Immune System News and Research

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New treatment approach could help people with muscle-invasive bladder cancer live longer

A new treatment approach could help people with an aggressive form of bladder cancer live longer and reduce the chances of their cancer returning or progressing, particularly those who cannot receive standard chemotherapy, according to findings from a large international clinical trial co-led by researchers at the UCLA Health Jonsson Comprehensive Cancer Center.

9 Nov 2026

CAR-T cell therapy shows promising early results for stiff person syndrome

A multicenter clinical trial evaluating chimeric antigen receptor-T cell therapy (CAR-T cell therapy) for stiff person syndrome (SPS), a rare autoimmune neurologic disorder, has produced promising early results.

9 Nov 2026

Space station study tests colorectal cancer tumor avatars in microgravity

Researchers from Wake Forest Institute for Regenerative Medicine (WFIRM) are studying how microgravity affects how models of colorectal cancer cells respond to chemotherapy aboard the International Space Station.

9 Nov 2026

Alliance highlights clinical trials advancing lung cancer detection and care

Lung cancer remains the leading cause of cancer-related deaths in the United States, but advances in early detection and treatment are improving the outlook for patients.

9 Nov 2026

CAR T-cell therapy shows promise for difficult-to-treat lupus

A type of cellular therapy originally developed to treat cancer is showing promise as a potential treatment for people with difficult-to-treat lupus, according to a new study from researchers at Hospital for Special Surgery (HSS).

8 Nov 2026

NIH award supports research into ovarian cancer and neural connections

One of the biggest breakthroughs in modern cancer treatment doesn't attack cancer directly. Instead, immunotherapy harnesses the body's immune system to recognize and destroy cancer cells.

6 Nov 2026

Immune cell differences may explain sex-specific obesity responses

University of California, Riverside scientists have an explanation for why males and females respond differently to obesity.

6 Nov 2026

Two common forever chemicals linked to higher incidence of ER-negative breast cancer

Women with higher blood levels of two common per- and polyfluoroalkyl substances, also familiarly known as PFAS, were more likely to develop estrogen receptor-negative, or ER-negative, breast cancer, according to a new study by the National Institutes of Health (NIH), part of the U.S. Department of Health and Human Services (HHS).

6 Nov 2026

Towards a new approach to treating chronic blood disorders

A previously unrecognised weakness in the immune defenses against certain blood neoplasms could offer a promising target for future treatments.

6 Nov 2026

AI-designed vaccine provides complete protection against diverse bird flu variants

A University of Cambridge team has had a third success with their AI-guided technique for designing vaccines against highly infectious viruses that threaten animal and human health.

5 Nov 2026

Anti-PEG antibodies drive contrasting liposome skin toxicity across species

This new article publication from Acta Pharmaceutica Sinica B discusses how anti-polyethylene glycol antibodies affect the movement of stealth liposomes from blood into skin, revealing contrasting distribution and toxicity patterns in mice and rats.

5 Nov 2026

Three-drug combination remodels immune environment in gastric cancer

A triplet combination therapy can remodel the tumor microenvironment in patients with advanced gastric cancer and shows a promising safety profile, according to results from a new phase 2 clinical trial.

5 Nov 2026

Workplace exposure to petroleum-based lubricants linked to higher MS risk

Exposure to petroleum-derived lubricants at work, including engine oil, hydraulic oil and cutting fluids used to cool or lubricate metal during metalworking, is associated with higher odds of multiple sclerosis (MS), according to a study published November 4, 2026, in Neurology, the medical journal of the American Academy of Neurology.

4 Nov 2026

New method detects lung antibodies through non-invasive exhaled breath

For the first time, researchers have succesfully measured antibodies against specific respiratory viruses in exhaled air. This is shown in a new study involving, amongst others, the Karolinska Institutet, published in eBioMedicine.

4 Nov 2026

Protein DUSP4 prevents immune cell exhaustion in colorectal cancer

The immune system has powerful cells that can recognize and destroy cancer, but this ability can gradually wane when the cells reside within a tumor.

4 Nov 2026

Disrupting three Salmonella genes weakens bacterial biofilm defenses

A major challenge to combating bacterial infections is the formation of biofilms-protective structures that allow bacteria to adhere to surfaces and reproduce, increasing their chances of survival even when challenged with antibiotics and the host's immune system.

4 Nov 2026

AlphaFold3 reveals molecular interactions driving T cell recognition

Researchers at the Translational Genomics Research Institute (TGen), part of City of Hope, have developed a new approach using the artificial intelligence platform AlphaFold3 to predict whether a T cell receptor will recognize a specific antigen based solely on its genetic sequence.

3 Nov 2026

Scientists use extracellular vesicles to track source of chronic inflammation

A new technique to diagnose chronic inflammation developed at Nagoya University can read information from the surface and within individual extracellular vesicles in blood and urine.

3 Nov 2026

Alliance for Clinical Trials in Oncology highlights key role of clinical research in advancing men's cancer care

Every November, millions worldwide grow mustaches and join Movember, a global movement launched in 2003 to spark conversations about men's health, including prostate cancer, testicular cancer, and mental health.

3 Nov 2026

Key innate immune protein regulates cholesterol and influences cancer treatment resistance

Scientists at the University of North Carolina Lineberger Comprehensive Cancer Center have discovered an unexpected role for a key innate immune protein, revealing how it helps regulate cholesterol levels inside cells and influences tumor growth and treatment response.

3 Nov 2026