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Study confirms QT-prolonging effects of grapefruit juice

Grapefruit juice is already listed as a substance to avoid when taking QT-prolonging medications because it increases the toxicity of many drugs.

9 May 2019

Regular dietary peanut consumption after immunotherapy may extend allergy treatment benefits

Regular dietary peanut consumption after completing oral immunotherapy or sublingual immunotherapy for peanut allergy may provide continued protection against accidental exposures to the allergen, according to a new study led by Edwin Kim, MD, who presented the findings at the annual American Academy of Allergy, Asthma and Immunology conference in San Francisco.

25 Feb 2019

New ingestible capsule can be controlled using Bluetooth wireless technology

Researchers at MIT, Draper, and Brigham and Women's Hospital have designed an ingestible capsule that can be controlled using Bluetooth wireless technology. The capsule, which can be customized to deliver drugs, sense environmental conditions, or both, can reside in the stomach for at least a month, transmitting information and responding to instructions from a user's smartphone.

13 Dec 2018

Study identifies new potential target for treating major common diseases

There is a large, untapped potential for developing drugs against cancer, fibrosis and cardiovascular diseases by targeting a family of receptors known as Frizzleds, researchers at Karolinska Institutet in Sweden believe. In a new study published in Science Signaling, they identify how these receptors are activated in the cell membrane and the processes that are then triggered within the cell.

4 Dec 2018

Researchers identify pathway to resolve allergic asthma

A group of Brazilian researchers succeeded in preventing allergic asthma from progressing in experimental models by increasing the amount of a protein. This increase, in turn, blocked the CD4+ T lymphocytes responsible for producing a cytokine that triggers a cascade of events resulting in the onset and progression of the disease.

6 Nov 2018

Meta-analysis reveals effective treatment options for urticarial vasculitis

What treatments are available for patients with the rare inflammatory disease known as urticarial vasculitis? How effective are these treatments? Researchers from Charité - Universitätsmedizin Berlin embarked on a systematic review and meta-analysis to address these questions.

30 Oct 2018

Takeda presents vedolizumab phase 3 VISIBLE 1 trial results for treatment of moderately to severely active ulcerative colitis

Takeda Pharmaceutical Company Limited today announced results from the phase 3 VISIBLE 1 clinical trial evaluating the efficacy and safety of an investigational subcutaneous formulation of the gut-selective biologic vedolizumab for maintenance therapy in adult patients with moderately to severely active ulcerative colitis who achieved clinical response* at week 6 following two doses of open-label vedolizumab intravenous induction therapy.

22 Oct 2018

NCCN adds COPIKTRA capsules to NCCN Guidelines for follicular lymphoma

Verastem, Inc., focused on developing and commercializing medicines to improve the survival and quality of life of cancer patients, today announced that the National Comprehensive Cancer Network added COPIKTRA (duvelisib) capsules to the Clinical Practice Guidelines in Oncology (NCCN Guidelines) for follicular lymphoma.

8 Oct 2018

FDA approves new treatment for people with hairy cell leukemia

AstraZeneca and MedImmune, its global biologics research and development arm, announced today that the US Food and Drug Administration has approved LUMOXITI (moxetumomab pasudotox-tdfk) for the treatment of adult patients with relapsed or refractory hairy cell leukemia who have received at least two prior systemic therapies, including treatment with a purine nucleoside analog.

14 Sep 2018

EC grants marketing authorization for ONPATTRO (patisiran) in Europe

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that the European Commission (EC) has granted marketing authorization for ONPATTRO (patisiran) for the treatment of hereditary transthyretin-mediated (hATTR) amyloidosis in adults with stage 1 or stage 2 polyneuropathy.

30 Aug 2018

Study reveals how immune cells in the brain influence sexual behavior

Researchers have found a surprising new explanation of how young brains are shaped for sexual behavior later in life.

14 Aug 2018

FDA approves first targeted RNA-based treatment for rare, fatal genetic disease

The U.S. Food and Drug Administration today approved Onpattro (patisiran) infusion for the treatment of peripheral nerve disease (polyneuropathy) caused by hereditary transthyretin-mediated amyloidosis (hATTR) in adult patients.

10 Aug 2018

New eye drop may be potentially effective in treating seasonal eye allergies

A recent study shows that a new eye drop may be a potentially effective treatment for seasonal eye allergies, a condition affecting millions of people worldwide.

4 May 2018

Targeting opioid receptor offers relief for chronic itching

A common side effect of opioids is intense itching -- a problem for some patients who need the drugs for pain relief and for others fighting addiction.

17 Apr 2018

Researchers study how often healthcare providers prescribe anticholinergics for older adults

Anticholinergics are a class of medications that are often prescribed for allergies, lung disease, and urinary incontinence. They also often can increase health risks for older adults.

5 Apr 2018

Getting better prepared to treat in-flight medical emergencies

"Ladies and gentlemen, is there a physician on board?" The flight attendant on a flight from Rwanda to Turkey made the announcement no one wants to hear, and Rachel Zang, MD, an Emergency Medicine resident at the Hospital of the University of Pennsylvania, jumped into action.

31 Mar 2018

A push to get older adults in better shape for surgery

Surgery can be hard on older adults, resulting in serious complications and death far more often than in younger patients. But many seniors aren't adequately prepared for the risks they might face.

25 Jan 2018

Pharmaceutical pollution can make aquatic microbial communities resistant to drugs

In urban streams, persistent pharmaceutical pollution can cause aquatic microbial communities to become resistant to drugs. So reports a new study published today in the journal Ecosphere.

9 Jan 2018

Mountain cedar allergy season set to strike this year

Allergy specialists like Dr. Shelly Harvey are again readying themselves for mountain cedar, the annual irritant that makes noses run and eyes itch – potentially transforming the merriest of holiday well-wishers into miserable Ebenezer Scrooges.

19 Dec 2017

JTFPP guidelines offer practical advice on medications to treat seasonal allergic rhinitis

In a newly updated clinical practice guideline, published in Annals of Allergy, Asthma, and Immunology, allergists offer practical advice on the best types and amounts of medications to treat seasonal allergic rhinitis. Annals is the scientific publication of the American College of Allergy, Asthma, and Immunology.

7 Nov 2017