Airway Inflammation News and Research

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Dupilumab considerably reduced asthma exacerbations in young children, shows VOYAGE trial

Results from the VOYAGE study of dupilumab (Dupixent) showed that the monoclonal antibody significantly reduced exacerbations in children ages 6-11 with uncontrolled moderate-to-severe asthma, compared to placebo, according to research presented at the ATS 2021 International Conference. VOYAGE (NCT02948959) is a recently completed randomized, placebo-controlled double-blind multicenter phase 3 clinical trial, that took place in a number of countries.

20 May 2021

Phase 3 trial: New biologic therapy improves outcomes in adults, adolescents with severe asthma

Results from the NAVIGATOR study of tezepelumab showed that the new biologic therapy significantly reduced exacerbations requiring hospital stays and emergency department (ED) visits for adults and adolescents with severe, uncontrolled asthma, according to research presented at the ATS 2021 International Conference.

20 May 2021

Apply for your NObreath® FeNO breath monitor today and optimise patient asthma care

NHS Organisations can apply for funding from the Pathway Transformation Fund (PTF) to obtain a NObreath® used for asthma diagnosis and management.

25 Mar 2021

Delays in TB diagnosis often exceed WHO’s recommendations, shows study

Tuberculosis remains a rare disease in the United States, but when it does occur, delays in diagnosing it often exceed recommendations by the World Health Organization, according to a new report by Harvard Medical School researchers published March 22 in The Lancet Infectious Diseases.

24 Mar 2021

Study shows asthma mediator IL-13 prevents SARS-CoV-2 infection

In a paper published on the bioRxiv preprint server, researchers reported the results on whether IL-13 expression in asthma patients reduces their susceptibility to SARS-CoV-2 infection.

1 Mar 2021

Novel immunotherapy approach to revert the main hallmarks of cat allergy

Researchers from the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) brought forward the potential of high doses of a specific adjuvant molecule, namely CpG oligonucleotide, in successfully modulating the immune system's allergic response to the main cat allergen Fel d 1, thereby inducing a tolerance-promoting reaction and reverting the main hallmarks of cat allergy.

5 Feb 2021

International consortium investigates specific cell signaling process across range of human diseases

Life in the digital age often throws a curveball when the signalling bars on our mobile phones drop or disappear altogether. Similarly, disruptions in the signalling networks of cells within the body can wreak havoc and lead to disease.

20 Jan 2021

Owlstone Medical introduces breath biopsy panel for respiratory diseases

Owlstone Medical, the leader in Breath Biopsy® for applications in disease detection, today introduced the Respiratory Diseases Research Use Only Panel.

From Owlstone Medical Ltd 19 Jan 2021

Researchers use urine test to identify and verify a patient's type of asthma

In a new study, researchers at Karolinska Institutet in Sweden have used a urine test to identify and verify a patient's type of asthma.

13 Jan 2021

Could fenofibrate be an effective antiviral against SARS-CoV-2?

The resurgence of COVID-19 pandemic, caused by the SARS-CoV-2, has led to renewed efforts to find effective antivirals, both newly developed or repurposed drugs. A study reports the efficacy of the cholesterol-reducing drug fenofibrate in reducing infection rates of SARS-CoV-2 in cultured cells.

13 Jan 2021

Hydrogen therapy may help severely ill COVID-19 patients

Researchers from the Department of Critical Care Medicine, Sichuan Provincial People's Hospital, Chengdu in China, have explored the possibility of using hydrogen therapy on severely ill COVID-19 patients. The team published their study's findings, titled "Hydrogen: A Potential New Adjuvant Therapy for COVID-19 Patients," in the latest issue of the journal Frontiers in Pharmacology.

17 Nov 2020

Researchers find a better way to block asthma triggers

Every day, ten Americans die from asthma. While quick-acting inhalers and medications can reduce inflammation during an asthma attack, people with asthma have few tools to prevent the next attack from coming.

11 Nov 2020

Animal data supports efficacy of baricitinib vs SARS-COV-2

The high burden of disease caused by the COVID-19 pandemic has led to much research on effective ways to mitigate the health, social, and economic impact of the spread of the infection. A recent study published on the preprint server bioRxiv* in September 2020 reports on the characteristics of the drug baricitinib when used as monotherapy to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Sep 2020

Asthma does not appear to increase the risk of COVID-19, shows study

Asthma does not appear to increase the risk for a person contracting COVID-19 or influence its severity, according to a team of Rutgers researchers.

6 Jul 2020

New study explores post-COVID-19 inflammatory condition in children

In recent weeks, a multisystem hyperinflammatory condition has emerged in children in association with prior exposure or infection to SARS-CoV-2.

25 Jun 2020

Active ingredient from parasite larvae could help treat asthma

The larvae of the roundworm Heligmosomoides polygyrus bakeri (Hpb) need a very special environment in order to survive: They have to invade the mucosal layer of the intestine in rodents, the only place where they can then develop into adult worms capable of reproduction.

24 Apr 2020

‘Entry Point’ enzyme for COVID-19 higher in COPD patients and smokers

News-Medical speaks to Professor Don Sin on his research into COVID-19 and its effect on smokers and people suffering from COPD.

9 Apr 2020

A special diet can help in certain cases of asthma, study suggests

Can a special diet help in certain cases of asthma? A new study at the University of Bonn at least points to this conclusion. According to the study, mice that were switched to a so-called ketogenic diet showed significantly reduced inflammation of the respiratory tract.

7 Apr 2020

Review: A plant-based diet can help prevent and manage asthma

A plant-based diet can help prevent and manage asthma, while dairy products and high-fat foods raise the risk, according to a new review published in Nutrition Reviews.

27 Mar 2020