of individual cells

Study reveals genetic factors influencing SYNGAP1 encephalopathy disease severity

Eating peanuts while pregnant may influence how a child’s genes respond to breastfeeding

McGill researchers create AI tool to detect hidden disease markers in single cells

New method advances RNA velocity analysis with spatial and multi batch integration

Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors

New therapeutic approach targets PCSK9 to regulate blood cholesterol levels

New approach to combat cancer by reactivating natural RNA kill switch

LUC7 proteins play crucial role in efficient RNA splicing

SPLICER shows promise in Alzheimer's and other diseases

Scientists map cancer mutations in EGFR gene, revealing drug resistance paths

New study reveals molecular mechanism in Alzheimer's disease

New study reveals the genetic cause of Parkinson's disease

Scientists identify over 5,000 genetic variants that enable certain cancers to thrive

Study offers new insights into the evolution of foldable proteins

New study reveals rare genetic variants significantly increase atrial fibrillation risk

UT Health San Antonio researcher wins NIH grant to investigate alcohol-associated liver disease

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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