Adenovirus News and Research

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Adenoviruses most commonly cause respiratory illness; however, depending on the infecting serotype, they may also cause various other illnesses, such as gastroenteritis, conjunctivitis, cystitis, and rash illness. Symptoms of respiratory illness caused by adenovirus infection range from the common cold syndrome to pneumonia, croup, and bronchitis. Patients with compromised immune systems are especially susceptible to severe complications of adenovirus infection. Acute respiratory disease (ARD), first recognized among military recruits during World War II, can be caused by adenovirus infections during conditions of crowding and stress.

Study demonstrates that ATV006 is orally bioavailable and has potent efficacy against SARS-CoV-2

A new study has revealed that ATV006, which is a 5′-hydroxyl-isobutyryl prodrug, possesses extraordinary oral pharmaco-kinetic (PK) profiles in rats and cynomolgus monkeys and exhibited significant antiviral activity against ancestral SARS-COV-2 strain as well as VOCs.

20 May 2022

Update: CDC continues to identify and investigate hepatitis of unknown cause impacting children

The Centers for Disease Control and Prevention (CDC) continues to work with health departments and clinicians nationwide to identify and investigate hepatitis of unknown cause impacting children.

19 May 2022

sCPD9: a SARS-CoV-2 nasal vaccine candidate that may have superior efficacy

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19 May 2022

Neutralizing antibody responses induced by COVID-19 vaccines against SARS-CoV-2 variants

In a new study, researchers evaluated the ability of vaccine-induced antibodies to recognize and neutralize various SARS-CoV-2 variants of concern in SARS-CoV-2-naive health care workers in the Netherlands.

19 May 2022

Study investigates COVID-19 vaccination in pregnancy

A new study discusses the risk of COVID-19-related complications in pregnancy and the role of vaccination in reducing this risk.

17 May 2022

SARS-CoV-2 Omicron BA.2 differs antigenically from previous variants

Researchers observed that the SARS-CoV-2 Omicron BA.2 variant is immunologically different from other variants, including Omicron BA.1.

16 May 2022

An Ad5 vectored COVID vaccine expressing an S1-N fusion protein

In a recent study posted to the bioRxiv* preprint server, researchers characterized the development of multiple adenovirus-vectored and subunit recombinant protein severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidates.

12 May 2022

Imprinted antibody responses towards SARS-CoV-2 Omicron subvariants

A new study analyzed the imprinted antibody responses towards the SARS-CoV-2 Omicron subvariants.

12 May 2022

Discovery of host co-factors necessary for SARS-CoV2 infection

A new study published in the journal EMBO Reports has reported on the shedding of two proteases, namely, ADAM10 and ADAM17, which aids in S protein-dependent molecular events.

11 May 2022

Vaccine features that could induce durable humoral immune responses against SARS-CoV-2

A new study explored key vaccine features which could help induce and preserve humoral immunity against SARS-CoV-2 infection.

11 May 2022

The potential impact of oral vaccination against COVID-19 on transmission to naïve individuals studied in a hamster infection model

A recent article published in Science Translational Medicine demonstrated that mucosally delivered adenovirus type 5 (Ad5)-based COVID-19 vaccination minimized COVID-19 transmission and severity.

9 May 2022

Acute hepatitis and adenovirus infection among pediatric patients in Alabama

A new study published by the Centers for Disease Control and Prevention (CDC) today, "Acute Hepatitis and Adenovirus Infection Among Children -; Alabama, October 2021–February 2022" provides additional clinical and epidemiologic information from an ongoing investigation involving children in Alabama with hepatitis (inflammation of the liver) of unknown cause.

5 May 2022

Needle- and adjuvant-free vaccination with non-infectious T4-COVID nanoparticles induces strong immunity in mice

Researchers developed a mucosal vaccine for COVID-19 based on bacteriophage.

3 May 2022

Chimeric Delta-Omicron RBD-dimer vaccine found to be effective against SARS-CoV-2 variants

In a new study, researchers described their self-designed chimeric receptor-binding domain-dimer vaccine approach to adapt SARS-CoV-2 variants of concern and variants of interest.

29 Apr 2022

CDC issues health alert about children identified with hepatitis and adenovirus infection

CDC today issued a nationwide health alert to notify clinicians and public health authorities about a cluster of children identified with hepatitis and adenovirus infection – and to ask all physicians to be on the lookout for symptoms and to report any suspected cases of hepatitis of unknown origin to their local and state health departments.

26 Apr 2022

Anti-SARS-CoV-2 spike antibody levels following COVID-19 BNT162b2 vaccination

Researchers assessed factors influencing the anti-severe acute respiratory syndrome coronavirus 2 spike antibodies after SARS-CoV-2 BNT162b2 vaccination.

25 Apr 2022

Incidence of venous thromboembolism following COVID-19 vaccination

Researchers investigated the association between genetic predisposition to venous thromboembolism and increased risk of thrombosis post-COVID-19 vaccination.

22 Apr 2022

Rhinovirus the main virus co-circulating with SARS-CoV-2 in children

Researchers investigate the rates at which different pathogens appear in children, both independently and alongside SARS-CoV-2.

21 Apr 2022

Studying the immune response after COVID-19 vaccination using smartwatches and fitness bands

A new study tracked subtle physiological responses to SARS-CoV-2 vaccination using smart wearable devices like smartwatches and fitness bands.

20 Apr 2022

Researchers uncover a new protective mechanism against non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease (NAFLD), commonly known as fatty liver disease, is a prevalent disease frequently seen in obese people. Having high fat content in the liver is detrimental as it is strongly associated with severe health problems like diabetes, high blood pressure, and liver cancer.

20 Apr 2022

Adenovirus News and Research

Further Reading

Study demonstrates that ATV006 is orally bioavailable and has potent efficacy against SARS-CoV-2

Update: CDC continues to identify and investigate hepatitis of unknown cause impacting children

sCPD9: a SARS-CoV-2 nasal vaccine candidate that may have superior efficacy

Neutralizing antibody responses induced by COVID-19 vaccines against SARS-CoV-2 variants

Study investigates COVID-19 vaccination in pregnancy

SARS-CoV-2 Omicron BA.2 differs antigenically from previous variants

An Ad5 vectored COVID vaccine expressing an S1-N fusion protein

Imprinted antibody responses towards SARS-CoV-2 Omicron subvariants

Discovery of host co-factors necessary for SARS-CoV2 infection

Vaccine features that could induce durable humoral immune responses against SARS-CoV-2

The potential impact of oral vaccination against COVID-19 on transmission to naïve individuals studied in a hamster infection model

Acute hepatitis and adenovirus infection among pediatric patients in Alabama

Needle- and adjuvant-free vaccination with non-infectious T4-COVID nanoparticles induces strong immunity in mice

Chimeric Delta-Omicron RBD-dimer vaccine found to be effective against SARS-CoV-2 variants

CDC issues health alert about children identified with hepatitis and adenovirus infection

Anti-SARS-CoV-2 spike antibody levels following COVID-19 BNT162b2 vaccination

Incidence of venous thromboembolism following COVID-19 vaccination

Rhinovirus the main virus co-circulating with SARS-CoV-2 in children

Studying the immune response after COVID-19 vaccination using smartwatches and fitness bands

Researchers uncover a new protective mechanism against non-alcoholic fatty liver disease

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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