Kidney Stone News and Research

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Oral molecule prevents kidney stones and restores survival in mice

Scientists at the Buck Institute for Research on Aging have shown that an orally administered small molecule, N-propargylglycine (N-PPG), can completely prevent the formation of calcium oxalate kidney stones, protect against kidney failure, and fully restore normal survival in a mouse model of Primary Hyperoxaluria Type 2 (PH2), a rare and currently untreatable genetic disorder that causes progressive kidney failure in infants and young adults.

2 Apr 2026

Hydration programs found insufficient to reduce kidney stone recurrence

Kidney stones can cause some of the most intense pain people ever experience, affecting daily life and leading many to hospital emergency visits.

19 Mar 2026

Opioids offer limited short-term relief for acute pain

The world's largest review of opioid pain relievers prescribed for acute pain found these medicines provide only small, short-term relief for some acute conditions and are ineffective for some others.

25 Feb 2026

Study reveals hidden bacterial role in the formation of most kidney stones

In an unexpected finding, a UCLA-led team has discovered that bacteria are present inside the most common type of kidney stone, revealing a previously unrecognized component involved in their formation.

27 Jan 2026

Scorpion peppers caused him ‘crippling’ pain. Two years later, The ER bill stung him again.

Maxwell Kruzic said he was in such "crippling" stomach pain on Oct. 5, 2023, that he had to pull off the road twice as he drove himself to the emergency room at Mercy Regional Medical Center in Durango, Colorado. "It was the worst pain of my life," he said.

19 Dec 2025

New Lancet case study series highlights how social forces shape patient health

In November, The Lancet, one of the world's most esteemed medical journals, launched a new monthly series of case studies that goes beyond clinical diagnoses to illuminate the social and cultural forces that contribute to each patient's condition.

5 Dec 2025

New Lancet series blends social science with medicine to tackle global health inequities

Can doctors in California learn from a patient who was bounced from one specialist to another in Japan? Can clinicians in London take lessons from a patient seeking asylum while suffering a medical emergency at the U.S.-Mexico border? Can doctors treating refugees in Africa inform health policy around the world?

5 Dec 2025

Shift workers face higher risk of developing kidney stones

A study evaluating how various shift work patterns contribute to kidney stone risk has revealed that shift workers have a 15% higher risk of developing kidney stones, especially younger workers and those with low levels of manual labor.

2 Oct 2025

Big loopholes in hospital charity care programs mean patients still get stuck with the tab

Quinn Cochran-Zipp went to the emergency room three times with severe abdominal pain before doctors figured out she had early-stage cancer in the germ cells of her right ovary.

25 Sep 2025

New technique improve success rates in treating strokes and other clot-related diseases

When treating an ischemic stroke – where a clot is blocking the flow of oxygen to the brain – every minute counts.

4 Jun 2025

Low testosterone linked to higher kidney stone risk in men, study finds

A large cross-sectional study in South Korea found that men with low testosterone levels (below 3.33 ng/mL) were significantly more likely to have kidney stones. This association held even after adjusting for age and metabolic risk factors, suggesting testosterone may play a protective role.

6 May 2025

Can the carnivore diet trigger kidney stones? Case study raises red flags

A case study in The American Journal of Clinical Nutrition examines how one patient’s switch to a carnivore diet increased kidney stone risk by raising calcium, uric acid, and oxalate levels while reducing protective citrate.

19 Feb 2025

Poor positioning of menstrual cup linked to kidney complications

A poorly positioned menstrual cup to capture monthly blood flow may lead to more serious complications than leakage alone, warn doctors in the journal BMJ Case Reports, after treating a young woman with uterohydronephrosis-a swollen kidney caused by blocked urine flow into the bladder.

10 Feb 2025