Immune System News and Research

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Obesity disrupts ILC2 metabolism through increased fatty acid uptake

Recent lifestyle changes, such as reduced physical activity and increased consumption of energy-dense, processed foods, have dramatically increased the prevalence of obesity and diabetes worldwide.

23 Sep 2026

Discovery of receptor-free signaling reveals better targets for treating autoimmune diseases

Our understanding of how cells interact with each other has been driven for decades by the central concept of receptor-mediated signal transduction.

23 Sep 2026

CAR T-cell therapy enables safe pregnancies in autoimmune patients

Autoimmune diseases such as systemic lupus erythematosus mainly affect young women, often in a phase of their lives where they would like to have children.

22 Sep 2026

MLC1 auto-antibodies identified as possible trigger for NMOSD-like diseases

NMOSD is an inflammatory autoimmune disorder that damages support and supply cells in the central nervous system, known as astrocytes.

22 Sep 2026

Study identifies B cells as drivers of immunotherapy-related colitis

Researchers at The University of Texas MD Anderson Cancer Center have identified a previously unknown role for B cells, which are adaptive immune cells, in triggering and sustaining colitis occurring as a side effect of immune checkpoint inhibitors, a widely used form of cancer immunotherapy.

22 Sep 2026

Garvan research reveals hidden inflammation behind high colon cancer risk

New research from the Garvan Institute of Medical Research has revealed for the first time that two closely related bowel diseases, currently treated in the same way, are fundamentally different.

22 Sep 2026

Congo faces unprecedented Ebola outbreak without approved vaccine protection

As the Ebola outbreak spreads unabated in the Democratic Republic of the Congo (DRC), vaccine developers are scrambling to develop and test a vaccine candidate that will target the species at its center.

21 Sep 2026

Stalled gut microbiome development triples risk for type 1 diabetes in children

Type 1 diabetes affects more than 9 million people worldwide, including 1.8 million children and adolescents.

21 Sep 2026

MIT researchers develop noninvasive way to spot aging zombie cells

As we age, some of the cells in our body enter a state of senescence, in which they stop dividing but do not die. Those senescent cells can contribute to age-related disorders such as cancer, tissue degeneration, and inflammatory diseases.

21 Sep 2026

New mRNA vaccine expands flu protection options for older adults

Every fall, millions of Americans heed the call to get their annual flu shot. Getting vaccinated reduces the risk of severe illness, hospitalization, and death from influenza.

20 Sep 2026

HIV awareness emphasizes prevention, treatment and healthy aging

About 1.2 million people in the United States are living with HIV, or human immunodeficiency virus. Because of major advances in medical treatment and technology, people with HIV are living long, healthy lives.

18 Sep 2026

Y chromosome loss creates hidden cancer vulnerability in men

A study initiated by a University of Arizona Cancer Center physician-scientist Dr. Dan Theodorescu revealed that the loss of the Y chromosome in men's body tissue could pave the way for cancer to develop in that tissue.

18 Sep 2026

SARS-CoV-2 protein ORF8 drives macrophage infection and lung inflammation

In the sickest COVID-19 patients, the SARS-CoV-2 virus doesn't just cause severe damage by directly infecting airway cells.

18 Sep 2026

B cells may play a role in triggering immunotherapy-related colitis

18 Sep 2026

Antibody therapy teaches the immune system to control HIV

There is no cure for HIV. While scientists have made considerable progress in controlling the infection, patients still must take daily antiretroviral medication for the rest of their lives.

18 Sep 2026

Chronic stress and inflammation cause silent structural heart damage

Chronic stress from people's everyday lives may be causing lasting structural changes to the heart, harming health and reducing life expectancy.

18 Sep 2026

Can maternal diet prevent infant food allergy? A large trial puts eggs and peanuts to the test

A large Australian randomized trial of 2,137 pregnant women tested whether substantially increasing egg and peanut consumption during pregnancy and breastfeeding could prevent food allergy in infants with a strong family history of allergic disease. Higher maternal intake did not significantly reduce IgE-mediated egg or peanut allergy at 1 year, although the lower-than-expected allergy rate limited statistical power and the results could not exclude a clinically important benefit.

17 Sep 2026

Scientists reveals how cancer-causing p53 mutations remain invisible to the immune system

One of the biggest challenges in cancer immunotherapy may not be that immune cells are too weak, but that some tumors give them too little to see.

17 Sep 2026

Innate immune system variations determine vaccine side effects

Redness and pain at the injection site, fever, fatigue or headaches: vaccines can cause side effects, but their frequency and severity vary considerably from person to person.

17 Sep 2026

Salk scientists demonstrate B cells directly enhance killer T cell function

Cancer is the second leading cause of death in the United States, according to a 2026 Cancer Research Institute report. Cancer biologists are keenly aware of this statistic, as it drives them to innovations that revolutionize cancer care-innovations like immunotherapy.

17 Sep 2026