Neurodegenerative Diseases News and Research

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Brain-protecting immune cells may actually drive Alzheimer's disease

Immune cells that normally protect the body from damage by attacking foreign or infected cells are found in the brains of patients with Alzheimer's disease and related disorders at much higher levels than in healthy brains.

3 Sep 2026

Generative AI helps scientists design entirely new RNA transporters

Researchers at Helmholtz Munich and TUM have developed Synthetic Transfer Vehicles (STVs), an entirely new class of RNA transporters.

2 Sep 2026

AI platform uncovers new molecular targets for Alzheimer's disease

Groundbreaking study published in Alzheimer's & Dementia reveals the crucial links between the NAD⁺-mitophagy axis and neurodegeneration.

1 Sep 2026

People with diabetes may have another reason to protect their cardiovascular health

Better cardiovascular health, measured using Life’s Essential 8, was associated with a lower risk of mild cognitive impairment among people with diabetes after accounting for genetic susceptibility. Associations with dementia varied by genetic risk, while higher LE8 scores were also linked to greater gray matter volume and lower white matter hyperintensity volume.

30 Aug 2026

Primate-specific DNA change reveals a new link to dementia-related neurodegeneration

Brain diseases, including dementia, have long been studied using experimental animals such as mice. However, differences between the human and animal genomes have raised concerns that some disease mechanisms may not be fully explained by conventional animal models.

29 Aug 2026

Stanford scientists develop an ultracompact gene activation tool

The ability to precisely adjust the expression of genes inside the human body - ramping up protective ones and tamping down harmful ones - holds enormous potential for treating and preventing disease.

28 Aug 2026

Parkinson’s disease imposes €22.8 billion economic burden across Europe

The annual societal cost of Parkinson's disease across Europe reached €22.8 billion in 2019, equivalent to €28.8 billion at 2025 prices, a new study published today in Movement Disorders has shown.

27 Aug 2026

Egg yolk peptides protect brain cells from oxidative stress

As the human lifespan increases, so too does the risk of developing neurological disorders such as Parkinson's disease, Alzheimer's disease, anxiety and depression.

27 Aug 2026

Brain organoids reveal how Alu-mediated gene deletion can lead to neurodegeneration

Brain diseases, including dementia, have long been studied using experimental animals such as mice.

27 Aug 2026

Internet-controlled brain implant enables remote neural stimulation and drug delivery

A researcher in Chicago remotely controls a miniaturized brain implant in Daejeon, Korea - over the internet. Korean researchers have developed a wireless device that can deliver drugs and light to precisely modulate targeted neurons from anywhere in the world.

27 Aug 2026

Tea, berries and dark chocolate featured in a diet linked to lower Parkinson’s risk

A prospective UK Biobank study of 123,655 adults found that a dietary pattern richer in flavonoid-containing foods was modestly associated with a lower incidence of hospital-recorded Parkinson’s disease. The association was strongest among those with the highest flavonoid diet scores, while exploratory proteomic and transcriptomic analyses pointed to possible neuroimmune and cell-adhesion pathways but did not establish causality or mechanism.

26 Aug 2026

FDA endorses alpha-synuclein biomarker for Parkinson’s clinical trials

Critical Path Institute® (C-Path) today announced the publication of "Regulatory endorsement for the application of alpha-synuclein seed amplification assay (αSyn-SAA) as a susceptibility and risk biomarker for clinical trials targeting synucleinopathies" in the Journal of Parkinson's Disease, marking a significant milestone for its Critical Path for Parkinson's consortium.

25 Aug 2026

Shared protein pathology redefines treatment for multiple neurodegenerative diseases

On the surface, amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and limbic-predominant age-related TDP-43 encephalopathy (LATE) might seem like unrelated diseases.

24 Aug 2026

Disrupted brain-immune signaling may help drive neurodegeneration

A Cell perspective argues that neurodegeneration can emerge from disrupted communication between neural and immune networks, with peripheral immunity, microglia, and gene-regulatory programs all shaping disease processes. The authors propose that restoring immune homeostasis and recalibrating neuroimmune circuits could create new therapeutic and diagnostic opportunities, while emphasizing that many mechanisms remain unresolved in humans.

24 Aug 2026

Re:Cognition Health launches first dedicated Alzheimer's disease-modifying treatment clinic in Ireland

Re:Cognition Health, the UK's largest independent provider of Alzheimer's disease-modifying treatments, announces the opening of its first Irish clinic in Dublin, marking a major milestone in dementia care for Ireland.

19 Aug 2026

Study sheds new light on the physiological roles of protein quality control at the ribosome

Scientists at the Center for Molecular Medicine Cologne (CMMC) and the CECAD Cluster of Excellence on Aging Research have demonstrated in a biomedical study that ribosomes, the protein factories of our cells, face an unusually tough challenge when building large, membrane‑embedded proteins.

12 Aug 2026

New imaging model can detect early brain changes in Huntington's disease

Researchers have shown that an imaging model can detect microstructural abnormalities in the brain associated with Huntington's disease, potentially offering a new method for monitoring disease progression and evaluating new treatments.

11 Aug 2026

Senescent brain immune cells secrete protein linked to cognitive decline

Brain-resident immune cells that have reached an old-age state called "senescence" secrete a protein that causes dysfunction in other brain cells, according to a study led by investigators at Weill Cornell Medicine.

11 Aug 2026

Shared cellular pathway drives neurodegeneration in rare childhood dementia and Alzheimer’s

Researchers at University of California San Diego and their colleagues have identified a key cellular pathway that drives brain degeneration in both a rare childhood disorder and the far more common Alzheimer's disease.

11 Aug 2026

Nocturnal micro-awakenings linked to genetic risk of Alzheimer's disease

What if certain signs of the disease were to manifest themselves subtly during sleep, long before the first memory problems appear? This is the line of inquiry being explored by a team of researchers at ULiège, with the support of the Stop Alzheimer's Foundation.

11 Aug 2026

Neurodegenerative Diseases News and Research

Brain-protecting immune cells may actually drive Alzheimer's disease

Generative AI helps scientists design entirely new RNA transporters

AI platform uncovers new molecular targets for Alzheimer's disease

People with diabetes may have another reason to protect their cardiovascular health

Primate-specific DNA change reveals a new link to dementia-related neurodegeneration

Stanford scientists develop an ultracompact gene activation tool

Parkinson’s disease imposes €22.8 billion economic burden across Europe

Egg yolk peptides protect brain cells from oxidative stress

Brain organoids reveal how Alu-mediated gene deletion can lead to neurodegeneration

Internet-controlled brain implant enables remote neural stimulation and drug delivery

Tea, berries and dark chocolate featured in a diet linked to lower Parkinson’s risk

FDA endorses alpha-synuclein biomarker for Parkinson’s clinical trials

Shared protein pathology redefines treatment for multiple neurodegenerative diseases

Disrupted brain-immune signaling may help drive neurodegeneration

Re:Cognition Health launches first dedicated Alzheimer's disease-modifying treatment clinic in Ireland

Study sheds new light on the physiological roles of protein quality control at the ribosome

New imaging model can detect early brain changes in Huntington's disease

Senescent brain immune cells secrete protein linked to cognitive decline

Shared cellular pathway drives neurodegeneration in rare childhood dementia and Alzheimer’s

Nocturnal micro-awakenings linked to genetic risk of Alzheimer's disease

eBook: Using iPSCs models for human disease research and drug discovery eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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