Chagas Disease News and Research

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Chagas (pronounced SHA-gus) disease is named after the Brazilian physician Carlos Chagas, who discovered it in 1909. It is caused by the parasite Trypanosoma cruzi, which is transmitted to animals and people by insect vectors that are found only in the Americas (mainly, in rural areas of Latin America where poverty is widespread). Chagas disease (T. cruzi infection) is also referred to as American trypanosomiasis.

People can become infected in various ways. In Chagas-endemic areas, the main way is through vectorborne transmission. The insect vectors are called triatomine bugs. These blood-sucking bugs get infected by biting an infected animal or person. Once infected, the bugs pass T. cruzi parasites in their feces. The bugs are found in houses made from materials such as mud, adobe, straw, and palm thatch. During the day, the bugs hide in crevices in the walls and roofs. During the night, when the inhabitants are sleeping, the bugs emerge. Because they tend to feed on people’s faces, triatomine bugs are also known as “kissing bugs.” After they bite and ingest blood, they defecate on the person. The person can become infected if T. cruzi parasites in the bug feces enter the body through mucous membranes or breaks in the skin. The unsuspecting, sleeping person may accidentally scratch or rub the feces into the bite wound, eyes, or mouth.
Penn, UGA scientists awarded new contract to develop genome database for microbial pathogens

Penn, UGA scientists awarded new contract to develop genome database for microbial pathogens

DNDi awarded USAID grant to develop new treatments for river blindness, elephantiasis

DNDi awarded USAID grant to develop new treatments for river blindness, elephantiasis

Bayer, DNDi sign first agreement to develop new oral treatment for onchocerciasis

Bayer, DNDi sign first agreement to develop new oral treatment for onchocerciasis

Mymetics' innovative HIV vaccine candidate to enter new preclinical trial

Mymetics' innovative HIV vaccine candidate to enter new preclinical trial

Prevalence of NTDs in Latin American countries presents opportunity for US foreign policy

Prevalence of NTDs in Latin American countries presents opportunity for US foreign policy

Scientists, health officials and artists working on apps to identify disease-carrying insects

Scientists, health officials and artists working on apps to identify disease-carrying insects

Celgene Global Health, DNDi expand partnership to identify new drug candidates for NTDs

Celgene Global Health, DNDi expand partnership to identify new drug candidates for NTDs

New research identifies novel cellular factors vital for CCHFV infection

New research identifies novel cellular factors vital for CCHFV infection

GHIT Fund announces new grants to tackle malaria, chagas disease and dengue

GHIT Fund announces new grants to tackle malaria, chagas disease and dengue

Fogarty receives three grants for research focused on biodiversity conservation

Fogarty receives three grants for research focused on biodiversity conservation

Vaccine for Chagas disease expected to be available within the next three years

Vaccine for Chagas disease expected to be available within the next three years

Researchers to develop global database on situation and evolution of Chagas disease

Researchers to develop global database on situation and evolution of Chagas disease

Researchers prove that CD27 drug is true alternative against malaria

Researchers prove that CD27 drug is true alternative against malaria

Wild fleas transmit Chagas' disease in some regions of Latin America

Wild fleas transmit Chagas' disease in some regions of Latin America

Melanoma in adulthood can be reduced by consistent use of sunscreen in childhood

Melanoma in adulthood can be reduced by consistent use of sunscreen in childhood

Researchers develop new method for isolating, genome sequencing individual malaria parasite cell

Researchers develop new method for isolating, genome sequencing individual malaria parasite cell

GHIT Fund announces grants to speed up innovative drug development for neglected diseases

GHIT Fund announces grants to speed up innovative drug development for neglected diseases

Scientist receives $147,157 grant from NIH to find cure for infectious disease

Scientist receives $147,157 grant from NIH to find cure for infectious disease

A-PARADDISE consortium obtains funds to develop innovative therapies for neglected parasitic diseases

A-PARADDISE consortium obtains funds to develop innovative therapies for neglected parasitic diseases

Researchers develop a class of compounds that may help eradicate Chagas disease

Researchers develop a class of compounds that may help eradicate Chagas disease