Hypomania News and Research

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Probiotics for mental health? A new review finds promising signals and major gaps

This narrative review examines how psychobiotics may influence anxiety, depression, bipolar disorder, and schizophrenia through gut-brain pathways involving neurotransmitters, inflammation, immune regulation, gut barrier function, and stress signaling. Specific Lactobacillus and Bifidobacterium strains showed encouraging effects, but wide differences in strains, doses, populations, and study designs currently limit clinical translation.

28 Aug 2026

Review assesses the efficacy of creatine as an add-on therapy for depression

Walk into any gym supplement aisle and creatine is there, sold by the tub to people chasing bigger muscles. It is one of the most studied compounds in sports science.

30 Jun 2026

Large study uncovers brain network differences in bipolar disorder

New research from the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC has discovered subtle but widespread differences in the brain's communication networks in people with bipolar disorder, offering new insight into how illness severity and treatment may relate to brain wiring.

9 Jun 2026

Scientists find links between bipolar disorder and rare loss-of-function variants in two genes

Scientists at deCODE genetics, a subsidiary of Amgen, reveal today in Nature Genetics associations between bipolar disorder and rare loss-of-function variants in two genes.

25 Mar 2025

Predicting mood episodes with sleep data: A breakthrough for mental health care

Researchers developed a machine-learning model that uses only sleep-wake patterns to predict mood episodes in patients with mood disorders, achieving high accuracy. This approach simplifies real-world mental health monitoring using data from wearables or smartphones.

21 Nov 2024

Brain-stimulation therapy at home reduces major depression symptoms

This study highlights the efficacy of home-based tDCS in treating major depressive disorder, with significant improvements in depressive symptoms and remission.

22 Oct 2024

Daylight heals, night light steals: The surprising link between light exposure and mental health

Researchers find that increased night-time light exposure is linked to higher risks of various psychiatric disorders including depression and anxiety, while more daylight exposure lowers these risks. The large-scale study suggests modulating light patterns could be a non-pharmacological strategy for improving mental health.

12 Oct 2023

Antidepressants may help prevent bipolar depression relapse

Treatment with modern antidepressants may help prevent patients with bipolar disorder from relapsing into a depressive episode, according to an international clinical trial led by researchers at the University of British Columbia.

2 Aug 2023

Study identifies a signature of risk for developing hypomania

Mania, in which mood and energy level are extremely elevated for at least a week, and hypomania, which is less severe and lasts at least four days, are the defining features of bipolar spectrum disorders (BSD) and can be the most disruptive symptoms.

11 Jul 2023

Children and adolescents with persistent high levels of anxiety at greater risk for later psychosis

Children and adolescents who show persistent high levels of anxiety are more likely to become psychotic in their early 20s, according to a new study.

21 Dec 2021

Long-term injectables plus counseling improve medication adherence in bipolar disorder patients

Researchers have found that adherence to taking medications improved in people with bipolar disorder with the use of long-term injectable meds combined with psychosocial intervention.

17 Sep 2021

Six key factors determine medication adherence in people with bipolar disorder

People with bipolar disorder may not take their medication because of side effects, fear of addiction and a preference for alternative treatment - according to research from Norfolk and Suffolk NHS Foundation Trust (NSFT) and the University of East Anglia (UEA).

19 May 2021