Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Blocking complement factor B halts pancreatic cancer growth

Researchers have identified a promising new target in the treatment of pancreatic cancer. A new study in The American Journal of Pathology, published by Elsevier, demonstrates that blocking complement factor B (CFB), a pivotal enzyme in the alternative complement pathway, halts cancer growth and alters the tumor microenvironment.

9 Nov 2026

Qureight's fibrosis imaging biomarker selected by Contineum Therapeutics as a secondary endpoint in Phase 2 PROPEL-IPF clinical trial

Qureight, an end-to-end imaging company providing enterprise-grade imaging and precision endpoints for clinical trials for lung and heart disease, and Contineum Therapeutics, Inc. (Contineum), a clinical-stage biopharmaceutical company pioneering differentiated small molecule therapies for inflammatory and fibrotic diseases with significant unmet need, today announced that Qureight's Fibr8™ quantitative imaging biomarker is being used as a secondary endpoint in Contineum's PROPEL-IPF Phase 2 clinical trial examining the safety and efficacy of PIPE-791, Contineum's lead drug candidate, in idiopathic pulmonary fibrosis (IPF) patients.

From Qureight 9 Nov 2026

Autistic children show reading gains through online instruction tool

Despite many obstacles presented by students being at home during COVID-19 lockdowns and restrictions, the autistic children involved in this research project still showed significant progress through online instruction.

6 Nov 2026

Women with Parkinson's have higher rates of Alzheimer's pathology

A new study is shedding light on how changes associated with different neurodegenerative diseases can overlap in the brain - and how that overlap may differ between women and men.

6 Nov 2026

Metal fumes, drinking habits and dementia: What a new study found

This study examines how workplace chemicals and lifestyle habits may influence Lewy body dementia risk, revealing potential sex differences in exposure effects.

6 Nov 2026

Study shows opposite synaptic mechanisms cause identical cognitive deficits

A research team led by Dr. SHENG Nengyin of the Kunming Institute of Zoology (KIZ) of the Chinese Academy of Sciences has reframed ZC4H2-associated rare disorder (ZARD)-a disorder marked by intellectual disability, developmental delays, muscle weakness, and other neurological or physical abnormalities-as a "disease spectrum" rather than a condition driven by a single mechanism.

5 Nov 2026

Tau spreads more rapidly in early-onset Alzheimer's disease

Patients with early-onset Alzheimer's disease, whose symptoms start before age 65, have more extensive deposits of tau, a hallmark protein of the condition, compared with patients whose symptoms start at 65-plus, a new study found.

5 Nov 2026

New nanovesicle therapy shows promise for treating alcohol-related liver disease

Alcohol-related liver disease (ALD) is characterized by hepatocellular injury, oxidative stress, inflammation, and extracellular matrix remodeling, yet effective therapies remain limited.

4 Nov 2026

Vanderbilt researchers create massive transcriptomic atlas of breast cancer

A new molecular map of breast cancer has identified novel forms of the disease and provides a foundation for selecting personalized treatments guided by a tumor's molecular characteristics rather than standard pathology alone.

3 Nov 2026

Advanced imaging tool improves detection of residual multiple myeloma disease

A targeted immunoPET scan detected active multiple myeloma that standard PET/CT scans and blood tests missed, a finding that could help doctors more accurately map disease, guide treatment decisions and confirm whether cancer remains after therapy.

3 Nov 2026

Innovative AI system could prevent testing delays in clinical laboratories

Weill Cornell Medicine researchers have designed an AI system that could help clinical laboratories identify problems before they disrupt testing and delay patient care.

3 Nov 2026

Plant-derived compound helps restore cancer cells' sensitivity to treatment

A natural plant compound may help overcome a built-in defense that allows many cancers to resist a class of drugs designed to restore normal gene activity, according to a study by researchers at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center.

2 Nov 2026

New hormone receptor strategy offers targeted treatment for lupus

Researchers at the University of California, Riverside and City of Hope have identified a new strategy for treating systemic lupus erythematosus (SLE), or lupus, an autoimmune disease in which the immune system attacks healthy tissues.

2 Nov 2026

New study evaluates quantum machine learning for lung cancer prediction

Developing reliable machine learning models for healthcare can be challenging when only small datasets are available. This challenge motivates research into whether quantum computing approaches can learn useful patterns from limited symptom and risk-factor data.

2 Nov 2026

Brief dietary changes may prime the immune system for inflammation

Scientists have long known that diet shapes the immune system. Now, a UC San Francisco team has found that even a brief dietary change can substantially change how the body responds to skin irritation, at least in mice.

29 Oct 2026

Study redefines picobirnavirus as a bacteria hunting virus

Thriving alongside trillions of bacteria in the human digestive tract is a vast population of viruses. Ever since one such denizen of the gut microbiome, known as picobirnavirus, was first spotted decades ago, researchers thought it directly infected human tissue and played a role in gastrointestinal illness.

29 Oct 2026

Baylor researchers discover how glioblastoma hijacks nearby brain cells

Researchers at Baylor College of Medicine have discovered a new strategy that glioblastoma, the most common and aggressive form of adult brain cancer, uses to fuel its own growth.

27 Oct 2026

Breakthrough targeted therapy shows strong precision in treating chronic myeloid leukemia

A more effective and better-tolerated treatment for chronic myeloid leukemia (CML) could improve quality of life for people living with the disease.

27 Oct 2026

Cerebrospinal fluid liquid biopsy detects tumor DNA in complex brain cases

A Mayo Clinic study published in the Journal of Neuro-Oncology suggests that analyzing DNA in cerebrospinal fluid could provide another source of information when MRI cannot provide a clear brain tumor diagnosis or obtaining tissue through biopsy is difficult or potentially unsafe.

27 Oct 2026

Taurine helps regulate inflammation linked to aging, Yale study finds

Sustained low-level inflammation is a hallmark of the aging process. The accumulating damage persistently activates the innate immune system-the body's first line of defense-leading to what is known as inflammaging, functional decline and chronic diseases of old age.

23 Oct 2026