Amyloidosis News and Research

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Amyloidosis is the term applied to a group of conditions caused by deposits of an abnormal protein called amyloid. This rare but serious condition affects between 1 and 5 people in every 100,000 each year in the UK. The condition is mainly seen among the elderly.

Foie gras can speed amyloid development

University of Tennessee Graduate School of Medicine professor and researcher Alan Solomon, M.D., director of the Human Immunology and Cancer/Alzheimer's Disease and Amyloid-Related Disorders Research Program, led a team that discovered a link between foie gras prepared from goose or duck liver and the type of amyloid found in rheumatoid arthritis or tuberculosis.

19 Jun 2007

New aspect of prion disease - agent causes heart damage

Until now, prion disease has been thought of as a chronic neurological condition.

9 Jul 2006

Restricting carbohydrates may prevent Alzheimer's disease

A recent study directed by Mount Sinai School of Medicine suggests that experimental dietary regimens might calm or even reverse symptoms of Alzheimer's Disease (AD).

14 Jun 2006

Persistent amyloidosis following suppression of Ab production in a transgenic model of Alzheimer disease

Alzheimer Disease (AD) is characterized by hallmark lesions called amyloid plaques in the brain.

20 Nov 2005

Scintigraphy scan may help clinicians properly diagnose and then treat two forms of cardiac amyloidosis

"Clinically, this finding helps differential diagnosis and reduces the risk of misdiagnosis between two conditions with very different therapeutic options," said Claudio Rapezzi, M.D. from the University of Bologna and S. Orsola-Malpighi Hospital in Bologna, Italy.

21 Sep 2005

Faulty folding of protein in the environment may cause disease

Serious diseases like Alzheimer's and type-2 diabetes have been shown to be related to unhealthy protein chains that occur when proteins fold incorrectly. In an article in the scientific journal Proceedings of the National Academy of Science, PNAS, a research team directed from Uppsala University shows that similar protein chains in our environment may hasten the process.

4 May 2005

Short segments of sugar chains useful in search for new drugs for Alzheimer's

Heparansulfate, which is needed for normal fetal development among other things, is also important for the build-up of amyloid, morbid protein deposits that appear in several serious diseases. This is shown by Uppsala scientists in an article published in the Proceedings of the National Academy of Science.

19 Apr 2005

Why different tissues in the human body vary in their susceptibility to "amyloid" diseases

Researchers at The Scripps Research Institute are reporting the results of a recent study that addresses why different tissues in the human body vary in their susceptibility to "amyloid" diseases, which include Alzheimer's disease and a cluster of ailments called the familial amyloidoses.

7 Apr 2005