Chromosome News and Research

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In the nucleus of each cell, the DNA molecule is packaged into thread-like structures called chromosomes. Each chromosome is made up of DNA tightly coiled many times around proteins called histones that support its structure.

Chromosomes are not visible in the cell’s nucleus—not even under a microscope—when the cell is not dividing. However, the DNA that makes up chromosomes becomes more tightly packed during cell division and is then visible under a microscope. Most of what researchers know about chromosomes was learned by observing chromosomes during cell division.

Each chromosome has a constriction point called the centromere, which divides the chromosome into two sections, or “arms.” The short arm of the chromosome is labeled the “p arm.” The long arm of the chromosome is labeled the “q arm.” The location of the centromere on each chromosome gives the chromosome its characteristic shape, and can be used to help describe the location of specific genes.
MUHC's 'Dr. House' discovers new genetic disease and the gene responsible for it

MUHC's 'Dr. House' discovers new genetic disease and the gene responsible for it

Study reveals how the absence of Dna2 enzyme affects chromosome instability

Study reveals how the absence of Dna2 enzyme affects chromosome instability

New massive sequencing platform implemented for double factor preimplantation genetic testing

New massive sequencing platform implemented for double factor preimplantation genetic testing

Researchers reveal previously unknown genetic effect that can raise or reduce risk of heart disease

Researchers reveal previously unknown genetic effect that can raise or reduce risk of heart disease

Using molecular targeting approach to kill melanoma cells

Using molecular targeting approach to kill melanoma cells

A love of coffee and tea is mostly genetic

A love of coffee and tea is mostly genetic

Researchers identify molecule to fight myotubular myopathy

Researchers identify molecule to fight myotubular myopathy

Reducing cellular proliferation could help deplete HIV reservoir and lead to a functional cure

Reducing cellular proliferation could help deplete HIV reservoir and lead to a functional cure

Non-coding genetic variant plays key role in endothelial function and disease incidence

Non-coding genetic variant plays key role in endothelial function and disease incidence

New study provides deeper insight into chromosome segregation during mitosis

New study provides deeper insight into chromosome segregation during mitosis

Failed DNA repair triggers chromosomal chaos in cancer cells

Failed DNA repair triggers chromosomal chaos in cancer cells

Cardiovascular and Alzheimer's disease share common genetics in some individuals, study shows

Cardiovascular and Alzheimer's disease share common genetics in some individuals, study shows

New way of identifying potential cancer drugs could streamline development of therapies

New way of identifying potential cancer drugs could streamline development of therapies

Scientists identify more aggressive chemotherapy treatment for childhood brain cancer

Scientists identify more aggressive chemotherapy treatment for childhood brain cancer

Scientists decode the longest ever continuous DNA sequence

Scientists decode the longest ever continuous DNA sequence

Down syndrome may hold important clues to onset of Alzheimer's disease

Down syndrome may hold important clues to onset of Alzheimer's disease

Researchers sequence two selfish genes in the fungus Neurospora intermedia

Researchers sequence two selfish genes in the fungus Neurospora intermedia

Common gene variants linked to migraine risk in African-American children

Common gene variants linked to migraine risk in African-American children

Genetic link to erectile dysfunction discovered

Genetic link to erectile dysfunction discovered

Study highlights opposite effects of gene following different types of environmental events

Study highlights opposite effects of gene following different types of environmental events