Infectious Diseases News and Research

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Single amino acid change alters Andes virus protein behavior

Mount Sinai researchers have identified a single amino acid difference between rodent- and human-derived Andes virus isolates that changes how a key viral protein behaves inside human cells.

6 Nov 2026

Routine pediatric lung therapies do not improve ventilator-free days

Results from the largest international clinical trial of its kind show that early, routine use of prone positioning and/or high-frequency oscillatory ventilation (HFOV) do not increase ventilator-free days for children with pediatric acute respiratory distress syndrome (PARDS).

6 Nov 2026

Medical societies unify to endorse evidence-based respiratory vaccine guidance

Hoping to provide much-needed guidance to clinicians treating patients with lung disease and to promote respiratory health, the Vaccine Guidance Review Panel, a multi-medical society effort, announced its endorsement of influenza, RSV and COVID-19 recommendations for adults and children.

5 Nov 2026

AI-designed vaccine provides complete protection against diverse bird flu variants

A University of Cambridge team has had a third success with their AI-guided technique for designing vaccines against highly infectious viruses that threaten animal and human health.

5 Nov 2026

Delivering integrated HIV and substance use services through mobile units could save lives

Results from a clinical trial funded by the National Institutes of Health (NIH) in five major United States cities show that delivering integrated HIV and substance use disorder (SUD) services using peer navigation in mobile medical units reduced all-cause deaths by 71% compared to participants who received peer navigation to community-based services alone.

5 Nov 2026

Comprehensive genetic map offers new hope for tuberculosis treatments

Rockefeller scientists have created the most comprehensive map to date of how essential genes interact in Mycobacterium tuberculosis (Mtb), the bacterium responsible for tuberculosis (TB).

4 Nov 2026

AlphaFold3 reveals molecular interactions driving T cell recognition

Researchers at the Translational Genomics Research Institute (TGen), part of City of Hope, have developed a new approach using the artificial intelligence platform AlphaFold3 to predict whether a T cell receptor will recognize a specific antigen based solely on its genetic sequence.

3 Nov 2026

Nurses need more visible roles in the modern 'One Health' governance

Nurses may be one of the most important parts of the health care workforce – yet their contribution is overlooked, according to a new paper examining the profession's place in the growing 'One Health' movement to connect human, animal and environmental health.

3 Nov 2026

Gene therapy successfully corrects genetic defect in alpha-1 antitrypsin deficiency

In a landmark achievement in the field of genetic medicine, researchers have reported the very first published case in a peer-reviewed journal of a successful clinical treatment of a patient with alpha-1 antitrypsin deficiency (PiZZ) using in vivo gene therapy.

2 Nov 2026

Two rounds of prenatal STI screening lower preterm birth risk

Screening and treating pregnant patients for three common sexually transmitted infections (STIs) twice during pregnancy was associated with a 23 percent lower risk of preterm birth compared with standard care, according to a randomized clinical trial published in Clinical Infectious Diseases from researchers at the University of Pennsylvania and University of Southern California.

29 Oct 2026

COMPASS pathway helps regulatory T cells prevent intestinal inflammation

Trillions of bacteria live in the human gut without triggering an immune response. Scientists at St. Jude Children's Research Hospital have now discovered a gene-regulatory pathway that helps maintain this delicate balance.

28 Oct 2026

Study shows income gaps drive disparities in universal healthcare access

Higher levels of human development are associated with better universal health coverage worldwide, and disparities in coverage between income groups are generally larger than disparities between world regions.

28 Oct 2026

Opioid drop drives decline in drug-related heart infection hospitalizations

A new national study found that hospitalizations for serious heart infections associated with drug use are declining after years of increases, driven largely by a decrease in opioid-associated cases.

27 Oct 2026

NEC contributes to AI powered vaccine design through the EU funded PREPAIR VAC pandemic preparedness project

NEC Corporation today announced its participation in PREPAIR VAC, a Horizon Europe–funded research project aimed at strengthening pandemic preparedness through the application of artificial intelligence (AI) in vaccine design.

27 Oct 2026

Clinical trial establishes effective HIV dosing regimen for full-term newborns

An international study conducted through the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network including researchers at the University of California San Diego helped inform the U.S. Food and Drug Administration's (FDA) recent approval of dolutegravir, a second-generation integrase inhibitor, for the treatment of human immunodeficiency virus (HIV-1) in newborns from birth.

22 Oct 2026

Unstable immune cells linked to severe cancer immunotherapy side effects

Scientists at the University of Pittsburgh uncovered the unstable immune cells that can cause up to 40% of immunotherapy patients to experience serious side effects and showed that diet and microbiome composition influence the side effect's severity.

22 Oct 2026

Large-scale meteorological patterns linked to Ebola virus outbreaks

A study led by the University of Malaga has shown that outbreaks of Ebola virus do not occur randomly over time; rather, their appearance is linked to specific large-scale meteorological patterns, even with oscillations occurring in regions thousands of miles away from Central Africa, where they are currently suffering from an epidemic of this disease, which can be fatal.

22 Oct 2026

Review offers guidance for managing recurrent catheter-related bloodstream infections

Patients who depend on long-term intravenous catheters for chemotherapy, hemodialysis, intravenous nutrition and other essential therapies face an ongoing risk of catheter-related bloodstream infections, a potentially life-threatening complication that can be difficult to manage when the device remains necessary for care.

22 Oct 2026

$52 million study to investigate why some infants develop lasting lung infections

A Michigan Medicine-led research consortium has secured approval for up to $52 million in federal funding to launch a multicenter study examining why some young children recover fully from viral lower respiratory tract infections while others develop severe illness or lasting problems such as asthma.

20 Oct 2026

Mount Sinai wins NIH grant to test community-based hypertension care model in rural Ghana

Researchers at the Icahn School of Medicine at Mount Sinai have received a $3.3 million, five-year grant from the National Heart, Lung, and Blood Institute, part of the National Institutes of Health, to test an innovative community-based primary care model for high blood pressure in rural Ghana.

15 Oct 2026

Infectious Diseases News and Research

Single amino acid change alters Andes virus protein behavior

Routine pediatric lung therapies do not improve ventilator-free days

Medical societies unify to endorse evidence-based respiratory vaccine guidance

AI-designed vaccine provides complete protection against diverse bird flu variants

Delivering integrated HIV and substance use services through mobile units could save lives

Comprehensive genetic map offers new hope for tuberculosis treatments

AlphaFold3 reveals molecular interactions driving T cell recognition

Nurses need more visible roles in the modern 'One Health' governance

Gene therapy successfully corrects genetic defect in alpha-1 antitrypsin deficiency

Two rounds of prenatal STI screening lower preterm birth risk

COMPASS pathway helps regulatory T cells prevent intestinal inflammation

Study shows income gaps drive disparities in universal healthcare access

Opioid drop drives decline in drug-related heart infection hospitalizations

NEC contributes to AI powered vaccine design through the EU funded PREPAIR VAC pandemic preparedness project

Clinical trial establishes effective HIV dosing regimen for full-term newborns

Unstable immune cells linked to severe cancer immunotherapy side effects

Large-scale meteorological patterns linked to Ebola virus outbreaks

Review offers guidance for managing recurrent catheter-related bloodstream infections

$52 million study to investigate why some infants develop lasting lung infections

Mount Sinai wins NIH grant to test community-based hypertension care model in rural Ghana

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