Chromosome News and Research

Latest Chromosome News and Research

Embryonic reproductive cells reveal striking genomic architecture before development

Researchers at the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have shown for the first time that, before they can start developing into egg and sperm cells, the embryonic precursors of these cells uniquely reshape the 3D organization of their genetic material.

20 Feb 2026

New approach better predicts chemotherapy response in patients with triple-negative breast cancer

Researchers at The University of Texas MD Anderson Cancer Center have developed a new computational approach designed to better account for changes in gene expression within tumors relative to their unique microenvironments.

17 Feb 2026

Study examines the relationship between leukocyte telomere length and age-related cataract

Cataracts remain the leading cause of blindness worldwide among adults over 50, despite major advances in surgical treatment.

12 Feb 2026

FDA-approved anti-seizure drug could help fight Alzheimer's disease

While physicians and scientists have long known Alzheimer's disease involves the buildup of toxic protein fragments in the brain, they have struggled to understand how these harmful fragments are produced.

12 Feb 2026

Research reveals a link between defective DNA repair and immune-driven inflammatory disease

Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature aging and embryonic lethality in mice.

31 Jan 2026

Data-driven modeling uncovers dynamic genome folding in three dimensions

Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren't used as often.

29 Jan 2026

Scientists discover spindle's self-repair mechanism for accurate cell division

Every second, millions of cells in your body divide in two. In the space of an hour, they duplicate their DNA and grow a web of protein fibers around it called a spindle.

27 Jan 2026

Unraveling liver injury mechanisms in familial hypobetalipoproteinemia

Familial Hypobetalipoproteinemia (FHBL), caused by variants in the apolipoprotein B (APOB) gene, is a rare autosomal co-dominant monogenic disorder characterized by lifelong low plasma levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C), and APOB.

24 Jan 2026

Moffitt researchers develop a new way to predict how cancer cells evolve

Researchers at Moffitt Cancer Center have developed a new way to predict how cancer cells evolve by gaining and losing whole chromosomes, changes that help tumors grow, adapt and resist treatment.

22 Jan 2026

Age-related sperm changes at imprint regions linked to autism risk

A new research paper was published in Volume 17, Issue 12 of Aging-US on December 29, 2025, titled "Age-specific DNA methylation alterations in sperm at imprint control regions may contribute to the risk of autism spectrum disorder in offspring."

16 Jan 2026

Dual pathways found for centromere specification, ensuring accurate chromosome segregation

Despite the immense amount of genetic material present in each cell, around three billion base pairs in humans, this material needs to be accurately divided in two and allocated in equal quantities.

8 Jan 2026

New DNA tests reveal hidden biological traces on Renaissance art

DNA analysis of cultural artifacts shows diverse biological profiles, but contamination and mixed signals complicate historical lineage interpretation.

8 Jan 2026

Study uncovers how aggressive breast cancer cells escape immune defenses

With a new study in the journal Science Bulletin, researchers at Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University have discovered a new way that aggressive breast cancer cells escape the immune defenses.

1 Jan 2026

New insights into how a molecular gatekeeper controls early protein modification

For years, ETH researchers have been investigating a molecular complex that plays a key role in protein synthesis. They have now discovered that this complex also contributes a crucial function in ensuring that our DNA is properly processed and “packaged”.

19 Dec 2025

Researchers discover the enzyme responsible for chromothripsis in cancer

University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which a single chromosome is shattered into pieces and rearranged in a scrambled order, allowing cancer cells to rapidly evolve and become resistant to treatment.

11 Dec 2025

Shared genetic roots of 14 psychiatric disorders revealed

Researchers from the Psychiatric Genomics Consortium (PGC) report that most genetic influences on mental illness are shared across diagnostic categories, revealing a more interconnected biological landscape than traditional classifications suggest.

11 Dec 2025

Australian researchers pinpoint specific genetic changes linked to severe AMD

Australian researchers have for the first time pinpointed specific genetic changes that increase the risk of severe, sight-threatening forms of age-related macular degeneration (AMD).

9 Dec 2025

Study reveals new genetic insights into reticular pseudodrusen in people with AMD

A study funded in part by the National Institutes of Health (NIH) has revealed important insights into the genetics of deposits in the eye, known as reticular pseudodrusen (RPD), that are linked to greater risk of vision loss among people with age-related macular degeneration (AMD).

8 Dec 2025

A slow-growing, bone-covered, noncancerous mass named as ossifying spindled and epithelioid tumor

It's not often that a pathologist gets to make a diagnosis that works for the patient by preventing treatment from occurring.

8 Dec 2025

Chemotherapy-free combination treatment outperforms traditional regimens in patients with Ph+ ALL

A chemotherapy-free combination treatment outperformed a combination of targeted therapy and chemotherapy among patients with Ph+ acute lymphoblastic leukemia (ALL) in a new study.

7 Dec 2025

Chromosome News and Research

Latest Chromosome News and Research

Embryonic reproductive cells reveal striking genomic architecture before development

New approach better predicts chemotherapy response in patients with triple-negative breast cancer

Study examines the relationship between leukocyte telomere length and age-related cataract

FDA-approved anti-seizure drug could help fight Alzheimer's disease

Research reveals a link between defective DNA repair and immune-driven inflammatory disease

Data-driven modeling uncovers dynamic genome folding in three dimensions

Scientists discover spindle's self-repair mechanism for accurate cell division

Unraveling liver injury mechanisms in familial hypobetalipoproteinemia

Moffitt researchers develop a new way to predict how cancer cells evolve

Age-related sperm changes at imprint regions linked to autism risk

Dual pathways found for centromere specification, ensuring accurate chromosome segregation

New DNA tests reveal hidden biological traces on Renaissance art

Study uncovers how aggressive breast cancer cells escape immune defenses

New insights into how a molecular gatekeeper controls early protein modification

Researchers discover the enzyme responsible for chromothripsis in cancer

Shared genetic roots of 14 psychiatric disorders revealed

Australian researchers pinpoint specific genetic changes linked to severe AMD

Study reveals new genetic insights into reticular pseudodrusen in people with AMD

A slow-growing, bone-covered, noncancerous mass named as ossifying spindled and epithelioid tumor

Chemotherapy-free combination treatment outperforms traditional regimens in patients with Ph+ ALL

Dr. Anthony Grice

Building quality into drug development for safer, faster medicines

Advancing Human Muscle Models for Drug Development and Preclinical Testing

Chromosome News and Research

Latest Chromosome News and Research

Dr. Anthony Grice

Building quality into drug development for safer, faster medicines

Advancing Human Muscle Models for Drug Development and Preclinical Testing

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