Induced Pluripotent Stem Cells News and Research

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Scientists develop lab-grown heart tissue model for heart failure

Scientists study the underlying causes of a disease or test new potential drugs in animal models or cells obtained from human biopsy specimens before clinical trials.

2 Sep 2026

Bridging science and family story to understand schizophrenia origins

Twin studies have placed the heritability of schizophrenia at roughly eighty percent for decades. Concordance between identical twins, who share the entire genome, does not reach fifty percent. Both figures are well established, and they do not fit together comfortably.

2 Sep 2026

Stanford scientists develop an ultracompact gene activation tool

The ability to precisely adjust the expression of genes inside the human body - ramping up protective ones and tamping down harmful ones - holds enormous potential for treating and preventing disease.

28 Aug 2026

Scalable stem cell method advances off-the-shelf CAR-T therapies

Researchers at the Center for Regenerative Medicine (CReM) at Boston Medical Center (BMC) and Boston University (BU) have developed a scalable method for generating CD4+ helper T cells from induced pluripotent stem cells (iPSCs), overcoming a longstanding challenge in the development of stem cell-based immunotherapies.

27 Aug 2026

Multi-organ chip uncovers key mechanisms behind cancer metastasis

Cancer spreading beyond the primary tumor – a process known as metastasis – is responsible for at least two-thirds of cancer deaths.

19 Aug 2026

Mass-producible immune cells fight solid human tumors in mice

Off-the-shelf and mass-producible immune cells fight solid human tumors engrafted into mice. The Kobe University development is a significant contribution towards faster and cheaper cancer immunotherapy.

23 Jul 2026

Researchers use canine iPSCs to generate red blood cell-like cells

Blood transfusions are crucial in human and veterinary medicine, yet human blood reserves are in constant need of donors while blood bank systems in veterinary care are nearly non-existent.

19 Jul 2026

New genetic reference map accelerates human stem cell research

A team led by bioengineers at the University of California San Diego has developed a genome-scale reference map that details how individual genes control the functions and identities of human stem cells.

13 Jul 2026

Off-the-shelf CAR T therapy targets treatment-resistant systemic sclerosis

Today at ISSCR 2026, new preliminary clinical data was presented evaluating an induced pluripotent stem cell (iPSC)-derived CAR T-cell therapy for patients with treatment-resistant systemic sclerosis, a rare autoimmune disease with high mortality.

9 Jul 2026

Stem cell study uncovers molecular pathway for enamel regeneration

Tooth enamel is the hardest substance in the human body, yet once damaged, it cannot regenerate naturally.

9 Jul 2026

Researchers advance fertility options for childhood cancer survivors

Researchers at Karolinska Institutet have demonstrated that it is possible to create early germ cells from preserved testicular tissue of young boys facing cancer therapy.

3 Jul 2026

Duke engineers grow retinal blood vessel cells from pluripotent stem cells

Biomedical engineers at Duke University have used induced pluripotent stem cells (iPSCs) to grow specialized blood vessel cells critical to retinal health for the first time.

30 Jun 2026

New diagnostic tool bypasses blood-brain barrier to detect autism early

A study published in NeuroMarkers showed that a nanosensor can measure nitric oxide (NO) from patient-derived stem cells to distinguish autism spectrum disorder (ASD) from intellectual disability (ID), even when both conditions share the exact same genetic mutation.

30 Jun 2026

New drug candidate reduces toxic protein clumps of Huntington's disease

An experimental drug has been shown to alleviate symptoms of Huntington's disease and extend lifespan in mouse models. Further studies are required to determine whether these results may also apply to humans.

29 Jun 2026

Scaling organoid workflows with automation and AI for drug discovery

Discover how automation, AI, and organoid technologies are improving drug discovery through scalable workflows.

From Molecular Devices UK Ltd 29 Jun 2026

Cerebral organoid model offers insights into the mechanisms of Ebola virus persistence

Following infection, Ebola virus can survive unnoticed in the human body for months or even years, hiding in areas with little immune surveillance like the central nervous system.

17 Jun 2026

Magnetic microrobots deliver stem cells to heal spinal cord injuries

A research team from ETH Zurich and the University of Zurich (UZH) has developed a novel approach to treating spinal cord injuries: controllable microrobots deliver stem cells directly to the site of an injury, where they promote nerve cell regeneration.

2 Jun 2026

New magnetic particle imaging ensures precision cell therapy injection tracking

Scientists at Johns Hopkins Medicine say they used a form of magnetic imaging to track cell therapy injections commonly used to treat certain autoimmune diseases and cancers.

2 Jun 2026

Cincinnati scientists grow larger gut organoids with self-developing nerve cells

Thanks to special 3D-printed scaffolding trays designed by experts at Cincinnati Children's, researchers can now produce larger versions of functional human gut organoids twice as fast as previous methods-and these organoids grow their own nerve cells.

22 May 2026

Recent advancements in the development of models to study primary sclerosing cholangitis

Primary sclerosing cholangitis (PSC) is a rare non-communicable disorder that affects the liver. Chronic inflammation in and around the bile duct is followed by the development of fibrotic obstructions within the duct, causing bile to accumulate within the liver.

19 May 2026