Hormone Replacement Therapy (HRT) News and Research

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Hormone Replacement Therapy (HRT) sometimes called estrogent replacement therapy or ERT, refers to a woman taking supplements of hormones such as estrogen alone or estrogen with another hormone called progesterone (progestin in its synthetic form). HRT replaces hormones that a woman’s body should be making or used to make.

The Moslows' $4 million gift transforms women's health education and research

When Linda Moslow, A16P, A18P, entered perimenopause in her early 40s, she was blindsided. "I'd always been healthy and grounded in wellness," she says. "Suddenly, I couldn't recognize myself." The months of anxiety, sleeplessness, and confusion that followed left her feeling unmoored until she found a team of doctors who helped her understand what was happening.

6 Nov 2025

Hormone replacement therapy may reverse menopause-related immune changes

A study led by researchers at Queen Mary University of London has found that hormone replacement therapy (HRT) may help reverse changes in the immune system caused by menopause, potentially booting immune health.

9 Oct 2025

Study warns women with type 2 diabetes against using oral estrogen therapy

In women with type 2 diabetes (T2D), use of hormone replacement therapy (HRT) skin patches is not associated with a higher risk of blood clots or stroke.

15 Sep 2025

Developing AI-driven stem cell therapies to fight ovarian aging

Ovarian aging, characterized by diminishing egg reserves and quality, affects millions of women worldwide, often leading to infertility.

18 Jul 2025

Night shift work increases risk of severe asthma in women

Women who work night shifts are more likely to suffer with moderate or severe asthma compared to women who work in the daytime, according to a study published today (Monday) in ERJ Open Research.

16 Jun 2025

Early menopause increases risk of fatty liver disease and metabolic disorders

Women who experience menopause before the age of 50 - and especially before the age of 45 - are more likely to develop fatty liver disease and its related metabolic risk factors within one year after menopause, according to research presented at the first Joint Congress between the European Society of Paediatric Endocrinology (ESPE) and the European Society of Endocrinology (ESE).

11 May 2025

Early menopause linked to worse cognitive function in later life

A team of researchers from the Tohoku University Graduate School of Medicine and Tokyo Metropolitan Institute of Medical Science found that women who entered menopause before the age of 40 had worse cognitive outcomes than women who entered menopause after the age of 50.

16 Apr 2025

Study explores how sex chromosomes and hormones influence immune responses

Women have a higher proportion of key immune cells between puberty and menopause, which may be linked to the sex hormone estrogen and explain why they are less susceptible to certain infectious diseases than men, according to a new study led by researchers at UCL.

27 Mar 2025

Specific HRT tablets linked to increased risk of heart disease and blood clots

Certain hormone replacement therapy (HRT) tablets containing both estrogen and progestogen are associated with a higher risk of heart disease and rare but serious blood clots known as venous thromboembolism (VTE) in women around the age of menopause, finds a study from Sweden published by The BMJ today.

28 Nov 2024

History of endometriosis and fibroids linked to higher long-term risk of early death

Researchers examine the impact of endometriosis and uterine fibroids on the risk of early death.

25 Nov 2024

Premature ovarian insufficiency in women linked to greater risk of severe autoimmune conditions

Severe autoimmune conditions such Type I diabetes, Addison's disease, lupus and inflammatory bowel disease, are between two to three times more common in women who have been diagnosed with premature ovarian insufficiency (POI) compared to the general population.

25 Sep 2024

Understanding the impact of BMI on colorectal cancer risk in Asia

Researchers report that body mass index values in Asians population may predict the risk of developing colorectal cancer.

4 Sep 2024

New guidelines can help alleviate unnecessary referrals related to unexpected bleeding

The British Menopause Society (BMS) has launched new, joint guidelines for GPs to help alleviate unnecessary referrals related to unexpected bleeding.

10 Jul 2024

Study reveals benefits of hormone replacement therapy in female pulmonary hypertension patients

The use of hormone replacement therapy (HRT) may be associated with improved pulmonary hypertension in women, according to research presented at the ATS 2024 International Conference. Pulmonary hypertension (PH) is a type of pulmonary vascular disease - disease that affects blood vessels along the route between the heart and lungs.

20 May 2024

Long-term Finnish study explores the association between premature menopause and mortality

Women who enter menopause before the age of 40 are more likely to die young, but may lower their risk with hormone therapy, according to research presented at the 26th European Congress of Endocrinology in Stockholm.

13 May 2024

Korean fermented food Doenjang shows promise in alleviating menopausal symptoms

Study compares the effects of traditional versus commercial Korean Doenjang on menopausal symptoms, finding that traditional variants with high beneficial microorganisms are more effective in reducing these symptoms and improving cardiovascular and gut health.

21 Apr 2024

New approach needed to better prepare and support women during menopause transition, experts say

A new approach to menopause that better prepares and supports women during midlife is needed – going beyond medical treatments, to empower women using high-quality information on symptoms and treatments, empathic clinical care and workplace adjustments as required, says a new four paper Series published in The Lancet.

6 Mar 2024

Psychosocial interventions show promise for managing non-physiological menopausal symptoms

Interventions such as mindfulness and cognitive behavioral therapy (CBT), could be an effective treatment option for menopause-related mood symptoms, memory and concentration problems, finds a new study by UCL researchers.

27 Feb 2024

Study identifies hormonal and reproductive factors for rheumatoid arthritis in women

Early menopause - before the age of 45 - taking hormone replacement therapy (HRT), and having 4 or more children are among several hormonal and reproductive factors linked to a heightened risk of rheumatoid arthritis in women, finds a large long term study published in the open access journal RMD Open.

9 Jan 2024

Prevention of post-menopausal osteoporosis in rats by sesame oil

Study demonstrates that daily supplementation with sesame oil in a rat model effectively prevents post-menopausal osteoporosis by maintaining serum estrogen and aromatase levels, suggesting its potential as a safer alternative to hormone replacement therapy.

4 Jan 2024