Invasive Ductal Carcinoma News and Research

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Obesity drives distinct molecular pathway toward invasive breast cancer

A novel study has found that obesity is associated with a distinct molecular program driving the transition from early-stage, premalignant breast lesions to invasive breast cancer.

30 Jun 2026

AI image-based risk scores enable dynamic breast cancer assessment

Using artificial intelligence (AI), researchers found that image-based risk scores for breast cancer derived from screening mammograms evolve over time and differ between women who develop cancer and those who do not, opening the door to a new era of dynamic breast cancer risk assessment.

23 Jun 2026

Obesity alters tumor environment promoting invasive breast cancer growth

Obesity may change how early-stage breast cancer becomes invasive, according to a study by University of Oklahoma researchers published in The American Journal of Pathology.

28 May 2026

Molecular breast imaging increases overall invasive cancer detection in women with dense breasts

Screening women with dense breasts with both molecular breast imaging (MBI) and digital breast tomosynthesis (DBT) increased overall invasive cancer detection while modestly increasing the recall rate compared with screening only with DBT, according to a new study published today in Radiology, a journal of the Radiological Society of North America.

23 Sep 2025

Hybrid reading strategy for screening mammography reduces radiologist workload

A hybrid reading strategy for screening mammography, developed by Dutch researchers and deployed retrospectively to more than 40,000 exams, reduced radiologist workload by 38% without changing recall or cancer detection rates.

19 Aug 2025

AI algorithm identifies one-third of missed breast cancers in DBT screenings

An AI algorithm for breast cancer screening has potential to enhance the performance of digital breast tomosynthesis (DBT), reducing interval cancers by up to one-third, according to a study published today in Radiology, a journal of the Radiological Society of North America.

29 Jul 2025

ATR FTIR spectroscopy shows high accuracy in breast tissue classification

Histopathology is the gold standard in cancer diagnosis. However, attenuated total reflectance (ATR)-Fourier transform infrared (FTIR) spectroscopy has shown diagnostic potential in other settings.

18 Jul 2025

Caltech researchers develop safer and smarter breast imaging technique

A Caltech-led team has developed a safe, effective, and painless breast imaging technique that incorporates machine learning to help differentiate between suspicious and healthy tissue.

30 Jun 2025

Tumor collagen structure may help explain racial disparities in cancer outcomes

In cancer care, accurate tools for predicting whether a tumor will spread (metastasize) can help patients receive the most appropriate treatments.

15 Jun 2025

New fluorescent tool tracks cancer cell movement in real time

Cancer cell movement during metastasis is a dynamic process regulated by several different signals. However, the way cells receive, process and respond to these signals has been extremely hard to detect, but is now made easier by a new visualisation tool.

2 Jun 2025

AI improves breast cancer staging by analyzing chromatin images

Researchers at the Paul Scherrer Institute PSI and the Massachusetts Institute of Technology MIT are using artificial intelligence to improve the categorization of breast cancer.

24 Jul 2024

Pembrolizumab enhances breast cancer treatment regardless of age or menopausal status

New data from the KEYNOTE-756 phase 3 clinical trial show that adding the immunotherapy drug, pembrolizumab, to chemotherapy before and after surgery for breast cancer leads to better outcomes for patients regardless of their age or menopausal status.

20 Mar 2024

Evaluating the effectiveness and safety of single-port robot-assisted technique in nipple-sparing mastectomy procedures

Researchers evaluated the safety and feasibility of a single-port (SP) robotic-assisted approach for performing nipple-sparing mastectomies (NSM).

19 Jan 2024

Unraveling the role of HER2 mutant alleles in breast cancer

A new editorial paper was published in Oncotarget's Volume 14 on October 31, 2023, entitled, "The uncharted role of HER2 mutant alleles in breast cancer."

6 Nov 2023

Healthy breast fat may protect against invasive breast cancer

Researchers have found a possible explanation as to why higher breast density and older age increase the risk of breast cancer.

17 Jul 2023

Study finds ultrasound as an effective standalone diagnostic method for focal breast complaints

Ultrasound is an effective standalone diagnostic method in patients with focal breast complaints, according to a study published in Radiology, a journal of the Radiological Society of North America.

4 Apr 2023

Advancements in understanding and treating breast cancer

Researchers describe recent advancements in breast cancer research.

26 Mar 2023

Study finds better breast cancer screening outcomes with tomosynthesis than mammography

In a study of over a million women, digital breast tomosynthesis (DBT) showed improved breast cancer screening outcomes over screening with standard digital mammography alone.

14 Mar 2023

Multi-center analysis shines light on invasive lobular carcinoma

A multi-center analysis of patients with invasive lobular carcinoma, or ILC - the second most common histological subtype of invasive breast cancer in the U.S. - showed that, despite its prevalence, ILC is detected later and has worse outcomes than the predominant subtype of invasive breast cancer, known as invasive ductal carcinoma (IDC), or no special type.

14 Oct 2022

Breast MRI may help stratify the risk of second breast cancer

Breast tissue features apparent on MRI are linked with future second breast cancer risk in women with a personal history of breast cancer, according to a study published in Radiology, a journal of the Radiological Society of North America (RSNA).

30 Aug 2022