Chromosome News and Research

Latest Chromosome News and Research

Technique for genetically modifying blood stem cells brings cure for blood diseases closer

The condition of mice with a genetic blood disease called beta-thalassemia improved significantly following treatment of their blood forming cells with a gene that enabled them to produce the type of hemoglobin normally found only in the fetus.

12 Oct 2004

Genetic discovery may hold clues to the development of many cases of the most common cancers

In a study published in Nature Genetics today, a team of scientists at The Institute of Cancer Research have discovered a gene that may hold clues to the development of many cases of the most common cancers including lung, breast, prostate and colon cancers.

12 Oct 2004

Combination of computer science and biology could aid cancer research

The technique helps to show how cells modify their own genetic makeup and may allow cancer treatments to be tailored more precisely to a patient's disease.

11 Oct 2004

New targets for combating infections in medical implants

Navarre researcher, Jaione Valle Turrillas, has identified two genes that could help as targets for pharmaceutical drugs that fight the Staphylococcus aureus bacteria - one of the bacteria which causes most infections in medical implants.

8 Oct 2004

Fourth gene found for distal muscular dystrophy

MDA grantees Peter Hedera, a neurologist at Vanderbilt University in Nashville, Tenn., and Nigel Laing, a molecular biologist at the University of Western Australia, were part of a team that identified a fourth gene that, when flawed, leads to distal muscular dystrophy (DD).

4 Oct 2004

3 year study to validate bladder cancer test

A three-year study to validate a test to detect the recurrence of bladder cancer has been initiated by the National Cancer Institute (NCI), at 12 centers across the United States and Canada.

4 Oct 2004

Researchers reveal potential new role for Glivec/Imatinib

Imatinib – or Glivec as it also known – looks as if it may become an effective treatment for yet another type of cancer.

28 Sep 2004

Arsenic trioxide - invented as a treatment for a rare type of leukaemia

Arsenic trioxide – a highly poisonous substance best known as an effective weed killer or pesticide and notorious for being a favourite ‘weapon’ of choice in murder mystery novels, is being re-invented as a treatment for a rare type of leukaemia.

28 Sep 2004

Replication timing assays may allow much earlier cancer detection

Scientists have discovered a DNA sequence that is involved in controlling the timing of DNA replication. Because alterations in DNA replication timing are associated with cancer, this discovery may lead to improved methods for cancer detection.

26 Sep 2004

Researcher looks for clues to degenerative, deadly disease called Ataxia-telangiectasia

Few have heard of the degenerative, deadly disease called Ataxia-telangiectasia (A-T) but a University of Alberta researcher is hoping to provide clues to this mysterious disorder.

23 Sep 2004

New link in the growth of Ewing’s sarcoma

To develop new therapeutic approaches to cancer, it is essential to understand the long and extremely complex process that underlies it, in other words the various stages of cancer development from the initial mutation to the tumor.

23 Sep 2004

Edible vaccine for HIV AIDS

Scientists from Novosibirsk are engaged in the development of an unusual vaccine which, apart from being less expensive to produce, safe and painless to administer, is also edible.

22 Sep 2004

Experimental drug PKC412 may be the key to treating myeloproliferative disease

Scientists at Dana-Farber Cancer Institute and Brigham and Women's Hospital have prolonged the lives of mice with a rare blood disorder by using an experimental drug that blocks signals promoting runaway growth of blood cells.

21 Sep 2004

Novel strategy for stimulating the production of utrophin

Researchers at the University of Pennsylvania School of Medicine report a novel strategy for stimulating the production of utrophin – an important muscle protein in young mice – for muscular dystrophy therapy.

21 Sep 2004

Research may provide a better understanding of the mental retardation observed in Cri-du-Chat Syndrome

By specifically deleting the adhesion protein d-catenin, which is found exclusively in the brain, researchers at UCLA have found evidence that loss of d-catenin produces severe cognitive and synaptic dysfunction.

20 Sep 2004

New insights into ancient mating and migration patterns in humans

Men have been tomcatting around since time immemorial, and some traveled far from home to do it, new research suggests.

20 Sep 2004

Newly completed Chromosome 5 sequence will be a powerful tool for scientists trying to understand human disease

Four years after publicly revealing the official draft human genetic sequence, researchers have reached the halfway point in dotting the i's and crossing the t's of the genetic sentences describing how to build a human.

16 Sep 2004

New genetic test can predict cleft lip or palate

Researchers have developed a new genetic test that can help predict whether parents who have one child with the "isolated" form of cleft lip or palate are likely to have a second child with the same birth defect. Isolated clefts account for 70 percent of all cleft lip and palate cases.

10 Sep 2004

Suprising new information on the HOX genes

Researchers at the University of Bergen are now able to present new information on the HOX genes – the “software” to design animals. The findings are published in today’s issue of Nature.

10 Sep 2004

Childhood leukaemia significantly lower in Asia than in Western countries

The incidence of childhood leukaemia in Britain increased dramatically during the twentieth century. The increase has mainly affected the under-five age group, in whom the risk increased by more than 50 per cent during the second half of the century alone.

9 Sep 2004