Micrometastases News and Research

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Six-gene signature predicts colorectal cancer recurrence after liver metastases

Researchers at The University of Texas MD Anderson Cancer Center identified a six-gene signature in microscopic colorectal cancer (CRC) liver metastases that may help predict recurrence after treatment.

9 Jul 2026

New study reveals how slow-growing cells drive breast cancer relapse

A new study by the Garvan Institute of Medical Research has uncovered a hidden mechanism explaining why breast cancer can return many years after successful treatment.

11 May 2026

New optical imaging tool allows real-time breast cancer staging

Sentinel lymph node biopsy (SLNB) is critical to breast cancer staging, yet current assessment methods remain heavily dependent on pathology expertise and time-consuming tissue processing.

28 Apr 2026

Blocking nutrient scavenging weakens pancreatic tumor defenses

Cancer cells and tumors do not exist in a vacuum. Far from the isolation and self-sufficiency of the fictional Wakanda, tumors develop in and alter the nearby milieu of immune cells, connective tissue, blood vessels and a sea of proteins and carbohydrates that provide structure and other supportive functions.

24 Jul 2025

Aspirin may help prevent cancer spread by stimulating the immune system

Scientists have uncovered the mechanism behind how aspirin could reduce the metastasis of some cancers by stimulating the immune system.

5 Mar 2025

Neoadjuvant immunotherapy yields comparable outcomes in high-risk liver cancer surgery

Patients with liver cancer who received immune checkpoint inhibitors (ICIs) before surgery - including those who would not have been eligible for surgery by conventional criteria - had similar outcomes to patients who received surgery upfront, according to results from a retrospective study.

15 Aug 2024

Navigating adjuvant therapy options in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies globally and is the third leading cause of cancer-related deaths.

16 Jul 2024

Combining CYFRA 21-1 with CXCR1 and cxcr2 levels for predicting recurrence in stage III squamous cell lung carcinoma

Despite efforts, tumor recurrence is diagnosed in 35–40% of patients with stage III squamous cell lung carcinoma (SCLC) during the first year after treatment.

25 Jun 2024

Radiation therapy combined with two types of immunotherapy could be effective against cold tumors

Researchers at Weill Cornell Medicine have discovered that radiation therapy combined with two types of immunotherapy - one that boosts T cells, and another that boosts dendritic cells - can control tumors in preclinical models of triple negative breast cancer, a cancer type that's typically resistant to immunotherapy alone.

25 Sep 2023

The Clinical Importance of Circulating Tumor DNA

Cancer remains a leading killer among medical causes of death worldwide.

31 Aug 2023

Could personalized neoantigen vaccines prevent the recurrence of pancreatic cancer and increase patient survival?

Researchers conducted a phase I clinical trial of a personalized mRNA neoantigen vaccine.

12 May 2023

Drugs to activate STING could help prevent cancer metastasis

A team of scientists at the Sloan Kettering Institute have identified the STING cellular signaling pathway as a key player in keeping dormant cancer cells from progressing into aggressive tumors months, or even years, after they've escaped from a primary tumor.

29 Mar 2023

Alzheimer’s disease protein helps skin cancer cells thrive when they metastasize to the brain

Amyloid beta, a protein known to build up in the brains of people with Alzheimer's disease, also helps skin cancer cells thrive when they spread to the brain, a new study finds.

10 Mar 2022

Pathological regression of lymph nodes better predicts survival in esophageal cancer patients

A group of researchers led by Osaka University established a new pathological grading system to evaluate the therapeutic effect of neoadjuvant chemotherapy for metastatic lymph nodes removed in esophageal cancer surgery, demonstrating that the system predicts recurrence and prognosis in EC patients better than conventional systems.

27 Jul 2020

Highly focused radiation may slow disease progression in men with oligometastatic prostate cancer

Highly focused, intense doses of radiation called stereotactic ablative radiation (SABR) may slow progression of disease in a subset of men with hormone-sensitive prostate cancers that have spread to a few separate sites in the body, according to results of a phase II clinical trial of the therapy.

26 Mar 2020

Intense and targeted radiotherapy could slow progression of certain prostate cancers

Targeted and strong doses of stereotactic ablative radiation (SABR) radiotherapy could slow progression in prostate cancer.

26 Mar 2020

Multiplexed C dots track different cancer targets to improve treatment

For more than a decade, researchers have used glowing nanoparticles called Cornell dots, or C dots, to illuminate cancer cells, target tumors and even induce cell death.

6 Dec 2019

Zoledronic acid increases disease-free survival in premenopausal women with HR+ early breast cancer

Adjuvant treatment with the bone sparing drug zoledronic acid plus hormonal therapy with the aromatase inhibitor letrozole significantly increases disease-free survival compared to tamoxifen in premenopausal women with hormone receptor positive (HR+) early breast cancer, according to results reported at ESMO 2018 Congress in Munich.

22 Oct 2018

Changes in skin and lymphatic system due to age facilitate melanoma metastasis

Changes in the structure of the skin and the lymphatic system that occur with the natural aging process create permissive conditions for melanoma metastasis, according to two studies by The Wistar Institute.

3 Oct 2018

Study shows no increased risk of breast cancer recurrence after DIEP flap reconstruction

After surgery for breast cancer women who have undergone breast reconstruction using abdominal tissue do not have a higher risk of recurrence than women who have not undergone breast reconstruction. This has been shown by researchers at Karolinska Institutet in a study published in the British Journal of Surgery.

23 Apr 2018