Typhoid News and Research

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Gut immune cells help prevent severe salmonella infections

Widely recognized as the face of food poisoning, salmonella bacteria lurk in raw meat and poultry, on pets and in unpasteurized dairy products.

7 Jul 2026

African health expert: genomic sequencing enables near real-time pathogen detection

Advanced genomic sequencing techniques, like mNGS, are essential for accurate pathogen detection, crucial for effective outbreak response and patient care.

From BGI Genomics 15 Apr 2026

New typhoid conjugate vaccine shows safety and strong immune response in Africa

PATH and EuBiologics Co., LTD are pleased to announce Phase 3 results from a clinical trial of a typhoid conjugate vaccine (TCV), EuTYPH-C Inj.® Multi-dose. EuTYPH-C Inj.®

12 Nov 2025

Experimental intranasal vaccine triggers broad immune response against multiple strains of H5N1

Researchers at the University of Maryland School of Medicine's Center for Vaccine Development and Global Health (CVD) reported encouraging results from an early phase clinical trial that found an experimental intranasal vaccine triggered a broad immune response against multiple strains of H5N1 "bird flu".

6 Nov 2025

New dual-target vaccine shows promise against typhoid and Salmonella

Researchers at the University of Maryland School of Medicine's Center for Vaccine Development and Global Health (CVD) have completed a successful Phase 1 clinical trial of a novel vaccine designed to protect against both typhoid fever and invasive non-typhoidal Salmonella--two major causes of illness and death among children in sub-Saharan Africa.

8 Oct 2025

Ancient DNA sheds light on the origins of leprosy in the Americas

Hansen's Disease, more commonly known as leprosy, is a chronic disease that can lead to physical impairment. Today it exists in over 100 countries, and while the infection is treatable, access to treatment varies widely with socioeconomic conditions.

30 Jun 2025

Mass treatment with the antibiotic azithromycin may lead to increased drug resistance

Efforts to reduce child mortality in Africa via mass treatment with the antibiotic azithromycin (AZM) may lead to increased drug resistance in bacteria that frequently cause pneumonia and meningitis, highlighting the need for careful monitoring, finds a new study led by UCL.

4 Jun 2025

Researchers uncover how antibodies protect against Strep A infections

Researchers have discovered how antibodies help to protect against contagious bacterial infections caused by Strep A, including strep throat.

7 Mar 2025

Research disproves persister bacteria as main cause of antibiotic resistance

Antibiotics are indispensable for treating bacterial infections. But why are they sometimes ineffective, even when the bacteria are not resistant? In their latest study published in the journal Nature, researchers from the University of Basel challenge the conventional view that a small subset of particularly resilient bacteria are responsible for the failure of antibiotic therapies.

5 Feb 2025

Study reveals potential drug links to Dementia risk

Findings from a large-scale review indicate certain medications may influence dementia risk, offering insights for prevention and drug repurposing strategies.

23 Jan 2025

Researchers uncover mechanism of protein GBP1 in immune defense

The protein GBP1 is a vital component of our body's natural defence against pathogens. This substance fights against bacteria and parasites by enveloping them in a protein coat, but how the substance manages to do this has remained unknown until now.

12 Oct 2024

WHO report highlights the role of vaccines in reducing antibiotic use

A new report by the World Health Organization (WHO) finds that vaccines against 24 pathogens could reduce the number of antibiotics needed by 22% or 2.5 billion defined daily doses globally every year, supporting worldwide efforts to address antimicrobial resistance (AMR).

10 Oct 2024

Antibiotic resistance threatens millions of lives worldwide

More than 39 million people around the world could die from antibiotic-resistant infections over the next 25 years, according to a study published in The Lancet.

18 Sep 2024

Algorithm could identify drug-resistant bacteria from microscopy images

Artificial intelligence (AI) could be used to identify drug resistant infections, significantly reducing the time taken for a correct diagnosis, Cambridge researchers have shown.

8 Jul 2024

Largest-ever global deployment of cholera rapid diagnostic tests for better disease control

The arrival of rapid diagnostic test (RDT) kits for cholera in Malawi today signals the start of a global programme that will see more than 1.2 million tests distributed to 14 countries at high risk for cholera over the next several months.

10 Apr 2024

COVID-19 shatters decades of global health progress, slashing life expectancy

Study in The Lancet reveals COVID-19 as the second leading cause of death in 2021, disrupting three decades of progress in global health and reducing life expectancy by 2.2 years from 2019 to 2021 despite previous gains.

7 Apr 2024

Global life expectancy rises by 6.2 years since 1990 despite COVID-19 setbacks

Global life expectancy increased by 6.2 years since 1990 according to a new study published in The Lancet.

3 Apr 2024

New study highlights the urgent need for typhoid vaccination in sub-Saharan Africa

There is a high burden of typhoid fever in sub-Saharan African countries, according to a new study published today in The Lancet Global Health.

12 Mar 2024

Global health boost as new vaccine SKYTyphoid gains WHO prequalification

SK bioscience and the International Vaccine Institute (IVI) announced today that the typhoid conjugate vaccine developed by SK bioscience with technology transfer from IVI has achieved the World Health Organization prequalification (PQ), which paves the way for public procurement of the vaccine by UN organizations and gives a boost to the global TCV supply.

23 Feb 2024

Evidence from Malawi: Typhoid conjugate vaccine provides protection for up to four years

Study shows that a single dose of typhoid conjugate vaccine provides over four years of protection against typhoid fever in Malawian children, proving effective across all age groups.

31 Jan 2024