Psychiatric Condition News and Research

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Semaglutide outperforms other GLP-1 drugs for weight loss in psychiatric populations

A network meta-analysis of nine randomized controlled trials found that once-weekly semaglutide showed the largest estimated weight-loss effect among GLP-1 receptor agonists tested in adults with mental illness and obesity or related metabolic risk. The authors cautioned that the findings remain preliminary because the evidence base was small, heterogeneous, and largely indirect.

9 Jul 2026

LEAP2 hormone may predict anorexia nervosa relapse risk

People with anorexia nervosa have unusually high levels of a hormone called LEAP2 in their blood when they are in the acute phase of the disorder, according to research presented today (Thursday) at the Federation of European Neuroscience Societies (FENS) Forum 2026.

8 Jul 2026

Largest bipolar disorder dataset launched to advance personalized care

BD²: Breakthrough Discoveries for thriving with Bipolar Disorder today announced the first public release of data from the BD² Integrated Network Longitudinal Cohort Study (LCS).

30 Mar 2026

New research on two million people quantifies how genetic risks overlap across diagnoses

A sweeping new peer-reviewed study published in Genomic Psychiatry has introduced a concept that could reshape how psychiatrists and geneticists think about mental illness: genetic specificity.

3 Mar 2026

Why autism is diagnosed later in females than males

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9 Feb 2026

Muscle loss may persist after weight recovery in anorexia nervosa

Anorexia nervosa is a psychiatric condition characterized by a fear of weight gain and reduced calorie consumption that can result in dangerous weight loss.

5 Jan 2026

Extra sleep after the autumn clock change linked to reduced demand for NHS health services

The week after the autumn clock change is associated with a reduction in demand for NHS services for sleep disorders, cardiovascular disease, anxiety, depression, and psychiatric conditions in England, finds a study in the Christmas issue of The BMJ.

18 Dec 2025

New review illuminates the intricate connections between gut microbiota and sleep regulation

A comprehensive review published today in Brain Medicine illuminates the intricate connections between gut microbiota and sleep regulation, establishing the microbiota-gut-brain axis as a critical pathway in understanding and potentially treating sleep disorders.

4 Nov 2025

Trauma-focused CBT could offer hope for young PTSD sufferers

A specialist form of therapy could offer hope for some of the most vulnerable young PTSD sufferers – according to a University of East Anglia study.

15 Sep 2025

Blood-brain barrier dysfunction and inflammation linked to Down syndrome Regression Disorder

A new research study led by Jonathan D. Santoro, MD, Director of the Neuroimmunology Program at Children's Hospital Los Angeles, shows evidence of dysfunction of the blood-brain barrier and inflammation in the central nervous system in individuals with Down syndrome Regression Disorder (DSRD).

14 Mar 2025

For seniors with hoarding disorder, a support group helps confront stigma and isolation

A dozen people seated around folding tables clap heartily for a beaming woman: She’s donated two 13-gallon garbage bags full of clothes, including several Christmas sweaters and a couple of pantsuits, to a Presbyterian church.

6 Mar 2025

Telehealth for ADHD treatment linked to higher substance use disorder risk

For nearly five years, people with attention deficit/hyperactivity disorder have had the option of getting their stimulant medications prescribed and renewed by doctors they see only over a computer screen, despite the risks that these stimulant drugs can pose if misused.

6 Mar 2025

Study identifies genetic associations with youth psychopathology

When trying to understand how genetic influences factor into youth behavior, researchers at Washington University in St. Louis have taken the "big trawl" approach, casting their net wide to pull in all the measured traits, behaviors and environments that make up who we are and examine associations with the genetic building blocks comprising risk for mental health problems.

17 Oct 2024

Psychiatric conditions double mortality risk in anorexia nervosa patients

A new study published in the International Journal of Eating Disorders found that mortality rates are high in patients with anorexia nervosa and nearly double in the presence of psychiatric conditions.

12 Jun 2024

Understanding public perception of polygenic embryo screening for IVF

Three out of four U.S. adults support the use of emerging technologies that estimate a future child's likelihood of developing health conditions influenced by multiple genes - such as diabetes, heart disease, and depression - before an embryo is implanted during in vitro fertilization (IVF), according to a new public opinion survey led by researchers at Harvard Medical School.

15 May 2024

Academic pressure linked to higher depression risk in teens

A study in The Lancet Child & Adolescent Health links academic achievement goals to increased risk of depression in adolescents, suggesting that the pressure to outperform peers may heighten depressive symptoms.

22 Apr 2024

Metabolic markers tied to increased risk of depression and anxiety, study finds

Comprehensive study within a large Swedish cohort links elevated glucose and triglyceride levels to an increased risk of developing depression, anxiety, and stress-related disorders, while higher HDL-C levels seem protective, suggesting a significant connection between metabolic health and psychiatric conditions.

3 Apr 2024

Antipsychotic use during pregnancy not linked to childhood neurodevelopmental disorders or learning difficulties

The use of antipsychotics during pregnancy isn't linked to childhood neurodevelopmental disorders or learning difficulties, UNSW Sydney-led study shows – giving assurance to those concerned about continuing their medications during pregnancy.

18 Mar 2024

Non-communicable diseases and external causes of death are major contributors to the risk of mortality in people with OCD

Researchers investigated the risk of cause-specific and all-cause mortality in Swedish individuals with obsessive-compulsive disorder (OCD) as compared to matched unaffected individuals or siblings.

23 Jan 2024

Is there a neurobiological association between childhood trauma, alexithymia, and long-term nicotine smoking?

A new study published in JAMA Network Open explores the risk for smoking presented by childhood trauma with subsequent failure of emotional regulation and the neural measures that reflect these risk factors.

11 Jan 2024