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Drinking coffee alters your microbiome, mood, and memory

Coffee consumption influences the microbiota-gut-brain axis, affecting cognitive performance and emotional regulation through complex biological pathways.

24 Apr 2026

Inflammatory signals from vesicles increase cancer cell aggressiveness and invasiveness

Pro-inflammatory M1 macrophages involved in immune responses accelerate the progression of melanoma through the extracellular vesicles they secrete, a recent study from the University of Eastern Finland shows. The findings were published in Cell Communication and Signaling.

3 Mar 2026

Scientists map how cinnamon’s bioactives interact with cancer signaling

This review synthesizes preclinical evidence showing that cinnamon-derived compounds can modulate inflammation, oxidative stress, apoptosis, and angiogenesis through multiple cancer-related signaling pathways. While biologically plausible, the findings are largely limited to cell and animal models, underscoring the need for pharmacokinetic, safety, and clinical validation.

15 Dec 2025

Pyruvate identified as a promising oral treatment for ulcerative colitis

Ulcerative colitis (UC) is a chronic inflammatory disease marked by intestinal pain, bleeding, and impaired gut barrier function.

29 Jul 2025

Study provides a molecular snapshot of Tanshi constitution's immunological landscape

The study aims to uncover the immunological basis of Tanshi (phlegm-dampness) constitution—a subhealth type in traditional Chinese medicine (TCM)—using single-cell RNA sequencing (scRNA-seq) of peripheral blood mononuclear cells (PBMCs).

7 Jul 2025

How immune resilience and salutogenesis promote disease resistance and longevity

Researchers examine how salutogenesis, the active production of health through immune resilience, resists disease.

28 Apr 2025

Hypothalamic ECM remodeling drives insulin resistance, contributing to obesity and diabetes

Researchers have discovered that remodeling of extracellular matrix (ECM) in the hypothalamus, specifically around AgRP neurons, drives insulin resistance and metabolic disease. Disrupting this ECM buildup improves insulin sensitivity and may be a promising treatment for obesity and diabetes.

19 Sep 2024

The role of banana lectin in mitigating inflammatory bowel disease

The therapeutic role of recombinant banana lectin (rBanLec) concerning IBD control and raising vaccination rates.

3 Jun 2024

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

Resveratrol can combat Alzheimer's via inflammatory suppression, study shows

Study demonstrates Resveratrol's ability to mitigate Alzheimer's Disease (AD) symptoms by inhibiting proinflammatory responses and promoting antioxidant enzyme expression in microglial cell lines, offering insights into its neuroprotective mechanisms.

5 Feb 2024

Study reveals intestinal helminth infection diminishes T cell response to COVID-19 mRNA vaccine

Study investigates the impact of helminth infection on COVID-19 mRNA vaccine efficacy, revealing that while antibody responses remain largely unaffected, T-cell responses are significantly impaired, particularly against Omicron variants.

17 Jan 2024

Charting the future of IBD treatment: From immune modulators to microRNA therapies

In a recent study published in the journal eGastroenterology, researchers delved into the latest therapeutic strategies for managing inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. The paper discusses emerging treatments ranging from immune-modulating drugs and biologics to novel approaches like microRNA upregulators and stem cell therapies, highlighting the need for precision medicine in IBD care.

8 Nov 2023

Could spinach extract accelerate wound healing in those with diabetes?

Cardiovascular risk in psoriasis, the association between psoriatic inflammation and atherosclerosis, and the cardiovascular-risk-reducing effects of biologics

Researchers explored the impact of biological interventions in reducing cardiovascular risk among psoriasis patients.

6 Feb 2023

TNFα News and Research

Drinking coffee alters your microbiome, mood, and memory

Inflammatory signals from vesicles increase cancer cell aggressiveness and invasiveness

Scientists map how cinnamon’s bioactives interact with cancer signaling

Pyruvate identified as a promising oral treatment for ulcerative colitis

Study provides a molecular snapshot of Tanshi constitution's immunological landscape

How immune resilience and salutogenesis promote disease resistance and longevity

Hypothalamic ECM remodeling drives insulin resistance, contributing to obesity and diabetes

The role of banana lectin in mitigating inflammatory bowel disease

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Resveratrol can combat Alzheimer's via inflammatory suppression, study shows

Study reveals intestinal helminth infection diminishes T cell response to COVID-19 mRNA vaccine

Charting the future of IBD treatment: From immune modulators to microRNA therapies

Could spinach extract accelerate wound healing in those with diabetes?

Chronic inflammation's influence on TP53 mutations in leukemia evolution explored in new study

The potential of targeting mitochondria-associated programmed cell death for age-related disease treatment

The immunomodulatory and antiviral function of vitamin D

Study indicates interleukin-6-dependant pathway dysregulation as a key druggable feature of COVID-19

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

What is the role of B cells in breast cancer pathology?

Cardiovascular risk in psoriasis, the association between psoriatic inflammation and atherosclerosis, and the cardiovascular-risk-reducing effects of biologics

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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