Intestinal Disease News and Research

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Could your birth characteristics influence colorectal cancer risk?

A California study links birth and parental factors to early-onset colorectal cancer risk, highlighting male sex and Hispanic ethnicity as key contributors.

26 Jun 2026

Noninvasive technology detects early intestinal disease in premature infants

A new noninvasive technology, called broadband optical spectroscopy (BOS), has promise to reliably detect necrotizing enterocolitis (NEC) in premature infants at earlier stages, before this devastating intestinal disease progresses enough to be visible on x-ray, according to a first-in-human study from Ann & Robert H. Lurie Children's Hospital of Chicago published in the Journal of Pediatric Surgery.

5 Jun 2026

Advancing stem cell regeneration through animal-free culture systems

Intestinal Stem Cells (ISCs) derived from a patient's own cells have garnered significant attention as a new alternative for treating intractable intestinal diseases due to their low risk of rejection.

30 Dec 2025

Gut neurons control immunity attack or repair

Beneath the surface of your gut lies a vast network of neurons—as many as in your spinal cord. New research from the Champalimaud Foundation (CF) in Lisbon shows that in mice this "second brain" helps decide whether the immune system should go into attack mode or start repairing tissue.

24 Nov 2025

Psoriasis-linked gene mutation may also play a surprising role in gut health

A mutation previously linked to skin disorders like psoriasis may also play a surprising role in gut health, according to new research published by scientists at VIB-UGent and colleagues from UGent, the University of Barcelona, and University College London.

23 Oct 2025

ANU researchers develop cholesterol-based trojan horse method to target malaria parasites

More than a quarter of Australians over the age of 50 take cholesterol-lowering drugs to prevent heart disease and strokes, but our bodies also need cholesterol to survive.

13 Aug 2024

Probiotic LGG reduces necrotizing enterocolitis risk in preterm infants

The strain-specific effects of Lactobacillus rhamnosus GG (LGG) in preterm infants through a systematic review and meta-analysis of randomized controlled trials (RCTs) and non-RCTs.

31 Jul 2024

Investigational protein replacement protects neonatal mice from deadly intestinal disease

Scientists from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago and colleagues found that an investigational protein replacement – recombinant human insulin-like growth factor 1 and its binding protein-3 (rhIGF-1/BP3) – protected neonatal mice from necrotizing enterocolitis (NEC), a deadly intestinal disease that often strikes extremely premature infants.

28 Feb 2024

Anti-CTLA-4 nanobodies offer promising strategy to prevent colitis in cancer immunotherapy

Microbiota-reactive T cells trigger colitis in mice harboring the microbiota of wild-caught mice following CTLA-4 blockade, according to a new study that reveals a major mechanism by which anti-CTLA-4 antibodies induce inflammatory toxicities during antitumor immune checkpoint inhibitor therapies.

4 Jan 2024

Fiber-free diet key to treating childhood Crohn's disease, new study finds

Research reveals how a fiber-free diet in Exclusive Enteral Nutrition (EEN) helps treat Crohn's disease in children by affecting the intestinal pathobiont Mucispirillum schaedleri. It shows that this diet alters gut microbiota, reducing Mucispirillum's pathogenicity and aiding in managing colitis.

26 Nov 2023

Gut microbes play a starring role in insulin resistance, opening doors for new diabetes treatments

The study reveals a strong association between gut microbial carbohydrate metabolism and insulin resistance, pointing to gut microbes as a key player in metabolic syndrome and type 2 diabetes. Targeting these microbial activities could offer a new therapeutic pathway for improving insulin resistance and overall metabolic health.

4 Sep 2023

Stem cells offer new hope for Crohn's disease treatment

Research from Ann & Robert H. Lurie Children's Hospital of Chicago found that direct injection of neonatal mesenchymal stem cells, derived from heart tissue discarded during surgery, reduces intestinal inflammation and promotes wound healing in a mouse model of Crohn's disease-like ileitis, an illness marked by chronic intestinal inflammation and progressive tissue damage.

28 Jul 2023

Inherited genes linked to higher risk for diverticular disease of intestine

University of Queensland researchers have used genetics to reveal that much of the risk of developing a common and sometimes fatal intestinal disease is inherited.

4 Jul 2023

Mental health profoundly impacts inflammatory responses in the body

Study uncovered mechanisms by which psychological stress affects bowel inflammation.

30 May 2023

Study: Black infants disproportionately die from necrotizing enterocolitis compared to White babies

A study published in JAMA Network Open has found that in the US between 1999 and 2020, Black infants disproportionately died from necrotizing enterocolitis compared to White infants, despite overall improvements in the rates of death from the disease.

3 Mar 2023

Intestinal Disease News and Research

Could your birth characteristics influence colorectal cancer risk?

Noninvasive technology detects early intestinal disease in premature infants

Advancing stem cell regeneration through animal-free culture systems

Gut neurons control immunity attack or repair

Psoriasis-linked gene mutation may also play a surprising role in gut health

ANU researchers develop cholesterol-based trojan horse method to target malaria parasites

Probiotic LGG reduces necrotizing enterocolitis risk in preterm infants

Investigational protein replacement protects neonatal mice from deadly intestinal disease

Anti-CTLA-4 nanobodies offer promising strategy to prevent colitis in cancer immunotherapy

Fiber-free diet key to treating childhood Crohn's disease, new study finds

Gut microbes play a starring role in insulin resistance, opening doors for new diabetes treatments

Stem cells offer new hope for Crohn's disease treatment

Inherited genes linked to higher risk for diverticular disease of intestine

Mental health profoundly impacts inflammatory responses in the body

Study: Black infants disproportionately die from necrotizing enterocolitis compared to White babies

Strong connection between inflammatory bowel disease and periodontitis

Gut colonization by proteobacteria modulates mice’s neurobehavioral response to cocaine

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

Carbon monoxide foam in the fight against inflammation

New clinical trial to test third dose of COVID-19 vaccine for immunocompromised people

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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