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Study reveals how different plant saponins alleviate ischemic stroke

Ischemic stroke accounts for approximately 85% of all strokes and remains a major cause of death and long-term disability.

12 Oct 2026

Amphista Therapeutics announces first patient dosed in AMX-883 Phase 1 clinical trial for acute myeloid leukemia

Amphista Therapeutics Limited ('Amphista'), a leader in the discovery and development of non-cereblon / VHL targeted protein degradation (TPD) medicines, today announced dosing of the first patient in a Phase 1 trial for its lead candidate, AMX-883. Initiated following authorization from the U.S. Food and Drug Administration in June 2026, the BRAMLIE trial will investigate the safety, pharmacokinetics, and preliminary efficacy of AMX-883 monotherapy in participants with AML and high-risk MDS.

From Amphista Therapeutics 12 Oct 2026

A simple handgrip test offers new clues about long COVID

Weaker handgrip strength correlates with severe long COVID symptoms, highlighting its potential as a measure for muscle dysfunction and recovery challenges.

12 Oct 2026

Researchers followed glucose monitor users for three years and found a possible kidney benefit

A study of more than 25,000 analytical group assignments involving high-risk adults with type 2 diabetes found that sustained real-time continuous glucose monitoring (rtCGM) was associated with substantial improvements in blood sugar control over three years. Continued use was also linked to lower levels of a marker of kidney damage after three years, although researchers found no evidence that the technology preserved kidney filtration function.

12 Oct 2026

Diet drinks showed no clear weight-loss edge over water after two years

In a two-year randomized trial combining assisted weight management with an unassisted follow-up year, completers maintained average weight losses of 4.8 kg with diet drinks and 3.7 kg with water. Researchers found no significant difference between groups, but fewer than half of the 493 participants completed follow-up.

11 Oct 2026

What people ate at the start of a 20-year study was linked to their heart failure odds

Researchers linked higher baseline diet quality to lower odds of developing heart failure over 20 years among 2,159 Greek adults initially free of cardiovascular disease. Healthy-food consumption showed the most consistent association, but the observational study cannot establish that dietary changes prevent heart failure.

11 Oct 2026

Severe long Covid associated with distinct oral and lung microbiomes

A study of more than 700 people has shown that those with long Covid have distinct differences in the mix of bacteria that live in their mouths and lungs, according to a study published today (Monday) in the European Respiratory Journal.

11 Oct 2026

LSD microdosing linked to improved attention in women but not men

A pilot study suggests that low doses of LSD may have different effects on sustained attention in women and men. The findings, presented at the ECNP annual congress in Munich, are preliminary, but they add to growing evidence that people may not all respond to psychedelic microdosing in the same way.

11 Oct 2026

Better blood pressure control could prevent over 518,000 annual deaths worldwide

Effective management of high blood pressure could prevent more than 518,000 annual deaths from cardiovascular disease around the world, according to preliminary research presented at the American Heart Association's Hypertension Scientific Sessions 2026.

11 Oct 2026

Intensive breathwork reduces brain blood flow and alters neural communication

Intensive breathing exercises can reduce blood flow to the brain by up to 45% and alter communication between brain networks, according to a new brain-imaging study.

11 Oct 2026

A study links a blood protein to memory and brain changes in Down syndrome

Researchers studying 88 adults with Down syndrome and 43 controls estimated that serum β-synuclein increased approximately two decades before expected Alzheimer’s symptoms, preceding changes in other blood biomarkers. Higher levels correlated with poorer memory and brain changes, but the cross-sectional study could not distinguish whether the earliest increase reflected Alzheimer’s-related synaptic dysfunction, trisomy 21-related neurobiology, or both.

11 Oct 2026

A trial of 3,220 smokers puts cash rewards for quitting to the test

In a randomized trial of 3,220 medically underserved adults referred for lung cancer screening, adding financial incentives to usual care and free medication increased sustained smoking abstinence at six months. Offering free medication alone did not significantly increase quit rates, and adding a forward-looking mobile tool did not improve outcomes beyond the incentives.

11 Oct 2026

Blood proteins may offer new clues to gut health in celiac disease

Celiac disease is an autoimmune condition in which the immune system reacts adversely to gluten. Eating gluten causes inflammation in the gut, which can damage the intestine and impair its ability to absorb nutrients.

10 Oct 2026

Scientists identify the neuroblastoma cells that signal poor outcomes

Neuroblastoma is the most common solid tumor found outside of the brain in children, yet why some children respond well to treatment while others do not has remained poorly understood.

10 Oct 2026

A trick from tardigrades could help human blood withstand freezing

Tardigrades, also called water bears, are famous for their ability to survive nearly anything. They protect themselves in extreme environments using proteins that researchers have developed into an efficient and effective strategy to preserve human red blood cells.

10 Oct 2026

New project aims to test a protein-based therapy for Fragile X syndrome

A new research project at the University of California, Riverside, has received funding to investigate whether a novel protein-based therapy can correct abnormal brain activity associated with Fragile X syndrome.

9 Oct 2026

Routine blood test may offer clues to future dementia risk

A common blood test already carried out during routine health checks may contain clues about a person's long-term risk of dementia, according to research being presented at the ECNP Congress in Munich and recently published in the Journal of Alzheimer's Disease.

9 Oct 2026

Molecular regulator CA8 may offer new therapeutic target for type 2 diabetes

Maintaining healthy blood glucose levels involves striking a balance between the glucose produced by the liver during fasting, and the insulin released from pancreatic beta cells after meals.

9 Oct 2026

Global survey finds gaps in pediatric cardiac troponin testing

Cardiac troponin, a protein released into the blood when heart muscle is damaged, can be used as a quick measure of heart injury in adults, and testing for it has revolutionized adult cardiology. For children, however, doctors often lack data on normal troponin measurements.

9 Oct 2026

New signaling pathway enhances blood stem cell transplantation outcomes

Gene therapies are used to treat many different blood disorders. However, blood stem cells often fail to achieve their full potential after transplantation.

9 Oct 2026