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First map of DNA modification in the hippocampus and prefrontal cortex created

A UCLA-led study has provided an unprecedented look at how gene regulation evolves during human brain development, showing how the 3D structure of chromatin -; DNA and proteins -; plays a critical role.

9 Oct 2024

New cell therapy offers effective treatment for patients with T-cell acute lymphoblastic leukemia

A new cell therapy, targeting CD7 on leukaemia cells, gives a potentially effective treatment for patients with T-cell acute lymphoblastic leukaemia (T-ALL) who have exhausted all standard treatment options.

7 Oct 2024

Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

Researchers used stem-cell derived organoids from Crohn's disease patients to identify two molecular subtypes, paving the way for personalized treatments targeting specific disease characteristics.

2 Oct 2024

Long-lived plasma cells fail to establish after COVID mRNA vaccination, limiting long-term antibody response

Researchers found that SARS-CoV-2-specific plasma cells were largely excluded from the long-lived plasma cell compartment in the bone marrow after mRNA vaccination, explaining the short-lived antibody response.

2 Oct 2024

Beckman Coulter Life Sciences Names Joe Fox President

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From Beckman Coulter Life Sciences - Flow Cytometry 1 Oct 2024

Iron retention in skin linked to psoriasis: Could hepcidin be the missing piece in treatment?

This study reveals hepcidin's significant role in psoriasis, linking iron retention to inflammation and keratinocyte growth, suggesting new therapeutic targets.

1 Oct 2024

Discovery of antibodies that boost complement activation against K. pneumoniae

Researchers investigate antibody-dependent complement activation during Klebsiella pneumoniae infection.

30 Sep 2024

Why children with Down’s syndrome are predisposed to developing leukaemia

The study uncovers mechanisms linking Down syndrome to leukemia, emphasizing the role of oxidative stress and genetic alterations in fetal blood development.

26 Sep 2024

Combining treatments to boost tumor response in lung cancer

Researchers at the Francis Crick Institute, in collaboration with Revolution Medicines, have tested a combination of treatments in mice with lung cancer and shown that these allow immunotherapies to target non-responsive tumors.

25 Sep 2024

Optimizing research with automation: Solutions and best practices

In this interview, NewsMedical speaks with Cerba's Coen Staplers about the benefits of lab automation, including the integration of AI technologies.

From Cerba Research 25 Sep 2024

Dietary antigens reduce small intestine cancer by boosting immune T-cells

Study shows that dietary antigens can suppress small intestine carcinogenesis by activating T-cells through Peyer's patches. Adding bovine serum albumin (BSA) or ovalbumin (OVA) to antigen-free diets restored immune function and reduced tumor growth in mice.

22 Sep 2024

The Key Role of iPSC-Derived Microglia in Research and Drug Discovery

Dr. Tilman explains the functions of iPSC-derived microglia and their relevance to conditions like Alzheimer’s.

From Axol Bioscience Ltd 17 Sep 2024

Promising new approach to combat HIV

Researchers at Université de Montréal's affiliated hospital research center, the CRCHUM, say the discovery could help lessen and even eliminate viral loads in people undergoing antiretroviral therapy.

11 Sep 2024

Researchers uncover mechanism fueling prostate cancer

Researchers at the University of Michigan Health Rogel Cancer Center have uncovered a key reason why a typically normal protein goes awry and fuels cancer.

9 Sep 2024

Study reveals how sex hormones regulate immune system functions

Findings indicate that testosterone therapy in trans men alters immune system responses, suggesting implications for disease susceptibility and treatment.

6 Sep 2024

Study links monoclonal B-cell lymphocytosis to elevated melanoma risk

About 8 to 10 million Americans over age 40 have an overabundance of cloned white blood cells, or lymphocytes, that hamper their immune systems.

5 Sep 2024

The role of HPV in male fertility: New data on sperm quality and oxidative stress

Findings indicate HR-HPV infections affect sperm health, increasing oxidative stress and altering cytokine levels, emphasizing HPV's impact on male fertility.

27 Aug 2024

Engineered human cardiac tissue reveals how lupus autoantibodies damage the heart

Study demonstrates that autoantibodies in systemic lupus erythematosus (SLE) patients contribute to myocardial injury by binding to and impairing stressed cardiac cells, offering insights into potential therapeutic targets.

25 Aug 2024

New $5.8 million grant aims to transform the global landscape of TB research

A $5.8 million grant led by Adrie Steyn, Ph.D., of the University of Alabama at Birmingham and the Africa Health Research Institute, or AHRI, in Durban, South Africa, will provide user-requested infected human lung tissue and analytical services to tuberculosis researchers worldwide.

23 Aug 2024

Cytek® Biosciences automates panel design with new intelligent algorithm

With the SpectroPanel tool, Cytek Cloud transforms flow cytometry panel design, enabling rapid optimization and enhancing research capabilities for scientists.

From Cytek Biosciences 23 Aug 2024