Chromosome News and Research

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In the nucleus of each cell, the DNA molecule is packaged into thread-like structures called chromosomes. Each chromosome is made up of DNA tightly coiled many times around proteins called histones that support its structure.

Chromosomes are not visible in the cell’s nucleus—not even under a microscope—when the cell is not dividing. However, the DNA that makes up chromosomes becomes more tightly packed during cell division and is then visible under a microscope. Most of what researchers know about chromosomes was learned by observing chromosomes during cell division.

Each chromosome has a constriction point called the centromere, which divides the chromosome into two sections, or “arms.” The short arm of the chromosome is labeled the “p arm.” The long arm of the chromosome is labeled the “q arm.” The location of the centromere on each chromosome gives the chromosome its characteristic shape, and can be used to help describe the location of specific genes.
Researchers develop and validate new assay that detects gene fusions in solid tumors

Researchers develop and validate new assay that detects gene fusions in solid tumors

Counteracting premature aging

Counteracting premature aging

Duke researchers map evolution of sex chromosomes in fungus linked to human disease

Duke researchers map evolution of sex chromosomes in fungus linked to human disease

Researchers unravel genetic characteristics that increase risk of developing Tourette syndrome

Researchers unravel genetic characteristics that increase risk of developing Tourette syndrome

Study supports genetic testing as first-line diagnostic method for young children with epilepsy

Study supports genetic testing as first-line diagnostic method for young children with epilepsy

Large clinical study reveals the performance of Natera's Panorama® non-invasive prenatal test

Large clinical study reveals the performance of Natera's Panorama® non-invasive prenatal test

Gene's position on chromosome influences mutations, study shows

Gene's position on chromosome influences mutations, study shows

Princeton scientists test cell-culture system to aid study of HBV infections

Princeton scientists test cell-culture system to aid study of HBV infections

Methicillin use not to blame for MRSA, say researchers

Methicillin use not to blame for MRSA, say researchers

Genetic basis behind friendliness of dogs and humans uncovered in a new study

Genetic basis behind friendliness of dogs and humans uncovered in a new study

Scientists reveal key role of TLK2 gene in placenta development, embryo viability in mice

Scientists reveal key role of TLK2 gene in placenta development, embryo viability in mice

Researchers detect new gene mutation linked to Fanconi anemia

Researchers detect new gene mutation linked to Fanconi anemia

Experts develop first freely available data network for Huntington's disease research

Experts develop first freely available data network for Huntington's disease research

New technique to study genetic changes could enhance cancer diagnosis

New technique to study genetic changes could enhance cancer diagnosis

Study indicates new element involved in genome instability

Study indicates new element involved in genome instability

Fluorescent proteins found in jellyfish shed new light on DNA copying

Fluorescent proteins found in jellyfish shed new light on DNA copying

Existing drugs could help subgroup of patients with osteosarcoma, suggest scientists

Existing drugs could help subgroup of patients with osteosarcoma, suggest scientists

MIT biologists identify how the immune system eliminates genetically imbalanced cells

MIT biologists identify how the immune system eliminates genetically imbalanced cells

Penn/CHOP research helps to better understand cause of pediatric and treatment-related leukemias

Penn/CHOP research helps to better understand cause of pediatric and treatment-related leukemias

Impairment of specific gene increases susceptibility to opioid addiction and binge eating, study shows

Impairment of specific gene increases susceptibility to opioid addiction and binge eating, study shows