Chromosome News and Research

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In the nucleus of each cell, the DNA molecule is packaged into thread-like structures called chromosomes. Each chromosome is made up of DNA tightly coiled many times around proteins called histones that support its structure.

Chromosomes are not visible in the cell’s nucleus—not even under a microscope—when the cell is not dividing. However, the DNA that makes up chromosomes becomes more tightly packed during cell division and is then visible under a microscope. Most of what researchers know about chromosomes was learned by observing chromosomes during cell division.

Each chromosome has a constriction point called the centromere, which divides the chromosome into two sections, or “arms.” The short arm of the chromosome is labeled the “p arm.” The long arm of the chromosome is labeled the “q arm.” The location of the centromere on each chromosome gives the chromosome its characteristic shape, and can be used to help describe the location of specific genes.
Fathers maybe passing on ovarian cancer genes to their daughters

Fathers maybe passing on ovarian cancer genes to their daughters

Hints to aging lurk in fruit flies’ germline stem cells

Hints to aging lurk in fruit flies’ germline stem cells

Next-generation ‘active genetics’ tool opens new horizons

Next-generation ‘active genetics’ tool opens new horizons

Mitochondrial DNA may play more important role in metastatic cancer than previously thought

Mitochondrial DNA may play more important role in metastatic cancer than previously thought

Study shows connection between genetic variants for ADHD and educational attainment

Study shows connection between genetic variants for ADHD and educational attainment

Researchers move closer to solving puzzle of 15q13.3 microdeletion syndrome

Researchers move closer to solving puzzle of 15q13.3 microdeletion syndrome

Free magnesium ions regulate chromosome shape, new tool shows

Free magnesium ions regulate chromosome shape, new tool shows

Researchers use gene therapy that lengthens telomeres to cure pulmonary fibrosis in mice

Researchers use gene therapy that lengthens telomeres to cure pulmonary fibrosis in mice

Discovery may offer new therapeutic approach for kids with Prader-Willi syndrome

Discovery may offer new therapeutic approach for kids with Prader-Willi syndrome

Small tweak to mammal's DNA can cause significant physical changes, study finds

Small tweak to mammal's DNA can cause significant physical changes, study finds

Researchers discover potential target genes to halt thyroid cancer progression

Researchers discover potential target genes to halt thyroid cancer progression

Children born with Down's syndrome have superior genome that compensates for disability

Children born with Down's syndrome have superior genome that compensates for disability

Modular gene enhancers may be suitable target in treatment of blood cancer

Modular gene enhancers may be suitable target in treatment of blood cancer

Three-dimensional organization of genome plays key role in gene expression, cell fate

Three-dimensional organization of genome plays key role in gene expression, cell fate

WPI professor receives Smith Family Foundation grant to explore biology of cancer cells

WPI professor receives Smith Family Foundation grant to explore biology of cancer cells

MGH study points toward potential strategy for treating X-linked disorders

MGH study points toward potential strategy for treating X-linked disorders

Study illustrates the role of alcohol in causing damage to DNA and increased cancer risk

Study illustrates the role of alcohol in causing damage to DNA and increased cancer risk

Scientists show how alcohol exposure leads to permanent genetic damage

Scientists show how alcohol exposure leads to permanent genetic damage

Study uncovers genomic targets in refractory neuroblastoma

Study uncovers genomic targets in refractory neuroblastoma

Novartis announces FDA approval of its first and only CML therapy with TFR data in product label

Novartis announces FDA approval of its first and only CML therapy with TFR data in product label