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Study identifies two opposing molecular patterns in autism models

Autism spectrum disorder (ASD) is associated with more than 1,200 risk genes, raising a fundamental question: Do these diverse genetic changes affect the brain in entirely different ways, or do they converge on shared biological mechanisms?

17 Sep 2026

Researchers uncover possible cause of pain in neurofibromatosis type 1

Researchers at Cincinnati Children's have identified a potential new way to relieve chronic pain linked to neurofibromatosis type 1 (NF1), a genetic condition best known for causing tumors to grow along nerves.

26 May 2026

Detailed cell atlas reveals earliest changes in prostate cancer

Prostate cancer affects one in five Australian men, making it the most common cancer in the country.

25 Mar 2026

Brief oxidative stress promotes brain repair after injury

Oxidative stress is a direct consequence of an excess in the body of so-called "free radicals" – reactive, unstable molecules that contain oxygen.

10 Feb 2026

Replenishing mitochondria significantly reduces chronic nerve pain, research shows

For millions living with nerve pain, even a light touch can feel unbearable. Scientists have long suspected that damaged nerve cells falter because their energy factories known as mitochondria don't function properly.

7 Jan 2026

Oligodendrocyte progenitor cells promote blood vessel growth after stroke

Stroke is a leading cause of death and disability, affecting 1 in 4 people during their lifetime. Stroke happens when blood vessels in the brain get clogged or damaged, impairing blood flow and oxygen supply to the brain, which leads to death of neurons and other brain cells.

30 Oct 2025

Astrocytes revealed as key players in stabilizing long-term emotional memories

Why are we able to recall only some of our past experiences? A new study led by Jun Nagai at the RIKEN Center for Brain Science in Japan has an answer.

15 Oct 2025

How processed red meat might drive neurodegenerative diseases

The relationship between processed red meat and neurodegenerative diseases is complex, with potential risks and protective effects requiring more investigation.

15 Sep 2025

Epigenomic erosion linked to cognitive decline in Alzheimer’s patients

Most people recognize Alzheimer's from its devastating symptoms such as memory loss, while new drugs target pathological aspects of disease manifestations, such as plaques of amyloid proteins.

2 Sep 2025

Brain’s energy control map offers blueprint for next-gen weight loss therapies

Scientists map how the brain integrates hormonal and neural signals from the body to control appetite, energy use, and reward pathways, revealing targets for next-generation anti-obesity drugs. This review highlights the interplay between neuroendocrine circuits, neuroplasticity, and pharmacotherapy for durable, non-aversive weight loss.

11 Aug 2025

Healthy glial cell transplants slow Huntington’s disease progression

Huntington's disease has long defied attempts to rescue suffering neurons. A new study in Cell Reports shows that transplanting healthy human glial progenitor cells into the brains of adult animal models of the disease not only slowed motor and cognitive decline but also extended lifespan.

17 Jun 2025

Understanding the role of astrocytes in depression and neuroinflammation

Major depressive disorder (MDD) is a mental health condition that negatively affects the mood of a person and causes a loss of interest in activities that were previously associated with happiness.

13 Jun 2025

New micropipette allows precise ion delivery to individual brain cells

Researchers at Linköping University have developed a new type of pipette that can deliver ions to individual neurons without affecting the sensitive extracellular milieu.

7 May 2025

Boosting glucose metabolism in glial cells reduces neurodegeneration in fruit flies

Researchers from Tokyo Metropolitan University have discovered that impaired glucose metabolism in glial cells, a type of cell in our nervous system, plays a key role in the degeneration caused by Alzheimer's disease.

5 May 2025

New genetic study reveals hundreds of clues to osteoarthritis

About one in five American adults have osteoarthritis, the most common form of arthritis, according to the Centers for Disease Control and Prevention.

15 Apr 2025

Largest study of osteoarthritis genetics uncovers new drug targets

Osteoarthritis is the leading cause of disability and chronic pain worldwide, affecting an estimated 595 million people globally.

9 Apr 2025

UCLA study reveals key role of mismatch repair genes in Huntington’s disease

A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and triggering downstream pathologies and motor impairment, shedding light on disease mechanisms and potential new ways to develop therapies.

11 Feb 2025

Could autophagy enhancement slow aging and combat Alzheimer's?

How cellular cleanup systems could hold the key to slowing aging and halting neurodegeneration.

9 Jan 2025

Zebrafish study uncovers how ketamine affects brain cells to treat depression

The decades-old anesthetic ketamine could be a game changer for treating severe depression, but there are still many questions about how the drug works, including exactly how it affects the brain's cells and circuits.

17 Dec 2024

Elevated antibody responses to Epstein-Barr virus linked to increased risk of multiple sclerosis

Researchers identified a unique antibody signature against the Epstein-Barr virus protein EBNA1 that correlates with cross-reactive immune responses in multiple sclerosis (MS) patients. This connection provides new insights into how EBV infection may drive MS pathogenesis.

5 Nov 2024