Juvenile Idiopathic Arthritis News and Research

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Juvenile idiopathic arthritis (JIA) is the name given to a group of conditions characterized by joint inflammation or arthritis, occurring first before the age of 16.

Pediatric rheumatic diseases have unique genetic architecture compared to adults

Researchers from Children's Hospital of Philadelphia (CHOP) have found that pediatric-onset rheumatic and inflammatory diseases have distinct genetic architecture compared with adults.

12 Aug 2026

EULAR 2026 highlights rising comorbidity risks in rheumatic disease

People with rheumatic and musculoskeletal diseases (RMD) are at risk of a number of comorbidities, from cardiovascular diseases to cognitive impairment and fractures.

4 Jun 2026

EULAR proposes new guidance to assess disease activity in adult-onset Still’s disease

EULAR - The European Alliance of Associations for Rheumatology - has identified an unmet clinical need around the assessment of disease activity in people with adult-onset Still's disease.

12 Dec 2025

Antibiotics in pregnancy and infancy do not raise autoimmune disease risk in children

A nationwide Korean cohort study found that antibiotic use during pregnancy or early infancy did not increase overall risk of childhood autoimmune diseases. Subgroup signals for Crohn’s disease and autoimmune thyroiditis warrant cautious follow-up.

25 Aug 2025

New study maps cellular fingerprints driving childhood arthritis

A new groundbreaking study by researchers from University of Birmingham, UCL, Great Ormond Street Hospital and Birmingham Children's Hospital has revealed important clues into what is driving disease in children with arthritis.

2 Jul 2025

Single-cell transcriptomes of immune cells offer insight into juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIA), a type of arthritis commonly occurring in children, is a chronic, inflammatory condition that affects the joints, causing pain, swelling, stiffness, and limiting the range of motion.

2 Jul 2025

Interferon pathway genes linked to treatment success in juvenile arthritis

A set of genes that could be used to help doctors predict which children will respond well to treatment for juvenile idiopathic arthritis (JIA) have been identified by researchers at UCL and Great Ormond Street Hospital for Children (GOSH), who are part of the CLUSTER Consortium.

18 Jun 2025

Immunotherapy may be an effective treatment strategy for heart failure

A new study from Washington University School of Medicine in St. Louis suggests that a type of immunotherapy - similar to that approved by the Food and Drug Administration (FDA) to treat inflammatory conditions such as arthritis - also may be an effective treatment strategy for heart failure.

23 Oct 2024

Steritas' Pediatric Glucocorticoid Toxicity Index applied in clinical trial to assess steroid-toxicity

Steritas LLC., a company dedicated to enhancing patient care for steroid-treated patients announced that Alder Hey Children’s NHS Foundation Trust, and the Liverpool Clinical Trials Centre will apply its Steritas Pediatric Glucocorticoid Toxicity Index (pGTI) in a clinical trial to compare efficacy, safety and cost-effectiveness of intravenous versus oral glucocorticoids (steroids) for children and young people with Juvenile Idiopathic Arthritis (JIA).

From Steritas LLC 25 Sep 2024

Young people with chronic pain more likely to have clinical anxiety or depression

Young people with chronic pain are three times more likely than their peers to also have clinical anxiety or depression, a new review has found.

9 Sep 2024

Scurvy on the rise in the United States: Pediatric cases triple in five years

Researchers found that pediatric scurvy cases tripled from 2016 to 2020, highlighting a significant rise in incidence, particularly among low-income, male, and autistic children.

19 Jul 2024

Tackling challenges in childhood arthritis transition to adult care

Rheumatological diseases can affect people during childhood, the most common being juvenile idiopathic arthritis (JIA).

14 Jun 2024

Multi-center study validates systemic score in identifying high-risk patients with Still's disease

A multi-centre, observational, prospective study was designed to evaluate the clinical usefulness of the systemic score in predicting life-threatening evolution – defined as the development of macrophage activation syndrome (MAS) and/or mortality.

12 Jun 2024

Linking perinatal events to juvenile idiopathic arthritis-uveitis

Researchers investigate perinatal events associated with the manifestation of juvenile idiopathic arthritis and the development of JIA-uveitis.

20 Oct 2023

Comparative genomic analysis between systemic juvenile rheumatoid arthritis and type 1 diabetes

Shared genetic markers and immune system involvement in sJRA and T1D.

15 Sep 2023

Study discovers method to classify febrile illness with a single blood sample

Researchers trained machine learning (ML) models to analyze RNA molecular signatures in patients’ blood.

28 Aug 2023

Arthritis affects 220,000 children and teens, according to a new CDC study

In a recent MMWR published by the United States CDC, researchers combine survey data from the NSCH collected over a five-year period to estimate the prevalence of arthritis.

26 Jul 2023

PCORI awards $208 million to fund 17 new comparative clinical effectiveness research studies

The Patient-Centered Outcomes Research Institute (PCORI) today announced funding awards totaling $208 million to support 17 new comparative clinical effectiveness research (CER) studies, including four trials of particularly large scale and scope tackling complex questions.

18 Jul 2023

Early life gut flora may play a role in juvenile idiopathic arthritis

More than ten years before being diagnosed with child rheumatism, children who developed the disease had a gut flora differing in several ways from that of children who remained healthy.

5 Jul 2023

Interdisciplinary guidelines for treatment of children with arthritis of the jaw

Interdisciplinary guidelines to optimize the treatment of childhood arthritis at global level. So far, there no uniform guidelines have existed for the treatment of arthritis of the jaw, a potentially debilitating consequence of juvenile arthritis.

20 Nov 2022