Simian Immunodeficiency Virus (SIV) News and Research

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Simian immunodeficiency virus (SIV) is a retrovirus that is found, in numerous strains, in primates; the specific strains infecting humans are HIV-1 and HIV-2, the viruses that cause AIDS.

Low-dose THC mitigates harmful side effects and inflammation caused by HIV treatment

Long-term, low doses of THC mitigate many harmful side effects and inflammation caused by HIV and antiretroviral therapy (ART), according to new research from Texas Biomedical Research Institute.

6 Nov 2025

New study reveals key tissues involved in HIV rebound after treatment

In findings that have implications for potential new HIV therapies, researchers from Texas Biomedical Research Institute (Texas Biomed) used genetic sequencing techniques on the nonhuman primate version of the virus to identify that lymph nodes in the abdomen are the leading source of rebound infection after the first week of stopping antiretroviral treatment.

24 Jan 2024

Improving gut health may be key to slowing HIV progression to AIDS

Restoring and improving gut health may be key to slowing HIV progression to AIDS, according to a new study by University of Pittsburgh infectious diseases scientists published today in the journal JCI Insight.

24 Jul 2023

Brain microglia serve as a stable viral reservoir for latent HIV

As a part of its life cycle, the human immunodeficiency virus-1 (HIV) inserts a copy of its DNA into human immune cells. Some of these newly infected immune cells can then transition into a dormant, latent state for a long period of time, which is referred to as HIV latency.

16 Jun 2023

PETA announces $50,000 grant to explore the reasons for HIV vaccine research failures

PETA is pleased to announce that it will bankroll a $50,000 grant to fund a first-of-its-kind study to explore the exact reasons why attempts to develop a vaccine against HIV have failed to produce a viable one for humans.

8 May 2023

Tetravalent COVID vaccine provides broad antibody responses against SARS-CoV-2 variants in animal model

In a recent study posted to the bioRxiv* preprint server, researchers in Italy and the United States evaluated the efficacy and immunogenicity of an adjuvanted tetravalent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein subunit 1 (S1) COVID-19 vaccine.

21 Mar 2023

Obscure family of viruses already endemic in African monkeys "poised for spillover" to humans

An obscure family of viruses, already endemic in wild African primates and known to cause fatal Ebola-like symptoms in some monkeys, is "poised for spillover" to humans, according to new University of Colorado Boulder research published online Sept. 30 in the journal Cell.

30 Sep 2022

Knowledge, attitudes, and practices of medical professionals towards monkeypox in Italy

Researchers assessed the knowledge, attitudes, and practices (KAP) of healthcare workers (HCWs) towards monkeypox (MPX) in Italy.

29 Jul 2022

Scientists receive $3.9 million NIH grant to eradicate HIV from the brain

Finding a cure for HIV has been extremely difficult, in part because the virus hides from antiretroviral treatments in one of the hardest places to reach: the brain.

27 Jul 2022

Potential of a SARS-CoV-2 immunoPET approach to study COVID-19 dynamics in total body in rhesus macaques

In a recent study an immunoPET technique that the authors were using to analyze SIV was adapted to evaluate the spatiotemporal dynamics of SARS-CoV-2 infection in a rhesus macaque model.

2 Mar 2022

Early antiretroviral therapy is crucial to fight against HIV and latent tuberculosis

Two weeks makes a big difference in treating the animal version of HIV and latent tuberculosis, researchers from Texas Biomedical Research Institute, Southwest National Primate Research Center and colleagues report this month in the Journal of Clinical Investigation.

18 Feb 2022

Special type of stem cell can reduce the amount of HIV virus

In a groundbreaking study, a team of UC Davis researchers has discovered a special type of stem cell that can reduce the amount of the virus causing AIDS, boosting the body's antiviral immunity and repairing and restoring the gut's lymphoid follicles damaged by the simian immunodeficiency virus (SIV), the equivalent of the human immunodeficiency virus (HIV) in non-human primates.

24 Jun 2021

Texas Biomed to investigate the effects of cannabinoids on HIV-associated neurocognitive disorder

The National Institutes of Health (NIH) awarded Professor Mahesh Mohan, D.V.M., Ph.D., and collaborators more than $3.5 million over five years to investigate the effects of cannabinoids on Human Immunodeficiency Virus (HIV) associated neurocognitive disorder (HAND).

11 Dec 2020

Scientists reverse HIV latency, take major scientific step toward curative therapies

Approximately 38 million people are infected with HIV worldwide, about 1.1 million people in the United States. Currently, people with HIV take antiretroviral therapy (ART), which can suppress HIV to undetectable levels in blood, but the virus persists throughout the body in latently infected resting CD4+ T cells.

22 Jan 2020

Simian Immunodeficiency Virus (SIV) News and Research

Low-dose THC mitigates harmful side effects and inflammation caused by HIV treatment

New study reveals key tissues involved in HIV rebound after treatment

Improving gut health may be key to slowing HIV progression to AIDS

Brain microglia serve as a stable viral reservoir for latent HIV

PETA announces $50,000 grant to explore the reasons for HIV vaccine research failures

Tetravalent COVID vaccine provides broad antibody responses against SARS-CoV-2 variants in animal model

Obscure family of viruses already endemic in African monkeys "poised for spillover" to humans

Knowledge, attitudes, and practices of medical professionals towards monkeypox in Italy

Scientists receive $3.9 million NIH grant to eradicate HIV from the brain

Potential of a SARS-CoV-2 immunoPET approach to study COVID-19 dynamics in total body in rhesus macaques

Early antiretroviral therapy is crucial to fight against HIV and latent tuberculosis

Special type of stem cell can reduce the amount of HIV virus

Texas Biomed to investigate the effects of cannabinoids on HIV-associated neurocognitive disorder

Scientists reverse HIV latency, take major scientific step toward curative therapies

Timing is key: preventing infant SHIV infection by PEP

Study: Spleen and gut lymph nodes may serve as reservoir replication sites for HIV virus

UC Davis study identifies mechanism to rapidly repair leaky gut in monkeys with SIV infections

Monkey-infecting virus shows promise as potential component of future HIV vaccine

New measurable indicator could prove instrumental in fight against HIV

Researchers suggest a theory for the evolution of HIV from SIV

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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